ES219958A1 - A procedure for preparation of alcohiltiocolchiceinas (Machine-translation by Google Translate, not legally binding) - Google Patents

A procedure for preparation of alcohiltiocolchiceinas (Machine-translation by Google Translate, not legally binding)

Info

Publication number
ES219958A1
ES219958A1 ES0219958A ES219958A ES219958A1 ES 219958 A1 ES219958 A1 ES 219958A1 ES 0219958 A ES0219958 A ES 0219958A ES 219958 A ES219958 A ES 219958A ES 219958 A1 ES219958 A1 ES 219958A1
Authority
ES
Spain
Prior art keywords
translation
solvent
machine
legally binding
google translate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES0219958A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Roussel Uclaf SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf SA filed Critical Roussel Uclaf SA
Publication of ES219958A1 publication Critical patent/ES219958A1/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20Carbocyclic rings
    • C07H15/24Condensed ring systems having three or more rings
    • C07H15/248Colchicine radicals, e.g. colchicosides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

A process for preparing thiocolchicein alkyl alcohol characterized in that the methyl mercaptan is reacted at room temperature or at a higher temperature (preferably between 20 and 50º c) on a tropolinic compound of the general formula ** (see formula) ** ( where r have the same meaning as in claim i and where the amino group can be acetylated or alkylated) in the presence of a third solvent without solvent and in the presence of a catalyst during the time necessary to replace the methoxy function of the tropolonic cycle by an sch <sub > 3 the mercaptan and eventually the solvent are separated and the thioderivative is purified by fractional crystallization or chromatography. (Machine-translation by Google Translate, not legally binding)
ES0219958A 1954-02-10 1955-02-05 A procedure for preparation of alcohiltiocolchiceinas (Machine-translation by Google Translate, not legally binding) Expired ES219958A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR1099138T 1954-02-10
FR663208 1954-02-10

Publications (1)

Publication Number Publication Date
ES219958A1 true ES219958A1 (en) 1955-04-01

Family

ID=9619620

Family Applications (1)

Application Number Title Priority Date Filing Date
ES0219958A Expired ES219958A1 (en) 1954-02-10 1955-02-05 A procedure for preparation of alcohiltiocolchiceinas (Machine-translation by Google Translate, not legally binding)

Country Status (2)

Country Link
ES (1) ES219958A1 (en)
FR (1) FR1099138A (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE68919025T2 (en) * 1988-08-24 1995-03-02 Advance Biofactures Corp 3-demethylthiocolchicine carbonates and N-acyl analogs.

Also Published As

Publication number Publication date
FR1099138A (en) 1955-08-30

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