ES2173168T3 - REAGENT TO TEST CREATINAQUINASE. - Google Patents

REAGENT TO TEST CREATINAQUINASE.

Info

Publication number
ES2173168T3
ES2173168T3 ES95902987T ES95902987T ES2173168T3 ES 2173168 T3 ES2173168 T3 ES 2173168T3 ES 95902987 T ES95902987 T ES 95902987T ES 95902987 T ES95902987 T ES 95902987T ES 2173168 T3 ES2173168 T3 ES 2173168T3
Authority
ES
Spain
Prior art keywords
reagent
phosphate
hexoquinase
glucoquinase
glucose
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES95902987T
Other languages
Spanish (es)
Inventor
Hiroyuki Tsubota
Reiko Shimada
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Iatron Laboratories Inc
Mitsubishi Kagaku Iatron Inc
Original Assignee
Iatron Laboratories Inc
Mitsubishi Kagaku Iatron Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Iatron Laboratories Inc, Mitsubishi Kagaku Iatron Inc filed Critical Iatron Laboratories Inc
Application granted granted Critical
Publication of ES2173168T3 publication Critical patent/ES2173168T3/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/48—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase
    • C12Q1/50—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase involving creatine phosphokinase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/54—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving glucose or galactose

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Emergency Medicine (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

UN REACTIVO PARA ANALIZAR UNA QUINASA DE CREATINA, QUE CONTIENE GLUCOQUINASA O HEXOQUINASA, DESHIDROGENASA DE GLUCOSA-6-FOSFATO, 5''-DIFOSFATO DE ADENOSINA, FOSFATO DE CREATINA, FOSFATO DE DINUCLEOTIDO DE ADENINA DE NICOTINAMIDA OXIDADO, SAL DE MAGNESIO Y GLUCOSA Y QUE SE COMPONE DE UN PRIMER REACTIVO LIQUIDO QUE TIENE UN VALOR DE PH DE 7,5 A 10 Y CONTIENE A MENOS UNA GLUCOQUINASA Y/O HEXOQUINASA, DESHIDROGENASA DE GLUCOSA-6FOSFATO, 5''-DIFOSFATO DE ADENOSINA Y FOSFATO DE CREATINA Y UN SEGUNDO REACTIVO LIQUIDO QUE TIENE UN VALOR DE PH DE 2 A 5 Y CONTIENE AL MENOS UN FOSFATO DE DINUCLEOTIDO DE ADENINA DE NICOTINAMIDA OXIDADO. ESTE REACTIVO SE PUEDE ALMACENAR EN ESTADO LIQUIDO PERMANECIENDO ESTABLE DURANTE UN LARGO PERIODO DE TIEMPO A TEMPERATURAS NORMALES O BAJAS Y TANTO EN LUGARES OSCUROS COMO LUMINOSOS. POR TANTO SE PUEDE UTILIZAR SIN QUE SEA NECESARIO DILUIRLO TRAS HABER ESTADO GUARDADO DURANTE UN LARGO PERIODO DE TIEMPO EN EL LUGAR DONDE SE REALIZAN LOS EXAMENES CLINICOS Y SE PUEDE UTILIZAR TAMBIEN CON ANALIZADORES AUTOMATICOS.A REAGENT TO ANALYZE A CREATIN KINASE, CONTAINING GLUCOQUINASE OR HEXOQUINASE, GLUCOSE-6-PHOSPHATE DEHYDROGENASE, 5 '' - ADENOSINE DIFFOSPHATE, CREATINE PHOSPHATE, DINUCINYNID NOSYNIDIDEOID NOSYNIDIDEOID NOSYNIDEOSIDEIDEIDEOSYNIDIDEOID NOSYNUCIDEIDEIDEIDEIDEIDEOSIDEIDEIDEOSIDEIDEIDEOSIDEIDEIDEOSYNIDEIDEIDEIDEIDEIDEIDEIDEIDEHYNUCIDEIDEIDEIDEIDEIDEIDEIDEIDEIDE HYDINHYDOSIDEHYDIDEIDEIDEIDEIDEIDEIDEIDEIDEIDEIDEOXYNOTHYDYYNIDEIDEIDEIDEIDEIDEIDEIDEIDEIN KINOSIDEHYDICIDEOID NOSYNUCIDEIDEIDEIDEIDEIDEIDE A GLOSSY A REAGENT FOR ANALYZING A CREATIN KINASE, CONTAINING GLUCOQUINASE OR HEXOQUINASE, DEHYDROGENASE OF GLUCOSE-6-PHOSPHATE, 5 '' THAT IS COMPOSED OF A FIRST LIQUID REAGENT THAT HAS A PH VALUE OF 7.5 TO 10 AND CONTAINS LESS THAN A GLUCOQUINASE AND / OR HEXOQUINASE, GLUCOSE-6PHOSPHATE DEHYDROGENASE, 5 '' - ADENOSINE DIFFOSPHATE AND CREATINE PHOSPHATE AND PHOSPHATE SECOND LIQUID REAGENT THAT HAS A PH VALUE OF 2 TO 5 AND CONTAINS AT LEAST AN OXIDIZED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE. THIS REAGENT CAN BE STORED IN A LIQUID STATE REMAINING STABLE DURING A LONG PERIOD OF TIME AT NORMAL OR LOW TEMPERATURES AND BOTH IN DARK AND LUMINOUS PLACES. THEREFORE, IT CAN BE USED WITHOUT NEEDING TO BE DILUTED AFTER BEING STORED DURING A LONG PERIOD OF TIME IN THE PLACE WHERE CLINICAL EXAMS ARE CARRIED OUT AND CAN ALSO BE USED WITH AUTOMATIC ANALYZERS.

ES95902987T 1993-12-20 1994-12-19 REAGENT TO TEST CREATINAQUINASE. Expired - Lifetime ES2173168T3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP34482493 1993-12-20

Publications (1)

Publication Number Publication Date
ES2173168T3 true ES2173168T3 (en) 2002-10-16

Family

ID=18372260

Family Applications (1)

Application Number Title Priority Date Filing Date
ES95902987T Expired - Lifetime ES2173168T3 (en) 1993-12-20 1994-12-19 REAGENT TO TEST CREATINAQUINASE.

Country Status (8)

Country Link
US (1) US5834227A (en)
EP (1) EP0685561B1 (en)
JP (1) JP3310296B2 (en)
KR (1) KR100319653B1 (en)
DE (1) DE69430305T2 (en)
ES (1) ES2173168T3 (en)
TW (1) TW336256B (en)
WO (1) WO1995017520A1 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5998158A (en) * 1997-05-14 1999-12-07 Fuji Photo Film Co., Ltd. Glucose free, stable dry analytical element for quantitative analysis of creatine kinase MB isozyme
JP3750955B2 (en) * 1997-04-18 2006-03-01 富士写真フイルム株式会社 Dry analytical element for quantification of creatine kinase or its MB isozyme
EP0989191B1 (en) * 1998-09-22 2002-11-27 Fuji Photo Film Co., Ltd. Dry analytical element for quantitative analysis of creatine kinase or its MB isozyme
US6799576B2 (en) * 1999-07-16 2004-10-05 Aradigm Corporation System for effecting smoking cessation
CN104374905B (en) * 2014-11-28 2016-03-30 山东博科生物产业有限公司 A kind of serum creatine kinase detection reagent

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS62104598A (en) * 1985-11-01 1987-05-15 Yatoron:Kk Reagent for measuring creatine kinase
JPH0690202B2 (en) * 1988-04-06 1994-11-14 ユニチカ株式会社 Reagent for measuring creatine kinase activity and measuring method using the same
JP3045190B2 (en) * 1991-03-14 2000-05-29 ユニチカ株式会社 Creatine kinase measurement reagent
US5587296A (en) * 1993-08-25 1996-12-24 Iatron Laboratories, Inc. Reagent for assaying glucose

Also Published As

Publication number Publication date
US5834227A (en) 1998-11-10
DE69430305T2 (en) 2002-11-21
TW336256B (en) 1998-07-11
EP0685561A4 (en) 1998-10-07
DE69430305D1 (en) 2002-05-08
EP0685561A1 (en) 1995-12-06
JP3310296B2 (en) 2002-08-05
EP0685561B1 (en) 2002-04-03
WO1995017520A1 (en) 1995-06-29
KR100319653B1 (en) 2002-06-20
KR960701217A (en) 1996-02-24

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