ES2189512T3 - Procedimiento para la obtencion estereoselectiva de ciclohexilcianhidrinas substituidas. - Google Patents

Procedimiento para la obtencion estereoselectiva de ciclohexilcianhidrinas substituidas.

Info

Publication number
ES2189512T3
ES2189512T3 ES99955299T ES99955299T ES2189512T3 ES 2189512 T3 ES2189512 T3 ES 2189512T3 ES 99955299 T ES99955299 T ES 99955299T ES 99955299 T ES99955299 T ES 99955299T ES 2189512 T3 ES2189512 T3 ES 2189512T3
Authority
ES
Spain
Prior art keywords
substituted
estereoselective
cyclhexilcianhydrines
procedure
obtaining
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES99955299T
Other languages
English (en)
Inventor
Franz Effenberger
Jurgen Roos
Reiner Fischer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer CropScience AG
Original Assignee
Bayer CropScience AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer CropScience AG filed Critical Bayer CropScience AG
Application granted granted Critical
Publication of ES2189512T3 publication Critical patent/ES2189512T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/002—Nitriles (-CN)
    • C12P13/004—Cyanohydrins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C07C255/45—Carboxylic acid nitriles having cyano groups bound to carbon atoms of rings other than six-membered aromatic rings
    • C07C255/46—Carboxylic acid nitriles having cyano groups bound to carbon atoms of rings other than six-membered aromatic rings to carbon atoms of non-condensed rings
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C12P41/002—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by oxidation/reduction reactions
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

Abstract

Procedimiento para la obtención estereoselectiva de ciclohexil-cianhidrinas de la fórmula (I)**(Fórmula)** en la que R significa alquilo, cicloalquilo (en el que está reemplazado en caso dado un grupo metileno por oxígeno), alcoxi, alqueniloxi, cicloalquiloxi, arilalquiloxi o arilo substituidos respectivamente en caso dado, caracterizado porque se hacen reaccionar ciclohexanonas de la fórmula (II)**(Fórmula)** en la que R tiene el significado anteriormente indicado, en presencia de una oxinitrilasa y, en caso dado, en presencia de un diluyente, con una fuente de cianuro.
ES99955299T 1998-06-02 1999-05-20 Procedimiento para la obtencion estereoselectiva de ciclohexilcianhidrinas substituidas. Expired - Lifetime ES2189512T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19824491A DE19824491A1 (de) 1998-06-02 1998-06-02 Verfahren zur stereoselektiven Herstellung von substituierten Cyclohexylcyanhydrinen

Publications (1)

Publication Number Publication Date
ES2189512T3 true ES2189512T3 (es) 2003-07-01

Family

ID=7869591

Family Applications (1)

Application Number Title Priority Date Filing Date
ES99955299T Expired - Lifetime ES2189512T3 (es) 1998-06-02 1999-05-20 Procedimiento para la obtencion estereoselectiva de ciclohexilcianhidrinas substituidas.

Country Status (9)

Country Link
US (1) US6465222B1 (es)
EP (1) EP1082449B1 (es)
JP (1) JP2002517203A (es)
AT (1) ATE233822T1 (es)
AU (1) AU4264799A (es)
DE (2) DE19824491A1 (es)
DK (1) DK1082449T3 (es)
ES (1) ES2189512T3 (es)
WO (1) WO1999063104A1 (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT408231B (de) * 1999-12-15 2001-09-25 Dsm Fine Chem Austria Gmbh Verfahren zur herstellung von optisch aktiven cyanhydrinen unter verwendung von r-oxynitrilase
AT411065B (de) * 2001-12-27 2003-09-25 Dsm Fine Chem Austria Gmbh Verfahren zur herstellung von heterocyclischen (r)- und (s)-cyanhydrinen
AT411064B (de) * 2001-12-27 2003-09-25 Dsm Fine Chem Austria Gmbh Verfahren zur herstellung von enantiomerenangereicherten cyanhydrinen unter verwendung von acetalen oder ketalen als substrate
US20090029179A1 (en) * 2007-05-14 2009-01-29 Fujifilm Corporation Two-liquid composition, hydrophilic composition and hydrophilic member

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4102327C1 (en) * 1991-01-26 1992-06-04 Degussa Ag, 6000 Frankfurt, De (R)-keto:cyanohydrin prepn. - by reacting ketone with prussic acid in organic solvent in presence of (R)-oxy:nitrilase; used in prepn. of alpha-hydroxy-alpha-(m)ethyl carboxylic acid
DE4139987C1 (es) * 1991-12-04 1993-04-15 Uwe Dr. 5303 Bornheim De Niedermeyer
DK0799894T3 (da) * 1996-02-09 2004-08-09 Degussa Fremgangsmåde til fremstilling af (S)-cyanhydriner

Also Published As

Publication number Publication date
DK1082449T3 (da) 2003-06-30
US6465222B1 (en) 2002-10-15
DE19824491A1 (de) 1999-12-09
EP1082449B1 (de) 2003-03-05
EP1082449A1 (de) 2001-03-14
WO1999063104A1 (de) 1999-12-09
JP2002517203A (ja) 2002-06-18
ATE233822T1 (de) 2003-03-15
DE59904461D1 (de) 2003-04-10
AU4264799A (en) 1999-12-20

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