ES2178938B1 - PROCEDURE FOR EMPTY PRODUCTION OF PHARMACEUTICAL PREPARATIONS OF CONTROLLED RELEASE AND / OR GASTRORRESISTENT. - Google Patents
PROCEDURE FOR EMPTY PRODUCTION OF PHARMACEUTICAL PREPARATIONS OF CONTROLLED RELEASE AND / OR GASTRORRESISTENT.Info
- Publication number
- ES2178938B1 ES2178938B1 ES200002685A ES200002685A ES2178938B1 ES 2178938 B1 ES2178938 B1 ES 2178938B1 ES 200002685 A ES200002685 A ES 200002685A ES 200002685 A ES200002685 A ES 200002685A ES 2178938 B1 ES2178938 B1 ES 2178938B1
- Authority
- ES
- Spain
- Prior art keywords
- procedure
- controlled release
- pharmaceutical preparations
- pharmaceutical
- gastrorresistent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Landscapes
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Procedimiento para la producción a vacío de preparaciones farmacéuticas de liberación controlada y/o gastrorresistentes. Comprende la obtención de "pellets" y/o granulados de un principio activo mediante secado a vacío de una mezcla de dicho principio activo con uno o más excipientes farmacéuticamente aceptables destinados a impartir gastrorresistencia, llevándose a cabo dicho secado a vacío en una cuba giratoria provista de movimiento angular en la que se hace vacío al tiempo que se inyecta aire comprimido y/o nitrógeno en proporciones reducidas. Los pellets y/o granulados obtenidos tienen un tamaño de partícula comprendido entre 200 y 1000 {mi}. El procedimiento es especialmente adecuado para principios activos tales como omeprazol, diclofenaco, aspirina e ibuprofeno. El procedimiento tiene aplicación en el sector farmacéutico, en especial farmacéutico-galénico.Procedure for the vacuum production of pharmaceutical preparations of controlled release and / or gastro-resistant. It comprises obtaining "pellets" and / or granules of an active principle by vacuum drying a mixture of said active principle with one or more pharmaceutically acceptable excipients intended to impart gastro-resistance, said vacuum drying being carried out in a rotating bowl provided angular movement in which it is empty while compressed air and / or nitrogen are injected in reduced proportions. The pellets and / or granules obtained have a particle size between 200 and 1000 {mi}. The procedure is especially suitable for active ingredients such as omeprazole, diclofenac, aspirin and ibuprofen. The procedure has application in the pharmaceutical sector, especially pharmaceutical-Galenic.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES200002685A ES2178938B1 (en) | 2000-11-07 | 2000-11-07 | PROCEDURE FOR EMPTY PRODUCTION OF PHARMACEUTICAL PREPARATIONS OF CONTROLLED RELEASE AND / OR GASTRORRESISTENT. |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES200002685A ES2178938B1 (en) | 2000-11-07 | 2000-11-07 | PROCEDURE FOR EMPTY PRODUCTION OF PHARMACEUTICAL PREPARATIONS OF CONTROLLED RELEASE AND / OR GASTRORRESISTENT. |
Publications (2)
Publication Number | Publication Date |
---|---|
ES2178938A1 ES2178938A1 (en) | 2003-01-01 |
ES2178938B1 true ES2178938B1 (en) | 2003-12-16 |
Family
ID=8495575
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES200002685A Expired - Fee Related ES2178938B1 (en) | 2000-11-07 | 2000-11-07 | PROCEDURE FOR EMPTY PRODUCTION OF PHARMACEUTICAL PREPARATIONS OF CONTROLLED RELEASE AND / OR GASTRORRESISTENT. |
Country Status (1)
Country | Link |
---|---|
ES (1) | ES2178938B1 (en) |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3511900A (en) * | 1967-08-22 | 1970-05-12 | Ciba Geigy Corp | Granulating process |
JPS6168133A (en) * | 1984-09-08 | 1986-04-08 | Shinjiro Tsuji | Granulating method |
JPS6186913A (en) * | 1984-10-04 | 1986-05-02 | Ulvac Corp | Rotary vacuum filtering and drying apparatus |
DK161743C (en) * | 1989-07-03 | 1992-02-17 | Niro Atomizer As | PROCEDURE AND APPARATUS FOR AGGLOMERATION OF A POWDER-SHAPED MATERIAL |
-
2000
- 2000-11-07 ES ES200002685A patent/ES2178938B1/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
ES2178938A1 (en) | 2003-01-01 |
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Legal Events
Date | Code | Title | Description |
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EC2A | Search report published |
Date of ref document: 20030101 Kind code of ref document: A1 |
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