ES2478690B1 - PHENOLIC EXTRACTS OF UNCARIA TOMENTOSA L. (CAT CLAW) CONTAINING PROCIANIDINS, PROPELARGONIDINS AND FLAVANOLIGNANS, PROCEDURE OF OBTAINING AND ITS APPLICATIONS - Google Patents

PHENOLIC EXTRACTS OF UNCARIA TOMENTOSA L. (CAT CLAW) CONTAINING PROCIANIDINS, PROPELARGONIDINS AND FLAVANOLIGNANS, PROCEDURE OF OBTAINING AND ITS APPLICATIONS Download PDF

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Publication number
ES2478690B1
ES2478690B1 ES201231962A ES201231962A ES2478690B1 ES 2478690 B1 ES2478690 B1 ES 2478690B1 ES 201231962 A ES201231962 A ES 201231962A ES 201231962 A ES201231962 A ES 201231962A ES 2478690 B1 ES2478690 B1 ES 2478690B1
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ES
Spain
Prior art keywords
flavanolignans
obtaining
extracts
procedure
uncaria tomentosa
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES201231962A
Other languages
Spanish (es)
Other versions
ES2478690A1 (en
Inventor
María Monagas Juan
Fernando SÁNCHEZ PATÁN
Jesús Eduardo QUINTANILLA LÓPEZ
Rosa Lebrón Aguilar
Begoña BARTOLOMÉ SUALDEA
Mirtha NAVARRO HOYOS
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Universidad de Costa Rica
Consejo Superior de Investigaciones Cientificas CSIC
Original Assignee
Universidad de Costa Rica
Consejo Superior de Investigaciones Cientificas CSIC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Universidad de Costa Rica, Consejo Superior de Investigaciones Cientificas CSIC filed Critical Universidad de Costa Rica
Priority to ES201231962A priority Critical patent/ES2478690B1/en
Priority to PCT/ES2013/070876 priority patent/WO2014096488A1/en
Publication of ES2478690A1 publication Critical patent/ES2478690A1/en
Application granted granted Critical
Publication of ES2478690B1 publication Critical patent/ES2478690B1/en
Priority to CR20150334A priority patent/CR20150334A/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/74Rubiaceae (Madder family)
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105Plant extracts, their artificial duplicates or their derivatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9789Magnoliopsida [dicotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • A61P39/06Free radical scavengers or antioxidants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/10General cosmetic use

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Mycology (AREA)
  • Botany (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Birds (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Medical Informatics (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Dermatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nutrition Science (AREA)
  • Polymers & Plastics (AREA)
  • Food Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Cosmetics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Extractos fenólicos de Uncaria tomentosa L. (uña de gato) que contienen procianidinas, propelargonidinas y flavanolignanos, procedimiento de obtención y sus aplicaciones.#Esta invención se refiere a extractos fenólicos conteniendo procianidinas, propelargonidinas y flavanolignanos, con propiedades/actividades potencialmente beneficiosas para la salud humana, y obtenidos a partir de las partes aéreas y de la madera interna de la planta Uncaria tomentosa L, así como al procedimiento de obtención de dichos extractos. Estos extractos son útiles para elaborar aditivos alimentarios, composiciones cosméticas y composiciones farmacéuticas con actividad antioxidante, antimicrobian, citotóxica y antiproliferativa.Phenolic extracts of Uncaria tomentosa L. (cat's claw) containing procyanidins, propelargonidines and flavanolignans, method of obtaining and their applications. # This invention relates to phenolic extracts containing procyanidins, propelargonidines and flavanolignans, with properties / activities potentially beneficial for human health, and obtained from the aerial parts and internal wood of the Uncaria tomentosa L plant, as well as the procedure for obtaining said extracts. These extracts are useful for making food additives, cosmetic compositions and pharmaceutical compositions with antioxidant, antimicrobian, cytotoxic and antiproliferative activity.

Description



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Claims (1)



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ES201231962A 2012-12-18 2012-12-18 PHENOLIC EXTRACTS OF UNCARIA TOMENTOSA L. (CAT CLAW) CONTAINING PROCIANIDINS, PROPELARGONIDINS AND FLAVANOLIGNANS, PROCEDURE OF OBTAINING AND ITS APPLICATIONS Active ES2478690B1 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
ES201231962A ES2478690B1 (en) 2012-12-18 2012-12-18 PHENOLIC EXTRACTS OF UNCARIA TOMENTOSA L. (CAT CLAW) CONTAINING PROCIANIDINS, PROPELARGONIDINS AND FLAVANOLIGNANS, PROCEDURE OF OBTAINING AND ITS APPLICATIONS
PCT/ES2013/070876 WO2014096488A1 (en) 2012-12-18 2013-12-12 Phenolic extracts of uncaria tomentosa l. (cat's claw) containing procyanidins, propelargonidins and flavonolignans, method for the production thereof, and applications of same
CR20150334A CR20150334A (en) 2012-12-18 2015-06-23 PHENOLIC EXTRACTS OF TOMENTOUS UNCARIA (CAT CLAW) CONTAINING PROCIANIDINS, PROPELARGONIDINS AND FLAVANOLIGNANS, PROCEDURE OF OBTAINING AND ITS APPLICATIONS

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES201231962A ES2478690B1 (en) 2012-12-18 2012-12-18 PHENOLIC EXTRACTS OF UNCARIA TOMENTOSA L. (CAT CLAW) CONTAINING PROCIANIDINS, PROPELARGONIDINS AND FLAVANOLIGNANS, PROCEDURE OF OBTAINING AND ITS APPLICATIONS

Publications (2)

Publication Number Publication Date
ES2478690A1 ES2478690A1 (en) 2014-07-22
ES2478690B1 true ES2478690B1 (en) 2015-05-05

Family

ID=50977644

Family Applications (1)

Application Number Title Priority Date Filing Date
ES201231962A Active ES2478690B1 (en) 2012-12-18 2012-12-18 PHENOLIC EXTRACTS OF UNCARIA TOMENTOSA L. (CAT CLAW) CONTAINING PROCIANIDINS, PROPELARGONIDINS AND FLAVANOLIGNANS, PROCEDURE OF OBTAINING AND ITS APPLICATIONS

Country Status (3)

Country Link
CR (1) CR20150334A (en)
ES (1) ES2478690B1 (en)
WO (1) WO2014096488A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104622757B (en) * 2015-02-11 2018-03-16 广州赛莱拉干细胞科技股份有限公司 A kind of extracting method of Apple cell extract and its application
CN106046014B (en) * 2016-05-26 2018-05-01 天津市科曼思特医药科技发展有限公司 A kind of preparation method and applications of cinchonain Ib
CN113149857B (en) * 2021-05-10 2021-10-29 山东中医药大学 Amide compound and preparation method and application thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030017998A1 (en) * 1997-05-16 2003-01-23 Snow Alan D. Proanthocyanidins for the treatment of amyloid and alpha-synuclein diseases
JP2001131079A (en) * 1999-11-04 2001-05-15 Noevir Co Ltd Skin preparation for external use
CA2427661C (en) * 2000-11-03 2013-05-28 Proteotech, Inc. Methods of isolating amyloid-inhibiting compounds and use of compounds isolated from uncaria tomentosa and related plants
CA2499549C (en) * 2002-10-11 2012-01-24 Proteotech, Inc. Isolation, purification and synthesis of procyanidin b2 and uses thereof
BRPI0403688A (en) * 2004-09-01 2006-05-02 Herbarium Lab Botan Ltda topical herbal compound for treatment of herpes

Also Published As

Publication number Publication date
CR20150334A (en) 2015-11-30
ES2478690A1 (en) 2014-07-22
WO2014096488A1 (en) 2014-06-26

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