ES2194083T3 - Utilizacion en una composicion como activador y/o estabilizador de ciclooxigenasa de al menos un derivado de pirimidina sustituido en 6. - Google Patents
Utilizacion en una composicion como activador y/o estabilizador de ciclooxigenasa de al menos un derivado de pirimidina sustituido en 6.Info
- Publication number
- ES2194083T3 ES2194083T3 ES96400601T ES96400601T ES2194083T3 ES 2194083 T3 ES2194083 T3 ES 2194083T3 ES 96400601 T ES96400601 T ES 96400601T ES 96400601 T ES96400601 T ES 96400601T ES 2194083 T3 ES2194083 T3 ES 2194083T3
- Authority
- ES
- Spain
- Prior art keywords
- composition
- activator
- stabilizer
- replaced
- cycloxygenase
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/44—Oxidoreductases (1)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
- A61K8/4953—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom containing pyrimidine ring derivatives, e.g. minoxidil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/004—Aftersun preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q7/00—Preparations for affecting hair growth
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/74—Biological properties of particular ingredients
- A61K2800/75—Anti-irritant
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Dermatology (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Birds (AREA)
- Gerontology & Geriatric Medicine (AREA)
- Gastroenterology & Hepatology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cosmetics (AREA)
Abstract
LA INVENCION SE REFIERE A LA UTILIZACION EN UNA COMPOSICION COMO ACTIVADOR O ESTABILIZADOR DE CICLOOXIGENASA DE AL MENOS UN DERIVADO DE PIRIMIDINA SUSTITUIDO EN 6, MAS EN PARTICULAR DE AL MENOS UN DERIVADO DE PIRIMIDINA 3-OXIDO SUSTITUIDO EN 6. LA INVENCION SE REFIERE TAMBIEN A UNA COMPOSICION Y UN KIT QUE CONTIENE AL MENOS UNO DE LOS SUSTRATOS DE LA CICLOOXIGENASA Y AL MENOS UN DERIVADO DE PIRIMIDINA SUSTITUIDO EN 6, MAS EN PARTICULAR AL MENOS UN DERIVADO -3-OXIDO SUSTITUIDO EN 6 Y SU UTILIZACION. ESTA COMPOSICION O ESTE KIT PUEDEN ADEMAS CONTENER CICLOOXIGENASA.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9504049A FR2732597B1 (fr) | 1995-04-05 | 1995-04-05 | Utilisation dans une composition en tant qu'activateur et/ou stabilisateur de cyclooxygenase d'au moins un derive de pyrimidine substitue en 6 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2194083T3 true ES2194083T3 (es) | 2003-11-16 |
Family
ID=9477784
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES96400601T Expired - Lifetime ES2194083T3 (es) | 1995-04-05 | 1996-03-21 | Utilizacion en una composicion como activador y/o estabilizador de ciclooxigenasa de al menos un derivado de pirimidina sustituido en 6. |
Country Status (6)
Country | Link |
---|---|
US (1) | US5756092A (es) |
EP (1) | EP0736300B1 (es) |
CA (1) | CA2173544C (es) |
DE (1) | DE69626433T2 (es) |
ES (1) | ES2194083T3 (es) |
FR (1) | FR2732597B1 (es) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2753378B1 (fr) * | 1996-09-17 | 1998-11-20 | Oreal | Utilisation dans une composition en tant que stimulateur de tyrosinase d'au moins un derive de pyrimidine 3-oxyde, substitue en 6 |
DE19845202A1 (de) * | 1998-10-01 | 2000-04-06 | Wella Ag | Haarwuchsmittel |
FR2785802B1 (fr) * | 1998-11-12 | 2002-10-31 | Oreal | 2-amino, 4-alkylamino pyrimidine 3-oxydes comme anti-inflammatoires |
IT1318379B1 (it) * | 2000-03-08 | 2003-08-25 | Ira Srl | Composizione cosmetica o farmaceutica utile per inibire o ritardarel'alopecia umana mediante applicazione topica della composizione. |
WO2002012445A1 (en) * | 2000-08-07 | 2002-02-14 | Vanderbilt University | Detection of cox-2 activity and anandamide metabolites |
DE10202251A1 (de) * | 2002-01-21 | 2003-08-07 | Beiersdorf Ag | Kosmetische und/oder dermatologische Zubereitung |
US7314709B2 (en) * | 2002-08-06 | 2008-01-01 | Vanderbilt University | Compositions and methods for detecting and quantifying COX-2 activity by lipoamino acid metabolism |
ITMI20030369A1 (it) * | 2003-02-28 | 2004-09-01 | Farmaka Srl | Composizione cosmetica o farmaceutica ad uso topico per impedire o contrastare l'alopecia androgenetica. |
US7326717B2 (en) * | 2003-05-06 | 2008-02-05 | L'oreal | Pyrimidine n-oxide compounds for stimulating the growth of keratin fibers and/or reducing loss thereof |
US20060193804A1 (en) * | 2005-02-24 | 2006-08-31 | L'oreal | Haircare use of cyclic amine derivatives |
FR2920309B1 (fr) | 2007-08-28 | 2010-05-28 | Galderma Res & Dev | Utilisation de travoprost pour traiter la chute des cheveux |
FR2949052B1 (fr) | 2009-08-13 | 2015-03-27 | Oreal | Procede de traitement cosmetique du cuir chevelu. |
EP2838533B1 (en) | 2012-04-16 | 2017-10-04 | Case Western Reserve University | Compositions and methods of modulating 15-pgdh activity |
CA2927730A1 (en) | 2013-10-15 | 2015-05-07 | Case Western Reserve University | Compositions and methods of modulating short-chain dehydrogenase activity |
EP3548035A4 (en) | 2016-11-30 | 2020-07-22 | Case Western Reserve University | COMBINATIONS OF 15 PGDH INHIBITORS WITH CORTICOSTEROIDS AND / OR TNF INHIBITORS AND USES THEREOF |
WO2018145080A1 (en) | 2017-02-06 | 2018-08-09 | Case Western Reserve University | Compositions and methods of modulating short-chain dehydrogenase activity |
KR20210119954A (ko) | 2018-11-21 | 2021-10-06 | 케이스 웨스턴 리저브 유니버시티 | 단쇄 데히드로게나아제 활성을 조절하는 조성물 및 방법 |
US20230192717A1 (en) | 2020-05-20 | 2023-06-22 | Rodeo Therapeutics Corporation | Compositions and methods of modulating short-chain dehydrogenase activity |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR648488A (fr) * | 1928-02-07 | 1928-12-10 | Berten & Co G M B H | Dispositif pour la formation de corps de faible épaisseur, au moyen de matières plastiques, pâte de sucre en particulier |
FR2380775A1 (fr) * | 1977-02-22 | 1978-09-15 | Sederma Sarl | Composition " apres-epilation " favorisant un ralentissement progressif de la repousse des poils |
LU87308A1 (fr) * | 1988-08-01 | 1990-03-13 | Oreal | Nouveaux derives de diamino-2,4 pyrimidine oxyde-3 et leur utilisation pour le traitement et la prevention de la chute des cheveux |
ATE110718T1 (de) * | 1989-07-12 | 1994-09-15 | Oreal | Halogenierte pyrimidin-3-oxid-derivate, deren verwendung für die behandlung und die verhütung von haarausfall und für die wachstumsförderung von haaren. |
FR2662607B1 (fr) * | 1990-05-30 | 1992-08-28 | Oreal | Composition destinee a etre utilisee pour freiner la chute des cheveux et pour induire et stimuler leur croissance, contenant des derives d'alkyl-2 amino-4 (ou dialkyl-2-4) pyrimidine oxyde-3 . |
JPH06505239A (ja) * | 1991-01-31 | 1994-06-16 | ワーナー−ランバート・コンパニー | 抗炎症剤として有用な4,6−ジ−第三ブチル−5−ヒドロキシ−1,3−ピリミジンの置換されたヘテロアリール類似体 |
FR2677884B1 (fr) * | 1991-06-20 | 1993-07-09 | Oreal | Composition pour freiner la chute des cheveux a base de pyrimidines n-oxyde trisubstitues ou leurs derives sulfoconjugues, nouveaux composes pyrimidines n-oxyde ou leurs derives sulfoconjugues. |
FR2706896B1 (es) * | 1993-06-23 | 1996-04-12 | Caillot Jean Luc | |
FR2711060B1 (fr) * | 1993-10-13 | 1995-11-17 | Oreal | Procédé pour modifier la pousse des poils et/ou des cheveux et compositions utilisables à cet effet. |
-
1995
- 1995-04-05 FR FR9504049A patent/FR2732597B1/fr not_active Expired - Fee Related
-
1996
- 1996-03-21 EP EP96400601A patent/EP0736300B1/fr not_active Expired - Lifetime
- 1996-03-21 ES ES96400601T patent/ES2194083T3/es not_active Expired - Lifetime
- 1996-03-21 DE DE69626433T patent/DE69626433T2/de not_active Expired - Fee Related
- 1996-04-04 CA CA002173544A patent/CA2173544C/fr not_active Expired - Fee Related
- 1996-04-05 US US08/628,473 patent/US5756092A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
CA2173544A1 (fr) | 1996-10-06 |
FR2732597B1 (fr) | 1997-05-16 |
EP0736300A2 (fr) | 1996-10-09 |
US5756092A (en) | 1998-05-26 |
DE69626433D1 (de) | 2003-04-10 |
DE69626433T2 (de) | 2003-11-27 |
EP0736300A3 (fr) | 1996-11-06 |
EP0736300B1 (fr) | 2003-03-05 |
FR2732597A1 (fr) | 1996-10-11 |
CA2173544C (fr) | 1999-10-05 |
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