ES2422563A1 - Injectable pharmaceutical composition of ibuprofen and arginine, its preparation procedure, unit dosage form and use thereof (Machine-translation by Google Translate, not legally binding) - Google Patents

Injectable pharmaceutical composition of ibuprofen and arginine, its preparation procedure, unit dosage form and use thereof (Machine-translation by Google Translate, not legally binding)

Info

Publication number
ES2422563A1
ES2422563A1 ES201200240A ES201200240A ES2422563A1 ES 2422563 A1 ES2422563 A1 ES 2422563A1 ES 201200240 A ES201200240 A ES 201200240A ES 201200240 A ES201200240 A ES 201200240A ES 2422563 A1 ES2422563 A1 ES 2422563A1
Authority
ES
Spain
Prior art keywords
ibuprofen
arginine
pharmaceutical composition
injectable pharmaceutical
translation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES201200240A
Other languages
Spanish (es)
Other versions
ES2422563B1 (en
Inventor
Menendez Nuria Sanz
Ruiz Angel Munoz
Fernando Martinez-Alzamora
Calvo Antonia Gomez
Martinez Jose Miguel Rizo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Farmalider SA
Original Assignee
Farmalider SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Farmalider SA filed Critical Farmalider SA
Priority to ES201200240A priority Critical patent/ES2422563B1/en
Publication of ES2422563A1 publication Critical patent/ES2422563A1/en
Application granted granted Critical
Publication of ES2422563B1 publication Critical patent/ES2422563B1/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Dermatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Injectable pharmaceutical composition of ibuprofen and arginine, its preparation procedure, unit dosage form and use thereof. The present invention relates to an injectable pharmaceutical composition of ibuprofen and arginine. In particular, it is an aqueous solution containing ibuprofen arginate and an isotonizing agent, which is especially suitable for intravenous administration. The present invention also relates to a method for the preparation of said composition, as well as to its use for the treatment of moderate acute pain, especially after surgery when oral administration is not adequate, inflammation and/or fever. (Machine-translation by Google Translate, not legally binding)
ES201200240A 2012-03-08 2012-03-08 Injectable pharmaceutical composition of ibuprofen and arginine, its preparation procedure, unit dosage form and use thereof Active ES2422563B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
ES201200240A ES2422563B1 (en) 2012-03-08 2012-03-08 Injectable pharmaceutical composition of ibuprofen and arginine, its preparation procedure, unit dosage form and use thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES201200240A ES2422563B1 (en) 2012-03-08 2012-03-08 Injectable pharmaceutical composition of ibuprofen and arginine, its preparation procedure, unit dosage form and use thereof

Publications (2)

Publication Number Publication Date
ES2422563A1 true ES2422563A1 (en) 2013-09-12
ES2422563B1 ES2422563B1 (en) 2014-06-10

Family

ID=49034347

Family Applications (1)

Application Number Title Priority Date Filing Date
ES201200240A Active ES2422563B1 (en) 2012-03-08 2012-03-08 Injectable pharmaceutical composition of ibuprofen and arginine, its preparation procedure, unit dosage form and use thereof

Country Status (1)

Country Link
ES (1) ES2422563B1 (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104622816A (en) * 2015-01-04 2015-05-20 济南东方开元医药新技术有限公司 Ibuprofenlyophilized powder composition and preparation method
WO2018025128A1 (en) * 2016-08-02 2018-02-08 Jamil Irfan Stable ibuprofen injectable composition

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5200558A (en) * 1989-10-17 1993-04-06 Merck & Co., Inc. S(+)-ibuprofen-L-amino acid and S(+)-ibuprofen-D-amino acid as onset-hastened enhanced analgesics
WO1995000134A1 (en) * 1993-06-21 1995-01-05 Zambon Group S.P.A. Liquid pharmaceutical composition for oral use containing 2-(4-isobutylphenyl)propionic acid
US6342530B1 (en) * 2000-11-14 2002-01-29 Farmacon-Il, Llc Composition and method for parenteral administration of ibuprofen d,l- or l-lysine salt
WO2003039532A1 (en) * 2001-11-02 2003-05-15 Cumberland Pharmaceuticals Inc. Pharmaceutical composition of 2-(4-isobutylphenyl) propionic acid
FR2950533A1 (en) * 2009-09-28 2011-04-01 Maco Pharma Sa LIQUID FORMULATION, STABLE, READY TO USE KETOPROFEN
CN102100686A (en) * 2009-12-21 2011-06-22 北京润德康医药技术有限公司 Medicinal composition containing ibuprofen and arginine and preparation method and application thereof
CN102266285A (en) * 2010-06-03 2011-12-07 沈阳双鼎科技有限公司 Low excitant ibuprofen injection

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5200558A (en) * 1989-10-17 1993-04-06 Merck & Co., Inc. S(+)-ibuprofen-L-amino acid and S(+)-ibuprofen-D-amino acid as onset-hastened enhanced analgesics
WO1995000134A1 (en) * 1993-06-21 1995-01-05 Zambon Group S.P.A. Liquid pharmaceutical composition for oral use containing 2-(4-isobutylphenyl)propionic acid
US6342530B1 (en) * 2000-11-14 2002-01-29 Farmacon-Il, Llc Composition and method for parenteral administration of ibuprofen d,l- or l-lysine salt
WO2003039532A1 (en) * 2001-11-02 2003-05-15 Cumberland Pharmaceuticals Inc. Pharmaceutical composition of 2-(4-isobutylphenyl) propionic acid
FR2950533A1 (en) * 2009-09-28 2011-04-01 Maco Pharma Sa LIQUID FORMULATION, STABLE, READY TO USE KETOPROFEN
CN102100686A (en) * 2009-12-21 2011-06-22 北京润德康医药技术有限公司 Medicinal composition containing ibuprofen and arginine and preparation method and application thereof
CN102266285A (en) * 2010-06-03 2011-12-07 沈阳双鼎科技有限公司 Low excitant ibuprofen injection

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Theory and Practice of Contemporary Pharmaceutics; Edited by Tapash K. Ghosh y Bhaskara R. Jasti, CRC Press LLC, 2005, ISBN 0-415-28863-0; páginas 396-398, 406-407. *

Cited By (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104622816A (en) * 2015-01-04 2015-05-20 济南东方开元医药新技术有限公司 Ibuprofenlyophilized powder composition and preparation method
CN104622816B (en) * 2015-01-04 2017-05-10 济南东方开元医药新技术有限公司 Ibuprofenlyophilized powder composition and preparation method
WO2018025128A1 (en) * 2016-08-02 2018-02-08 Jamil Irfan Stable ibuprofen injectable composition
CN109843266A (en) * 2016-08-02 2019-06-04 安巴知识产权有限公司 Stable brufen injectable composition
KR20190062385A (en) * 2016-08-02 2019-06-05 암바 아이피 리미티드 Composition for stable ibuprofen administration
US20190183823A1 (en) * 2016-08-02 2019-06-20 Ambah Ip Limited Stable ibuprofen injectable composition
JP2019523292A (en) * 2016-08-02 2019-08-22 アンバー アイピー リミテッド Stable composition for ibuprofen injection formulation
AU2017307313B2 (en) * 2016-08-02 2021-09-09 Ambah Ip Limited Stable ibuprofen injectable composition
JP2022089867A (en) * 2016-08-02 2022-06-16 アンバー アイピー リミテッド Stable composition for injectable formulation containing ibuprofen
US11541024B2 (en) * 2016-08-02 2023-01-03 Ambah Ip Limited Stable ibuprofen injectable composition
CN109843266B (en) * 2016-08-02 2023-08-11 安巴知识产权有限公司 Stable ibuprofen injection composition
JP7386080B2 (en) 2016-08-02 2023-11-24 アンバー アイピー リミテッド Stable ibuprofen injection composition
JP7542028B2 (en) 2016-08-02 2024-08-29 アンバー アイピー リミテッド Composition for stable ibuprofen injection formulation

Also Published As

Publication number Publication date
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