ES2328328A1 - Polimorfo alfa de una pirazolina sustituida, su preparacion y su uso como medicamento - Google Patents
Polimorfo alfa de una pirazolina sustituida, su preparacion y su uso como medicamento Download PDFInfo
- Publication number
- ES2328328A1 ES2328328A1 ES200800067A ES200800067A ES2328328A1 ES 2328328 A1 ES2328328 A1 ES 2328328A1 ES 200800067 A ES200800067 A ES 200800067A ES 200800067 A ES200800067 A ES 200800067A ES 2328328 A1 ES2328328 A1 ES 2328328A1
- Authority
- ES
- Spain
- Prior art keywords
- preparation
- polymorph
- medicaments
- alpha
- substituted pyrazoline
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/06—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
- A61K31/4155—1,2-Diazoles non condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Diabetes (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Hematology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Obesity (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Child & Adolescent Psychology (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Polimorfo alfa de una pirazolina sustituida, su preparación y su uso como medicamento. La presente invención se refiere al polimorfo a de la (R)-N-piperidinil-5-(4-clorofenil)-1-(2,4-diclorofenil)-4,5-dihidro-1H-pirazol-3-carboxamida, a procedimientos para su preparación, a medicamentos que comprenden este compuesto, así como a su uso para preparar un medicamento para el tratamiento de seres humanos y animales.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP07384003A EP1944293A1 (en) | 2007-01-15 | 2007-01-15 | Alpha-Polymorph of a substituted pyrazoline, its preparation and use as medicaments |
Publications (2)
Publication Number | Publication Date |
---|---|
ES2328328A1 true ES2328328A1 (es) | 2009-11-11 |
ES2328328B1 ES2328328B1 (es) | 2010-05-28 |
Family
ID=38008088
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES200800067A Expired - Fee Related ES2328328B1 (es) | 2007-01-15 | 2008-01-11 | Polimorfo alfa de una pirazolina sustituida, su preparacion y su uso como medicamento |
Country Status (2)
Country | Link |
---|---|
EP (1) | EP1944293A1 (es) |
ES (1) | ES2328328B1 (es) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2314578A1 (en) * | 2009-10-13 | 2011-04-27 | Esteve Química, S.A. | Cinchonidine salt of (4S,5S)-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-4,5-dihydro-1H-pyrazole-3-carboxylic acid, useful as intermediate in the preparation of cannabinoid CB1 neutral antagonists |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2005077911A1 (en) * | 2004-02-17 | 2005-08-25 | Laboratorios Del Dr. Esteve S.A. | Substituted pyrazoline compounds, their preparation and use as medicaments |
EP1757588A1 (en) * | 2005-07-29 | 2007-02-28 | Laboratorios Del Dr. Esteve, S.A. | Polymorph of N-Piperidinyl-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4,5-dihydro-1H-pyrazole-3-carboxamide and its use as a cannabinoid receptor modulator |
-
2007
- 2007-01-15 EP EP07384003A patent/EP1944293A1/en not_active Withdrawn
-
2008
- 2008-01-11 ES ES200800067A patent/ES2328328B1/es not_active Expired - Fee Related
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2005077911A1 (en) * | 2004-02-17 | 2005-08-25 | Laboratorios Del Dr. Esteve S.A. | Substituted pyrazoline compounds, their preparation and use as medicaments |
EP1757588A1 (en) * | 2005-07-29 | 2007-02-28 | Laboratorios Del Dr. Esteve, S.A. | Polymorph of N-Piperidinyl-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4,5-dihydro-1H-pyrazole-3-carboxamide and its use as a cannabinoid receptor modulator |
Also Published As
Publication number | Publication date |
---|---|
ES2328328B1 (es) | 2010-05-28 |
EP1944293A1 (en) | 2008-07-16 |
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Legal Events
Date | Code | Title | Description |
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Date of ref document: 20091111 Kind code of ref document: A1 |
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FD2A | Announcement of lapse in spain |
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