ES2363368T5 - Utilización de vitamina K para revertir la calcificación de los vasos sanguíneos - Google Patents
Utilización de vitamina K para revertir la calcificación de los vasos sanguíneos Download PDFInfo
- Publication number
- ES2363368T5 ES2363368T5 ES06076172T ES06076172T ES2363368T5 ES 2363368 T5 ES2363368 T5 ES 2363368T5 ES 06076172 T ES06076172 T ES 06076172T ES 06076172 T ES06076172 T ES 06076172T ES 2363368 T5 ES2363368 T5 ES 2363368T5
- Authority
- ES
- Spain
- Prior art keywords
- vitamin
- calcification
- reverse
- failure
- cardiovascular disorders
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 229930003448 Vitamin K Natural products 0.000 title abstract 4
- SHUZOJHMOBOZST-UHFFFAOYSA-N phylloquinone Natural products CC(C)CCCCC(C)CCC(C)CCCC(=CCC1=C(C)C(=O)c2ccccc2C1=O)C SHUZOJHMOBOZST-UHFFFAOYSA-N 0.000 title abstract 4
- 235000019168 vitamin K Nutrition 0.000 title abstract 4
- 239000011712 vitamin K Substances 0.000 title abstract 4
- 150000003721 vitamin K derivatives Chemical class 0.000 title abstract 4
- 229940046010 vitamin k Drugs 0.000 title abstract 4
- 210000004204 blood vessel Anatomy 0.000 title abstract 2
- 230000002308 calcification Effects 0.000 title abstract 2
- 208000024172 Cardiovascular disease Diseases 0.000 abstract 2
- 206010019280 Heart failures Diseases 0.000 abstract 2
- 206010002383 Angina Pectoris Diseases 0.000 abstract 1
- 206010003210 Arteriosclerosis Diseases 0.000 abstract 1
- 206010020772 Hypertension Diseases 0.000 abstract 1
- 208000007177 Left Ventricular Hypertrophy Diseases 0.000 abstract 1
- 206010024119 Left ventricular failure Diseases 0.000 abstract 1
- 206010037368 Pulmonary congestion Diseases 0.000 abstract 1
- 208000034189 Sclerosis Diseases 0.000 abstract 1
- 230000032683 aging Effects 0.000 abstract 1
- 208000011775 arteriosclerosis disease Diseases 0.000 abstract 1
- 210000001367 artery Anatomy 0.000 abstract 1
- 230000001684 chronic effect Effects 0.000 abstract 1
- 238000009472 formulation Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 208000010125 myocardial infarction Diseases 0.000 abstract 1
- 235000016709 nutrition Nutrition 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
- A61K31/593—9,10-Secocholestane derivatives, e.g. cholecalciferol, i.e. vitamin D3
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/15—Vitamins
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/15—Vitamins
- A23L33/155—Vitamins A or D
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/12—Ketones
- A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Heart & Thoracic Surgery (AREA)
- Food Science & Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Cardiology (AREA)
- Epidemiology (AREA)
- Polymers & Plastics (AREA)
- Mycology (AREA)
- Nutrition Science (AREA)
- Organic Chemistry (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US144853 | 2005-06-03 | ||
US11/144,853 US9364447B2 (en) | 2002-08-30 | 2005-06-03 | Compositions for treating or preventing cardiovascular disease |
Publications (2)
Publication Number | Publication Date |
---|---|
ES2363368T3 ES2363368T3 (es) | 2011-08-02 |
ES2363368T5 true ES2363368T5 (es) | 2015-03-02 |
Family
ID=36940251
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES06076172T Active ES2363368T5 (es) | 2005-06-03 | 2006-06-06 | Utilización de vitamina K para revertir la calcificación de los vasos sanguíneos |
Country Status (8)
Country | Link |
---|---|
EP (1) | EP1728507B2 (es) |
AT (1) | ATE501715T1 (es) |
DE (1) | DE602006020658D1 (es) |
DK (1) | DK1728507T4 (es) |
ES (1) | ES2363368T5 (es) |
PL (1) | PL1728507T3 (es) |
PT (1) | PT1728507E (es) |
SI (1) | SI1728507T1 (es) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB0220182D0 (en) | 2002-08-30 | 2002-10-09 | Cardiovascular Res Inst Maastr | Organic compounds |
EP2060256A1 (en) | 2007-11-16 | 2009-05-20 | Gnosis S.p.A. | Pharmaceutical and nutraceutical compositions based on menaquinols |
DE102010015242A1 (de) * | 2010-04-15 | 2011-10-20 | Fresenius Medical Care Deutschland Gmbh | Kombination aus Vitamin K und Nikotinamid |
IT1402330B1 (it) * | 2010-09-03 | 2013-08-30 | Poli | Integratore alimentare |
US11357250B2 (en) | 2016-08-15 | 2022-06-14 | Summit Innovation Labs LLC | Treatment and prevention of diabetes and obesity |
US11344575B2 (en) * | 2016-08-15 | 2022-05-31 | Summit Innovation Labs, LLC | Vascular calcification prevention and treatment |
CA3085749A1 (en) * | 2017-12-14 | 2019-06-20 | Calroy Health Sciences, Llc | Methods to stabilize and reverse atherosclerotic lesions by sulfated polysaccharides |
US11911349B2 (en) | 2018-03-30 | 2024-02-27 | Nattopharma As | Rapidly improving vascular conditions by administering vitamin K |
AU2019282420A1 (en) | 2018-06-08 | 2021-01-07 | Epizon Pharma, Inc. | Methods and compositions for preventing or treating tissue calcification |
KR20210018422A (ko) | 2018-06-08 | 2021-02-17 | 에피존 파마 인코포레이티드 | 저항성칼슘형성의 예방 또는 치료를 위한 방법 및 조성물 |
EP3937916A1 (en) | 2019-03-11 | 2022-01-19 | Kaydence Pharma AS | Rapidly improving endothelial function, reducing arterial stiffness and reversing calcification of blood vessels by administering vitamin k |
CN110122866A (zh) * | 2019-05-31 | 2019-08-16 | 广东双骏生物科技有限公司 | 一种慢性肾脏病血管钙化的特殊医学用途食品及制备方法 |
CN114748486A (zh) * | 2022-03-25 | 2022-07-15 | 南京盛德生物科技研究院有限公司 | 一种含有维生素k2改善心血管钙化的药物组合物及其制备方法与应用 |
WO2023232643A1 (en) | 2022-05-31 | 2023-12-07 | Region Syddanmark | Vitamin k2 for use in treatment of coronary artery calcification |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0679394B1 (en) † | 1994-04-28 | 1998-01-14 | Eisai Co., Ltd. | Menatetronome derivative as antiarteriosclerotic agent |
DE60128179T2 (de) | 2000-05-12 | 2008-01-10 | Nattopharma Asa | Nahrungsmittel enthaltend Vitamin k2 |
WO2003013420A2 (en) † | 2001-08-03 | 2003-02-20 | Vitak Bv | Isoprenyl derivatives and their use in the treatment and prevention of osteoporosis and cardiovascular calcification |
GB0220182D0 (en) † | 2002-08-30 | 2002-10-09 | Cardiovascular Res Inst Maastr | Organic compounds |
-
2006
- 2006-06-06 ES ES06076172T patent/ES2363368T5/es active Active
- 2006-06-06 AT AT06076172T patent/ATE501715T1/de active
- 2006-06-06 DE DE602006020658T patent/DE602006020658D1/de active Active
- 2006-06-06 PT PT06076172T patent/PT1728507E/pt unknown
- 2006-06-06 DK DK06076172.3T patent/DK1728507T4/en active
- 2006-06-06 SI SI200631032T patent/SI1728507T1/sl unknown
- 2006-06-06 EP EP06076172.3A patent/EP1728507B2/en active Active
- 2006-06-06 PL PL06076172T patent/PL1728507T3/pl unknown
Also Published As
Publication number | Publication date |
---|---|
DE602006020658D1 (de) | 2011-04-28 |
ATE501715T1 (de) | 2011-04-15 |
EP1728507A1 (en) | 2006-12-06 |
DK1728507T4 (en) | 2015-01-12 |
EP1728507B2 (en) | 2014-11-12 |
PT1728507E (pt) | 2011-05-27 |
DK1728507T3 (da) | 2011-05-23 |
EP1728507B1 (en) | 2011-03-16 |
PL1728507T3 (pl) | 2011-09-30 |
SI1728507T1 (sl) | 2011-07-29 |
ES2363368T3 (es) | 2011-08-02 |
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