ES2343880B8 - PYRIDOTIENOTRIAZINS AS ANTIANGIOGENIC COMPOUNDS. - Google Patents

PYRIDOTIENOTRIAZINS AS ANTIANGIOGENIC COMPOUNDS. Download PDF

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Publication number
ES2343880B8
ES2343880B8 ES200950054A ES200950054A ES2343880B8 ES 2343880 B8 ES2343880 B8 ES 2343880B8 ES 200950054 A ES200950054 A ES 200950054A ES 200950054 A ES200950054 A ES 200950054A ES 2343880 B8 ES2343880 B8 ES 2343880B8
Authority
ES
Spain
Prior art keywords
pyridotienotriazins
pyridothienotriazines
antiangiogenic compounds
antiangiogenic
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES200950054A
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Spanish (es)
Other versions
ES2343880A1 (en
ES2343880B1 (en
Inventor
Ana Rodriguez Quesada
Beatriz Martinez Poveda
Miguel Angel Medina Torres
Ramon Muñoz Chápuli
Antonio Fernández Medarde
Jose Maria Quintela Lopez
Ricardo Jesus Riguera Vega
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Universidad de Malaga
Original Assignee
Universidad de Malaga
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
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Publication of ES2343880A1 publication Critical patent/ES2343880A1/en
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Publication of ES2343880B1 publication Critical patent/ES2343880B1/en
Publication of ES2343880B8 publication Critical patent/ES2343880B8/en
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/53—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D495/14—Ortho-condensed systems

Abstract

Piridotienotriazinas como compuestos antiangiogénicos.Pyridothienotriazines as compounds antiangiogenic

La presente invención se refiere a derivados de piridotienotriazinas con actividad antioangiogénica y su uso en la preparación de composiciones farmacéuticas o medicamentos para el tratamiento de enfermedades es las que está implicado el proceso de la angiogénesis, como son cáncer, obesidad, retinopatías diabáticas, degeneración macular, hemangiomas, artritis, psoriasis y aterosclerosis.The present invention relates to derivatives of pyridothienotriazines with antioangiogenic activity and its use in preparation of pharmaceutical compositions or medicaments for Disease treatment is what the process of angiogenesis, such as cancer, obesity, diabetic retinopathies, macular degeneration, hemangiomas, arthritis, psoriasis and atherosclerosis

ES200950054A 2007-05-10 2008-05-07 PYRIDOTIENOTRIAZINS AS ANTIANGIOGENIC COMPOUNDS. Active ES2343880B8 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP073801333 2007-05-10
EP07380133 2007-05-10
EP07380133 2007-05-10

Publications (3)

Publication Number Publication Date
ES2343880A1 ES2343880A1 (en) 2010-08-11
ES2343880B1 ES2343880B1 (en) 2011-06-16
ES2343880B8 true ES2343880B8 (en) 2011-12-01

Family

ID=40001724

Family Applications (1)

Application Number Title Priority Date Filing Date
ES200950054A Active ES2343880B8 (en) 2007-05-10 2008-05-07 PYRIDOTIENOTRIAZINS AS ANTIANGIOGENIC COMPOUNDS.

Country Status (2)

Country Link
ES (1) ES2343880B8 (en)
WO (1) WO2008139009A1 (en)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL158899A0 (en) * 2001-05-23 2004-05-12 Pharmaceutical compositions for inhibiting angiogenesis containing oleuropein and derivatives thereof

Also Published As

Publication number Publication date
WO2008139009A1 (en) 2008-11-20
ES2343880A1 (en) 2010-08-11
ES2343880B1 (en) 2011-06-16

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