ES2485540A1 - Compounds useful in the treatment of methylmalonic aciduria (Machine-translation by Google Translate, not legally binding) - Google Patents

Compounds useful in the treatment of methylmalonic aciduria (Machine-translation by Google Translate, not legally binding) Download PDF

Info

Publication number
ES2485540A1
ES2485540A1 ES201330171A ES201330171A ES2485540A1 ES 2485540 A1 ES2485540 A1 ES 2485540A1 ES 201330171 A ES201330171 A ES 201330171A ES 201330171 A ES201330171 A ES 201330171A ES 2485540 A1 ES2485540 A1 ES 2485540A1
Authority
ES
Spain
Prior art keywords
treatment
translation
machine
legally binding
google translate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES201330171A
Other languages
Spanish (es)
Other versions
ES2485540B1 (en
Inventor
Belén PÉREZ GONZÁLEZ
Lourdes RUIZ DESVIAT
Ana JORGE FINNIGAN
Magdalena UGARTE PÉREZ
Aurora Martínez Ruiz
Jarl UNDERHAUG
Ruma BARNEJEE
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Universidad Autonoma de Madrid
Original Assignee
Universidad Autonoma de Madrid
University of Bergen
University of Michigan
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Universidad Autonoma de Madrid, University of Bergen, University of Michigan filed Critical Universidad Autonoma de Madrid
Priority to ES201330171A priority Critical patent/ES2485540B1/en
Publication of ES2485540A1 publication Critical patent/ES2485540A1/en
Application granted granted Critical
Publication of ES2485540B1 publication Critical patent/ES2485540B1/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/17—Amides, e.g. hydroxamic acids having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine
    • A61K31/175—Amides, e.g. hydroxamic acids having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine having the group, >N—C(O)—N=N— or, e.g. carbonohydrazides, carbazones, semicarbazides, semicarbazones; Thioanalogues thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Useful compounds in the treatment of methylmalonic aciduria. The present invention relates to the use of a chemical or pharmacological chaperone containing at least one aryl group for the preparation of a medicament for the treatment and/or prevention of methylmalonic aciduria, as well as to a pharmaceutical composition particularly useful in said treatment. . (Machine-translation by Google Translate, not legally binding)

Description

imagen1image 1

imagen2image2

imagen3image3

imagen4image4

imagen5image5

imagen6image6

imagen7image7

imagen8image8

imagen9image9

imagen10image10

imagen11image11

imagen12image12

imagen13image13

imagen14image14

imagen15image15

imagen16image16

imagen17image17

– -

imagen18image18

imagen19image19

Claims (1)

imagen1image 1 imagen2image2
ES201330171A 2013-02-11 2013-02-11 Compounds useful in the treatment of methylmalonic acidity Active ES2485540B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
ES201330171A ES2485540B1 (en) 2013-02-11 2013-02-11 Compounds useful in the treatment of methylmalonic acidity

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES201330171A ES2485540B1 (en) 2013-02-11 2013-02-11 Compounds useful in the treatment of methylmalonic acidity

Publications (2)

Publication Number Publication Date
ES2485540A1 true ES2485540A1 (en) 2014-08-13
ES2485540B1 ES2485540B1 (en) 2015-05-22

Family

ID=51293348

Family Applications (1)

Application Number Title Priority Date Filing Date
ES201330171A Active ES2485540B1 (en) 2013-02-11 2013-02-11 Compounds useful in the treatment of methylmalonic acidity

Country Status (1)

Country Link
ES (1) ES2485540B1 (en)

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
ABU-SAFIEH KAYED A et al. 4-(4-Chloro-phen-yl)-1-(2-hydr-oxy-2,2-di-phenyl-acet-yl)thio-semicarbazide..Acta crystallographica. Section E, Structure reports online England 2008 00/00/2008 VOL: 64 No: Pt 12 Pags: o2305 ISSN 1600-5368 (Electronic) Doi: doi:10.1107/S1600536808035964 pubmed:21581282. página 02305 *
JORGE-FINNIGAN A et al. POTENTIAL PHARMACOLOGYCAL CHAPERONE THERAPY FOR ISOLATED METHYLMALONIC ACIDURIA cbIB TYPE.Journal of Inherited Metabolic Disease AUG 2010 00/08/2010 VOL: 33 No: Suppl. 1 Pags: S40 ISSN 0141-8955, resumen *
KUCUKGUZEL G et al. Synthesis and biological activity of 4-thiazolidinones, thiosemicarbazides derived from diflunisal hydrazide.EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 20060301 EDITIONS SCIENTIFIQUE ELSEVIER, PARIS, FR 01/03/2006 VOL: 41 No: 3 Pags: 353 - 359 ISSN 0223-5234 Doi: doi:10.1016/j.ejmech.2005.11.005, página 355, compuesto 4 a- g. *

Also Published As

Publication number Publication date
ES2485540B1 (en) 2015-05-22

Similar Documents

Publication Publication Date Title
CY1120703T1 (en) HETEROCYCLE COMPOUNDS AND THEIR USES
CY1119058T1 (en) IMIDAZOPYRROLIDINONE COMPOUNDS
EA201690598A1 (en) AMINOGETEROARIL BENZAMIDES AS KINASE INHIBITORS
BR112016028288A2 (en) compound, pharmaceutical composition, methods for treating an individual with a disease or condition and for inhibiting kinase, and use of a compound.
CL2015002767A1 (en) Therapeutic compounds and compositions
CL2015000295A1 (en) Compounds derived from alkylpyrimidine; pharmaceutical composition that includes them; Use for the treatment of viral infections and other diseases.
BR112016011755A2 (en) derived from urea or pharmacologically acceptable salt thereof
EA201690127A1 (en) COMPOSITION BASED ON SYK INHIBITORS
EA201600204A1 (en) HINAZOLINE DERIVATIVES, PHARMACEUTICAL COMPOSITION ON THEIR BASIS AND THEIR APPLICATION FOR THE PREVENTION OR TREATMENT OF THE TUMOR
EA201690372A1 (en) AZAPIRIDON COMPOUNDS AND THEIR APPLICATION
EA201001205A1 (en) COMPOUNDS CONTAINING CYCLOBUTOXY GROUP
CY1122313T1 (en) ORBEPITANTE FOR THE TREATMENT OF CHRONIC IGNITION
EA201591805A1 (en) OXABICICLO [2.2.2] ACIDS - MODULATORS GPR120
BR112015016585A2 (en) TRIAZINE-BASED RADIOPHARMACEUTICAL COMPOUNDS, METAL COMPLEXES AND PHARMACEUTICAL COMPOSITION INCLUDING SAID COMPLEXES
CL2015000615A1 (en) Compounds derived from 4-amino-quinolines, rip2 kinase inhibitors; pharmaceutical composition that includes them; use for the treatment of diseases such as crohn&#39;s disease, ulcerative colitis or blau syndrome.
BR112014025041B8 (en) PHARMACEUTICAL COMPOSITION
EA201600124A1 (en) NEW INDOLESINE COMPOUNDS, METHOD OF THEIR PRODUCTION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
EA201890532A1 (en) NEW ANNELED BENZAMIDES
EA201592268A1 (en) DIHYDROPYRIDINONE INHIBITORS MGAT2
BR112017005242A2 (en) compound, pharmaceutical composition, and compound for use.
PH12018500378A1 (en) Novel annelated phenoxyacetamides
AR094707A1 (en) COMPOUND OF QUINAZOLIN-4-AMINA, PHARMACEUTICAL COMPOSITION THAT INCLUDES IT AND ITS USE FOR THE TREATMENT OF A DISEASE MEDIATED BY THE RIP2 KINASE
EA201591698A1 (en) MACRO CYCLIC INHIBITORS OF KINASE LRRK2
BR112017012406A2 (en) fixed ratio formulation of insulin glargine / lixisenatide
ECSP14014778A (en) COMPOSITIONS DERIVED FROM CHITOSANE

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 2485540

Country of ref document: ES

Kind code of ref document: B1

Effective date: 20150522

PC2A Transfer of patent

Owner name: UNIVERSIDAD AUTONOMA DE MADRID

Effective date: 20150825