ES2178938B1 - PROCEDURE FOR EMPTY PRODUCTION OF PHARMACEUTICAL PREPARATIONS OF CONTROLLED RELEASE AND / OR GASTRORRESISTENT. - Google Patents

PROCEDURE FOR EMPTY PRODUCTION OF PHARMACEUTICAL PREPARATIONS OF CONTROLLED RELEASE AND / OR GASTRORRESISTENT.

Info

Publication number
ES2178938B1
ES2178938B1 ES200002685A ES200002685A ES2178938B1 ES 2178938 B1 ES2178938 B1 ES 2178938B1 ES 200002685 A ES200002685 A ES 200002685A ES 200002685 A ES200002685 A ES 200002685A ES 2178938 B1 ES2178938 B1 ES 2178938B1
Authority
ES
Spain
Prior art keywords
procedure
controlled release
pharmaceutical preparations
pharmaceutical
gastrorresistent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
ES200002685A
Other languages
Spanish (es)
Other versions
ES2178938A1 (en
Inventor
Martin Luis Carvajal
Asensio Juan Carlos Asensio
Tirado Francisco J Sevilla
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Laboratorios Belmac SA
Original Assignee
Laboratorios Belmac SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratorios Belmac SA filed Critical Laboratorios Belmac SA
Priority to ES200002685A priority Critical patent/ES2178938B1/en
Publication of ES2178938A1 publication Critical patent/ES2178938A1/en
Application granted granted Critical
Publication of ES2178938B1 publication Critical patent/ES2178938B1/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Procedimiento para la producción a vacío de preparaciones farmacéuticas de liberación controlada y/o gastrorresistentes. Comprende la obtención de "pellets" y/o granulados de un principio activo mediante secado a vacío de una mezcla de dicho principio activo con uno o más excipientes farmacéuticamente aceptables destinados a impartir gastrorresistencia, llevándose a cabo dicho secado a vacío en una cuba giratoria provista de movimiento angular en la que se hace vacío al tiempo que se inyecta aire comprimido y/o nitrógeno en proporciones reducidas. Los pellets y/o granulados obtenidos tienen un tamaño de partícula comprendido entre 200 y 1000 {mi}. El procedimiento es especialmente adecuado para principios activos tales como omeprazol, diclofenaco, aspirina e ibuprofeno. El procedimiento tiene aplicación en el sector farmacéutico, en especial farmacéutico-galénico.Procedure for the vacuum production of pharmaceutical preparations of controlled release and / or gastro-resistant. It comprises obtaining "pellets" and / or granules of an active principle by vacuum drying a mixture of said active principle with one or more pharmaceutically acceptable excipients intended to impart gastro-resistance, said vacuum drying being carried out in a rotating bowl provided angular movement in which it is empty while compressed air and / or nitrogen are injected in reduced proportions. The pellets and / or granules obtained have a particle size between 200 and 1000 {mi}. The procedure is especially suitable for active ingredients such as omeprazole, diclofenac, aspirin and ibuprofen. The procedure has application in the pharmaceutical sector, especially pharmaceutical-Galenic.

ES200002685A 2000-11-07 2000-11-07 PROCEDURE FOR EMPTY PRODUCTION OF PHARMACEUTICAL PREPARATIONS OF CONTROLLED RELEASE AND / OR GASTRORRESISTENT. Expired - Fee Related ES2178938B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
ES200002685A ES2178938B1 (en) 2000-11-07 2000-11-07 PROCEDURE FOR EMPTY PRODUCTION OF PHARMACEUTICAL PREPARATIONS OF CONTROLLED RELEASE AND / OR GASTRORRESISTENT.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES200002685A ES2178938B1 (en) 2000-11-07 2000-11-07 PROCEDURE FOR EMPTY PRODUCTION OF PHARMACEUTICAL PREPARATIONS OF CONTROLLED RELEASE AND / OR GASTRORRESISTENT.

Publications (2)

Publication Number Publication Date
ES2178938A1 ES2178938A1 (en) 2003-01-01
ES2178938B1 true ES2178938B1 (en) 2003-12-16

Family

ID=8495575

Family Applications (1)

Application Number Title Priority Date Filing Date
ES200002685A Expired - Fee Related ES2178938B1 (en) 2000-11-07 2000-11-07 PROCEDURE FOR EMPTY PRODUCTION OF PHARMACEUTICAL PREPARATIONS OF CONTROLLED RELEASE AND / OR GASTRORRESISTENT.

Country Status (1)

Country Link
ES (1) ES2178938B1 (en)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3511900A (en) * 1967-08-22 1970-05-12 Ciba Geigy Corp Granulating process
JPS6168133A (en) * 1984-09-08 1986-04-08 Shinjiro Tsuji Granulating method
JPS6186913A (en) * 1984-10-04 1986-05-02 Ulvac Corp Rotary vacuum filtering and drying apparatus
DK161743C (en) * 1989-07-03 1992-02-17 Niro Atomizer As PROCEDURE AND APPARATUS FOR AGGLOMERATION OF A POWDER-SHAPED MATERIAL

Also Published As

Publication number Publication date
ES2178938A1 (en) 2003-01-01

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