ES2392994B1 - Dendrimeros carbosilanos catiónicos obtenidos mediante "click chemistry", su preparación y sus usos - Google Patents

Dendrimeros carbosilanos catiónicos obtenidos mediante "click chemistry", su preparación y sus usos Download PDF

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Publication number
ES2392994B1
ES2392994B1 ES201130804A ES201130804A ES2392994B1 ES 2392994 B1 ES2392994 B1 ES 2392994B1 ES 201130804 A ES201130804 A ES 201130804A ES 201130804 A ES201130804 A ES 201130804A ES 2392994 B1 ES2392994 B1 ES 2392994B1
Authority
ES
Spain
Prior art keywords
dendrimeros
catiónic
carbosilan
preparation
click chemistry
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
ES201130804A
Other languages
English (en)
Other versions
ES2392994A1 (es
Inventor
Francisco Javier De La Mata De La Mata
Rafael Gomez Ramirez
Eduardo Arnaiz Garrido
Sandra GARCIA GALLEGO
Jose Luis Copa Patiño
Juan Soliveri De Carranza
Jose Manuel HERNANDEZ ROS
Mª Angeles MUÑOZ-FERNANDEZ
Veronica BRIZ SEBASTIAN
Mª JESUS SERRAMIA LOBERA
Conchita TROS DE ILARDUYA
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Universidad de Navarra
Original Assignee
Universidad de Alcala de Henares UAH
Universidad de Navarra
Fundacion para la Investigacion Biomedica del Hospital Gregorio Marañon
Instituto Cientifico y Tecnologico de Navarra SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Universidad de Alcala de Henares UAH, Universidad de Navarra, Fundacion para la Investigacion Biomedica del Hospital Gregorio Marañon, Instituto Cientifico y Tecnologico de Navarra SA filed Critical Universidad de Alcala de Henares UAH
Priority to ES201130804A priority Critical patent/ES2392994B1/es
Publication of ES2392994A1 publication Critical patent/ES2392994A1/es
Application granted granted Critical
Publication of ES2392994B1 publication Critical patent/ES2392994B1/es
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/68Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
    • A61K47/6835Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site
    • A61K47/6883Polymer-drug antibody conjugates, e.g. mitomycin-dextran-Ab; DNA-polylysine-antibody complex or conjugate used for therapy
    • A61K47/6885Polymer-drug antibody conjugates, e.g. mitomycin-dextran-Ab; DNA-polylysine-antibody complex or conjugate used for therapy the conjugate or the polymer being a starburst, a dendrimer, a cascade
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D249/00Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/041,2,3-Triazoles; Hydrogenated 1,2,3-triazoles
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G83/00Macromolecular compounds not provided for in groups C08G2/00 - C08G81/00
    • C08G83/002Dendritic macromolecules
    • C08G83/003Dendrimers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Biotechnology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ES201130804A 2011-05-18 2011-05-18 Dendrimeros carbosilanos catiónicos obtenidos mediante "click chemistry", su preparación y sus usos Expired - Fee Related ES2392994B1 (es)

Priority Applications (1)

Application Number Priority Date Filing Date Title
ES201130804A ES2392994B1 (es) 2011-05-18 2011-05-18 Dendrimeros carbosilanos catiónicos obtenidos mediante "click chemistry", su preparación y sus usos

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES201130804A ES2392994B1 (es) 2011-05-18 2011-05-18 Dendrimeros carbosilanos catiónicos obtenidos mediante "click chemistry", su preparación y sus usos

Publications (2)

Publication Number Publication Date
ES2392994A1 ES2392994A1 (es) 2012-12-17
ES2392994B1 true ES2392994B1 (es) 2013-10-24

Family

ID=47227262

Family Applications (1)

Application Number Title Priority Date Filing Date
ES201130804A Expired - Fee Related ES2392994B1 (es) 2011-05-18 2011-05-18 Dendrimeros carbosilanos catiónicos obtenidos mediante "click chemistry", su preparación y sus usos

Country Status (1)

Country Link
ES (1) ES2392994B1 (es)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2265291B1 (es) * 2005-07-22 2008-03-01 Universidad De Alcala Nuevos dendrimeros carbosilanos, su preparacion y sus usos.

Also Published As

Publication number Publication date
ES2392994A1 (es) 2012-12-17

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