ES2265201A1 - Nuevas dianas terapeuticas y su uso para el tratamiento del dolor. - Google Patents

Nuevas dianas terapeuticas y su uso para el tratamiento del dolor. Download PDF

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Publication number
ES2265201A1
ES2265201A1 ES200301768A ES200301768A ES2265201A1 ES 2265201 A1 ES2265201 A1 ES 2265201A1 ES 200301768 A ES200301768 A ES 200301768A ES 200301768 A ES200301768 A ES 200301768A ES 2265201 A1 ES2265201 A1 ES 2265201A1
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ES
Spain
Prior art keywords
interaction
products
thermoreceptor
snapin
therapeutic targets
Prior art date
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Granted
Application number
ES200301768A
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English (en)
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ES2265201B1 (es
Inventor
Palao Maria Cruz Morenilla
Cases Rosa Maria Planells
Sanz Nuria Garcia
Montiel Antonio Vicente Ferrer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Universidad Miguel Hernandez de Elche UMH
Original Assignee
Universidad Miguel Hernandez de Elche UMH
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Publication date
Application filed by Universidad Miguel Hernandez de Elche UMH filed Critical Universidad Miguel Hernandez de Elche UMH
Priority to ES200301768A priority Critical patent/ES2265201B1/es
Publication of ES2265201A1 publication Critical patent/ES2265201A1/es
Application granted granted Critical
Publication of ES2265201B1 publication Critical patent/ES2265201B1/es
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Nuevas dianas terapéuticas y su uso para el tratamiento del dolor. Complejos macromoleculares implicados en la etiología del dolor, caracterizados por estar formados por la interacción de las proteínas vesiculares snapin y/o cualquiera de las isoformas de sinaptotagmina I, II o IX con el termorreceptor TRPV1, y su uso como dianas terapéuticas para el cribado de quimiotecas naturales o sintéticas y para la identificación de compuestos con actividad analgésica y/o antiinflamatoria.
ES200301768A 2003-07-25 2003-07-25 Nuevas dianas terapeuticas y su uso para el tratamiento del dolor. Expired - Fee Related ES2265201B1 (es)

Priority Applications (1)

Application Number Priority Date Filing Date Title
ES200301768A ES2265201B1 (es) 2003-07-25 2003-07-25 Nuevas dianas terapeuticas y su uso para el tratamiento del dolor.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES200301768A ES2265201B1 (es) 2003-07-25 2003-07-25 Nuevas dianas terapeuticas y su uso para el tratamiento del dolor.

Publications (2)

Publication Number Publication Date
ES2265201A1 true ES2265201A1 (es) 2007-02-01
ES2265201B1 ES2265201B1 (es) 2008-01-01

Family

ID=38290796

Family Applications (1)

Application Number Title Priority Date Filing Date
ES200301768A Expired - Fee Related ES2265201B1 (es) 2003-07-25 2003-07-25 Nuevas dianas terapeuticas y su uso para el tratamiento del dolor.

Country Status (1)

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ES (1) ES2265201B1 (es)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009112615A1 (es) 2008-03-11 2009-09-17 Fundación De La Comunidad Valenciana, Centro De Investigación Principe Felipe Composición farmacéutica para inhibir el factor de transcripción inducible por hipoxia. moduladores de procesos patológicos de angiogénesis, oncogénesis, inflamación, apoptosis y terapia celular

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998036081A2 (en) * 1997-02-13 1998-08-20 Memorial Sloan-Kettering Cancer Center Hybrid molecules for optically detecting changes in cellular microenvironments

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998036081A2 (en) * 1997-02-13 1998-08-20 Memorial Sloan-Kettering Cancer Center Hybrid molecules for optically detecting changes in cellular microenvironments

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
GARCIA-MARTINEZ, C. et al. "Attenuation of thermal nociception and hyperalgesia by VR1 blockers". PNAS. 19.02.2002. Vol. 99, n‘ 4, pàginas 2374-2379, todo el documento. *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009112615A1 (es) 2008-03-11 2009-09-17 Fundación De La Comunidad Valenciana, Centro De Investigación Principe Felipe Composición farmacéutica para inhibir el factor de transcripción inducible por hipoxia. moduladores de procesos patológicos de angiogénesis, oncogénesis, inflamación, apoptosis y terapia celular

Also Published As

Publication number Publication date
ES2265201B1 (es) 2008-01-01

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