ES2164940T3 - BIOADHESIVE SOLID DOSAGE FORM. - Google Patents
BIOADHESIVE SOLID DOSAGE FORM.Info
- Publication number
- ES2164940T3 ES2164940T3 ES96944692T ES96944692T ES2164940T3 ES 2164940 T3 ES2164940 T3 ES 2164940T3 ES 96944692 T ES96944692 T ES 96944692T ES 96944692 T ES96944692 T ES 96944692T ES 2164940 T3 ES2164940 T3 ES 2164940T3
- Authority
- ES
- Spain
- Prior art keywords
- solid dosage
- dosage form
- dosage forms
- bioadhesive
- bioadhesive solid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000007909 solid dosage form Substances 0.000 title abstract 3
- 239000000227 bioadhesive Substances 0.000 title abstract 2
- VZCYOOQTPOCHFL-OWOJBTEDSA-L fumarate(2-) Chemical compound [O-]C(=O)\C=C\C([O-])=O VZCYOOQTPOCHFL-OWOJBTEDSA-L 0.000 abstract 1
- 239000000314 lubricant Substances 0.000 abstract 1
- 239000011159 matrix material Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 229920000642 polymer Polymers 0.000 abstract 1
- 239000008247 solid mixture Substances 0.000 abstract 1
- VZCYOOQTPOCHFL-UHFFFAOYSA-N trans-butenedioic acid Natural products OC(=O)C=CC(O)=O VZCYOOQTPOCHFL-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Abstract
LA PRESENTE INVENCION TRATA DE COMPOSICIONES FARMACEUTICAS BIOADHESIVAS QUE CONTIENEN UNA CANTIDAD FARMACEUTICAMENTE ACEPTABLE DE UN PRINCIPIO ACTIVO, DESDE UN 80 % A UN 98,8 % (P/P) DE ALMIDON PREGELATINIZADO, Y DESDE UN 1 % A UN 10 % (P/P) DE UN POLIMERO FORMADOR DE UNA MATRIZ HIDROFILA, QUE SE CARACTERIZA PORQUE LA COMPOSICION INCLUYE ADEMAS DESDE UN 0,2 % AUN 5 % (P/P) DE FUMARATO DE ALQUILO C 16-22 ALCALINO COMO LUBRICANTE; DE FORMAS DE DOSIFICACION SOLIDAS TALES COMO COMPRIMIDOS QUE RESULTAN ADECUADAS PARA LA ADMINISTRACION POR VIA ORAL, NASAL, RECTAL Y VAGINAL; DE PROCEDIMIENTOS PARA PREPARAR LAS COMPOSICIONES Y LAS FORMAS DE DOSIFICACION SOLIDAS.THIS INVENTION IS ABOUT BIOADHESIVE PHARMACEUTICAL COMPOSITIONS CONTAINING A PHARMACEUTICALLY ACCEPTABLE AMOUNT OF AN ACTIVE PRINCIPLE, FROM 80% TO 98.8% (P / P) OF PREGELATINIZED ALMIDON, AND FROM 1% TO 10% (P / P) OF A HYDROPHYLE MATRIX FORMING POLYMER, WHICH IS CHARACTERIZED BECAUSE THE COMPOSITION INCLUDES ALSO FROM 0.2% TO 5% (P / P) OF C 16-22 ALKYL FUMARATE AS LUBRICANT; OF SOLID DOSAGE FORMS SUCH AS TABLETS THAT ARE SUITABLE FOR ADMINISTRATION BY ORAL, NASAL, RECTAL AND VAGINAL ROUTES; OF PROCEDURES TO PREPARE SOLID COMPOSITIONS AND DOSAGE FORMS.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP95203649 | 1995-12-27 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2164940T3 true ES2164940T3 (en) | 2002-03-01 |
Family
ID=8221021
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES96944692T Expired - Lifetime ES2164940T3 (en) | 1995-12-27 | 1996-12-20 | BIOADHESIVE SOLID DOSAGE FORM. |
Country Status (27)
| Country | Link |
|---|---|
| US (1) | US6303147B1 (en) |
| EP (1) | EP0869772B1 (en) |
| JP (1) | JP4317264B2 (en) |
| KR (1) | KR100459029B1 (en) |
| CN (1) | CN1146401C (en) |
| AT (1) | ATE206304T1 (en) |
| AU (1) | AU713849B2 (en) |
| BR (1) | BR9612291A (en) |
| CA (1) | CA2232152C (en) |
| CY (1) | CY2269B1 (en) |
| CZ (1) | CZ298690B6 (en) |
| DE (1) | DE69615704T2 (en) |
| DK (1) | DK0869772T3 (en) |
| EA (1) | EA000818B1 (en) |
| ES (1) | ES2164940T3 (en) |
| HK (1) | HK1015680A1 (en) |
| HU (1) | HU228350B1 (en) |
| IL (1) | IL123636A (en) |
| NO (1) | NO320015B1 (en) |
| NZ (1) | NZ325844A (en) |
| PL (1) | PL186278B1 (en) |
| PT (1) | PT869772E (en) |
| SI (1) | SI0869772T1 (en) |
| SK (1) | SK283370B6 (en) |
| TR (1) | TR199800894T2 (en) |
| WO (1) | WO1997024109A1 (en) |
| ZA (1) | ZA9610886B (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8715728B2 (en) | 2004-08-13 | 2014-05-06 | Boehringer Ingelheim International Gmbh | Extended release pellet formulation containing pramipexole or a pharmaceutically acceptable salt thereof |
Families Citing this family (47)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20080213378A1 (en) * | 1998-10-01 | 2008-09-04 | Elan Pharma International, Ltd. | Nanoparticulate statin formulations and novel statin combinations |
| AU6283299A (en) * | 1998-10-01 | 2000-04-17 | Elan Pharma International Limited | Controlled release nanoparticulate compositions |
| US20040013613A1 (en) * | 2001-05-18 | 2004-01-22 | Jain Rajeev A | Rapidly disintegrating solid oral dosage form |
| US7521068B2 (en) * | 1998-11-12 | 2009-04-21 | Elan Pharma International Ltd. | Dry powder aerosols of nanoparticulate drugs |
| US6428814B1 (en) * | 1999-10-08 | 2002-08-06 | Elan Pharma International Ltd. | Bioadhesive nanoparticulate compositions having cationic surface stabilizers |
| SK288541B6 (en) | 1999-03-31 | 2018-03-05 | Janssen Pharmaceutica N. V. | Pregelatinized starch in a hydrophilic controlled release formulation |
| US7503493B2 (en) * | 1999-10-25 | 2009-03-17 | Silverbrook Research Pty Ltd | Method and system for digitizing freehand graphics with user-selected properties |
| US20040156872A1 (en) * | 2000-05-18 | 2004-08-12 | Elan Pharma International Ltd. | Novel nimesulide compositions |
| US7198795B2 (en) * | 2000-09-21 | 2007-04-03 | Elan Pharma International Ltd. | In vitro methods for evaluating the in vivo effectiveness of dosage forms of microparticulate of nanoparticulate active agent compositions |
| US8980334B2 (en) * | 2001-02-28 | 2015-03-17 | Axiomedic Ltd. | Double-layered absorbable solid compositions for the topical treatment of oral mucosal disorders |
| EP1236466B1 (en) * | 2001-02-28 | 2011-09-21 | Axiomedic Ltd. | Solid self-adhesive compositions for topical treatment of oral mucosal disorders |
| FR2827517B1 (en) * | 2001-07-23 | 2003-10-24 | Bioalliance Pharma | EXTENDED RELEASE BIOADHESIVE THERAPEUTIC SYSTEMS |
| US20030083286A1 (en) * | 2001-08-22 | 2003-05-01 | Ching-Leou Teng | Bioadhesive compositions and methods for enhanced intestinal drug absorption |
| US20030124196A1 (en) | 2001-08-22 | 2003-07-03 | Susan Weinbach | Pulsatile release compositions and methods for enhanced intestinal drug absorption |
| US7709026B2 (en) * | 2001-10-29 | 2010-05-04 | Columbia Laboratories, Inc. | Low concentration of peroxide for treating or preventing vaginal infections |
| US7846478B2 (en) * | 2002-01-31 | 2010-12-07 | Henkel Ag & Co. Kgaa | Bioadhesive composition |
| PT1471887E (en) | 2002-02-04 | 2010-07-16 | Elan Pharma Int Ltd | Nanoparticulate compositions having lysozyme as a surface stabilizer |
| WO2004006959A1 (en) * | 2002-07-16 | 2004-01-22 | Elan Pharma International, Ltd | Liquid dosage compositions of stable nanoparticulate active agents |
| PE20040134A1 (en) | 2002-07-25 | 2004-03-06 | Pharmacia Corp | PRAMIPEXOL ONCE-A-DAY DOSAGE FORM |
| GB0222522D0 (en) | 2002-09-27 | 2002-11-06 | Controlled Therapeutics Sct | Water-swellable polymers |
| WO2005032554A1 (en) | 2003-10-03 | 2005-04-14 | Astron Research Pvt. Ltd | A novel transmucosal delivery system |
| US20080234353A1 (en) * | 2004-03-24 | 2008-09-25 | Reynir Eyjolfsson | Formulations of Ramipril |
| CA2563609C (en) * | 2004-04-22 | 2012-11-06 | Duocort Ab | Pharmaceutical compositions for acute glucocorticoid therapy |
| TWI338583B (en) * | 2004-05-20 | 2011-03-11 | Otsuka Pharma Co Ltd | Solid pharmaceutical formulation |
| GB0417401D0 (en) | 2004-08-05 | 2004-09-08 | Controlled Therapeutics Sct | Stabilised prostaglandin composition |
| US20070048369A1 (en) * | 2005-08-26 | 2007-03-01 | National Starch And Chemical Investment Holding Corporation | Mucosal delivery tablet |
| GB0518129D0 (en) * | 2005-09-06 | 2005-10-12 | Arrow Int Ltd | Ramipril formulation |
| US20070098782A1 (en) * | 2005-10-28 | 2007-05-03 | Selamine Limited | Ramipril Formulation |
| GB2431579A (en) * | 2005-10-28 | 2007-05-02 | Arrow Int Ltd | Ramipril formulations |
| US8349120B2 (en) * | 2006-03-07 | 2013-01-08 | Ora Health Corporation | Multi-layer patch made on a sheet and enclosed in a blister |
| EP1837020A1 (en) | 2006-03-24 | 2007-09-26 | Bioalliance Pharma | Mucosal bioadhesive slow release carrier for delivering active principles |
| US20070248655A1 (en) * | 2006-04-21 | 2007-10-25 | Haley Jeffrey T | Lenticular shaped protective mouth sore discs |
| EP2037895A4 (en) * | 2006-05-23 | 2009-12-02 | Orahealth Corp | Xylitol troches and methods of use |
| US20070293587A1 (en) * | 2006-05-23 | 2007-12-20 | Haley Jeffrey T | Combating sinus, throat, and blood infections with xylitol delivered in the mouth |
| GB0613333D0 (en) | 2006-07-05 | 2006-08-16 | Controlled Therapeutics Sct | Hydrophilic polyurethane compositions |
| GB0613638D0 (en) | 2006-07-08 | 2006-08-16 | Controlled Therapeutics Sct | Polyurethane elastomers |
| BRPI0713203A2 (en) * | 2006-07-12 | 2012-04-03 | Controlled Therapeutics Scotland Ltda | insert, methods, packing, recoverable device and insertable device |
| GB0620685D0 (en) | 2006-10-18 | 2006-11-29 | Controlled Therapeutics Sct | Bioresorbable polymers |
| GB0624087D0 (en) * | 2006-12-01 | 2007-01-10 | Selamine Ltd | Ramipril combination salt |
| EP3620153A1 (en) | 2007-07-06 | 2020-03-11 | Lupin Limited | Pharmaceutical compositions for gastrointestinal drug delivery |
| US20120027855A1 (en) | 2007-07-06 | 2012-02-02 | Lupin Limited | Pharmaceutical compositions for gastrointestinal drug delivery |
| WO2009008006A2 (en) * | 2007-07-06 | 2009-01-15 | Lupin Limited | Pharmaceutical compositions for gastrointestinal drug delivery |
| EP2163240A1 (en) * | 2008-09-12 | 2010-03-17 | Universita' Degli Studi Di Genova | A method for the production of bioadhesive compact matrices |
| KR20140114269A (en) | 2010-12-20 | 2014-09-26 | 이 아이 듀폰 디 네모아 앤드 캄파니 | Targeted perhydrolases |
| EP2964200B1 (en) * | 2013-03-06 | 2017-04-19 | Novartis AG | Formulations of organic compounds |
| CN105193768A (en) * | 2015-08-27 | 2015-12-30 | 武汉武药科技有限公司 | Triamcinolone acetonide oral sticking tablet and preparation process thereof |
| PL3484486T3 (en) * | 2016-07-15 | 2023-12-11 | H2 Water Technologies Ltd | Composition for producing hydrogen rich water |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3554764A (en) | 1967-12-21 | 1971-01-12 | Gen Foods Corp | Freeze-thaw resistant flour and starch thickener blend |
| DE3739690A1 (en) * | 1987-11-24 | 1989-06-08 | Hoechst Ag | STABILIZED MEDICINAL PRODUCTS, METHOD FOR THEIR PRODUCTION AND STABLE MEDICAL PREPARATIONS |
| EP0451433B1 (en) * | 1990-04-12 | 1996-10-23 | Janssen Pharmaceutica N.V. | Composition of a bioadhesive sustained delivery carrier for drug administration |
| US5330761A (en) * | 1993-01-29 | 1994-07-19 | Edward Mendell Co. Inc. | Bioadhesive tablet for non-systemic use products |
| US5662933A (en) * | 1993-09-09 | 1997-09-02 | Edward Mendell Co., Inc. | Controlled release formulation (albuterol) |
| US5370878A (en) | 1993-09-30 | 1994-12-06 | Hallmark Pharmaceuticals, Inc. | Method for preparing a direct compression granulated acetaminophen composition |
| TW355683B (en) | 1994-02-17 | 1999-04-11 | Janssen Pharmaceutica Nv | Composition containing micronized nebivolol |
| ES2082723B1 (en) * | 1994-07-20 | 1996-10-01 | Lilly Sa | PHARMACEUTICAL FORMULATION OF FLUOXETINE IN A DISPERSIBLE FORM. |
| US5656283A (en) | 1995-06-08 | 1997-08-12 | Ortho Pharmaceutical Corporation | In-situ lyophilization of vaginal suppository in unit dose applicator and resultant product |
-
1996
- 1996-12-20 IL IL12363696A patent/IL123636A/en not_active IP Right Cessation
- 1996-12-20 SK SK887-98A patent/SK283370B6/en not_active IP Right Cessation
- 1996-12-20 CA CA002232152A patent/CA2232152C/en not_active Expired - Lifetime
- 1996-12-20 BR BR9612291A patent/BR9612291A/en not_active IP Right Cessation
- 1996-12-20 HU HU9802913A patent/HU228350B1/en unknown
- 1996-12-20 KR KR1019980703055A patent/KR100459029B1/en not_active IP Right Cessation
- 1996-12-20 AT AT96944692T patent/ATE206304T1/en active
- 1996-12-20 PL PL96326196A patent/PL186278B1/en unknown
- 1996-12-20 ES ES96944692T patent/ES2164940T3/en not_active Expired - Lifetime
- 1996-12-20 US US09/091,685 patent/US6303147B1/en not_active Expired - Lifetime
- 1996-12-20 DK DK96944692T patent/DK0869772T3/en active
- 1996-12-20 TR TR1998/00894T patent/TR199800894T2/en unknown
- 1996-12-20 CZ CZ0199298A patent/CZ298690B6/en not_active IP Right Cessation
- 1996-12-20 JP JP52403297A patent/JP4317264B2/en not_active Expired - Lifetime
- 1996-12-20 WO PCT/EP1996/005884 patent/WO1997024109A1/en active IP Right Grant
- 1996-12-20 PT PT96944692T patent/PT869772E/en unknown
- 1996-12-20 EA EA199800350A patent/EA000818B1/en not_active IP Right Cessation
- 1996-12-20 EP EP96944692A patent/EP0869772B1/en not_active Expired - Lifetime
- 1996-12-20 NZ NZ325844A patent/NZ325844A/en not_active IP Right Cessation
- 1996-12-20 SI SI9630387T patent/SI0869772T1/en unknown
- 1996-12-20 DE DE69615704T patent/DE69615704T2/en not_active Expired - Lifetime
- 1996-12-20 CN CNB961978783A patent/CN1146401C/en not_active Expired - Lifetime
- 1996-12-20 AU AU13085/97A patent/AU713849B2/en not_active Expired
- 1996-12-23 ZA ZA9610886A patent/ZA9610886B/en unknown
-
1998
- 1998-03-09 NO NO19981027A patent/NO320015B1/en not_active IP Right Cessation
-
1999
- 1999-02-20 HK HK99100697A patent/HK1015680A1/en not_active IP Right Cessation
-
2002
- 2002-04-25 CY CY0200020A patent/CY2269B1/en unknown
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8715728B2 (en) | 2004-08-13 | 2014-05-06 | Boehringer Ingelheim International Gmbh | Extended release pellet formulation containing pramipexole or a pharmaceutically acceptable salt thereof |
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ES2164940T3 (en) | BIOADHESIVE SOLID DOSAGE FORM. | |
| AR022008A1 (en) | A COMPOSITION OF CONTROLLED GALANTAMINE RELEASE, A PROCESS FOR THE PREPARATION OF THE SAME, AND THE USE OF SUCH COMPOSITION FOR THE PREPARATION OF A MEDICINAL PRODUCT | |
| ES2117015T3 (en) | COMPOSITIONS CONTAINING SUMATRIPTAN. | |
| AR020727A1 (en) | USE OF 3-AMINO-4-ARIL-MALEIMIDAS DERIVATIVE COMPOUNDS FOR THE PREPARATION OF MEDICINES FOR CONDITIONS ASSOCIATED WITH A NEED FOR INHIBITION OF LAGSK-3, SUCH COMPOUNDS, PROCEDURE FOR PREPARATION AND PHARMACEUTICAL COMPOSITIONS THAT UNDERSTAND THEM | |
| UY26977A1 (en) | IMIDAZOL COMPOUNDS CONDENSED WITH ARILO OR HETEROARILO AS ANTI-INFLAMMATORY AND ANALGESIC AGENTS | |
| AR012160A1 (en) | PHARMACEUTICAL COMPOSITIONS FOR ORAL ADMINISTRATION CONTAINING 0.5% TO 20% OF N-PIPERIDINE-5- (4-CHLOROPHENYL) -1- (2,4-DICHLOROPHENYL) -4-METHYLPIRAZOLE-3-CARBOXAMIDE IN MICROCRYSTALLINE FORM AND EXCIPIENTS PHARMACEUTICAL . | |
| SE9804314D0 (en) | New pharmaceutical formulation | |
| CO5390076A1 (en) | PHARMACEUTICAL COMPOSITIONS | |
| HK1076605A1 (en) | Formulations | |
| AR044775A1 (en) | ATORVASTATIN PHARMACEUTICAL COMPOSITIONS | |
| UY27700A1 (en) | OXO COMPOUNDS - AZABYCLES. | |
| AR037239A1 (en) | COMPOSITION OF VALDECOXIB INTRAORAL DISINTEGRATION, PROCESS FOR PREPARATION, TABLET OBTAINED AND THE USE OF SUCH COMPOSITION IN THE PREPARATION OF A MEDICINAL PRODUCT. | |
| ECSP034826A (en) | METHOD FOR MANUFACTURING A PHARMACEUTICAL COMPOSITION OF LOW DOSE | |
| BR0114100A (en) | Controlled release formulations for oral administration | |
| AR035946A1 (en) | PHARMACEUTICAL COMPOSITIONS TO USE IN THE TREATMENT OF DISORDERS IN WOMEN PERIMENOPAUSIC, MENOPAUSIC OR POSMENOPAUSIC, AND USES OF SUCH COMPOSITIONS FOR THE PREPARATION OF MEDICINES | |
| AR032622A1 (en) | COMPOUNDS OF 4-AMINO-AZEPAN-3-ONA, PHARMACEUTICAL COMPOSITIONS THAT INCLUDE THEM, USEFUL INTERMEDIARIES IN THE SYNTHESIS OF SUCH COMPOUNDS, PROCEDURE FOR THE SYNTHESIS OF SUCH COMPOUNDS, AND USE OF SUCH COMPOUNDS IN THE MANUFACTURE OF MEDICINES | |
| AR002972A1 (en) | PILLS THAT HAVE A PHARMACEUTICAL MATRIX THAT PROVIDE AN APPROPRIATE PROFILE OF DRUG RELEASE, COMPOSITION FOR THE PREPARATION OF SAID PILLS, PROCESS FOR PREPARING SUCH PILLS AND DOSAGE FORMS OF SUCH COMPOSITION. | |
| AR015485A1 (en) | A TRAGABLE ORAL CAPSULE CONTAINING PAROXETINE, A SOLID FORMAT ORIGINABLE DOSE DOSAGE, A PHARMACEUTICAL FORMULATION, A PARAPREPARATION PROCEDURE OF THIS FORMULATION AND THE USE OF DISSOLVED PAROXETINE IN A VEHICLE TO MANUFACTURE TWO ORIGINAL FORMULATION | |
| BR0014440A (en) | Oral controlled release formulations | |
| AR034251A1 (en) | PHARMACEUTICAL COMPOSITIONS CONTAINING OLIGOSACARIDS, THE NEW OLIGOSACARIDS, ITS PREPARATION AND ITS USE FOR THE PREPARATION OF MEDICINES | |
| GT200000102A (en) | PHARMACEUTICAL COMPLEX. | |
| UY26176A1 (en) | POLYMORPHIC FORMS OF A AZOBICICLO CITRATE (2,2,2) OCTAN-3-AMINE AND ITS PHARMACEUTICAL COMPOSITIONS. | |
| PA8579701A1 (en) | BETA-LACTAMASA INHIBITOR PROFARMACO | |
| ES2171749T3 (en) | PHARMACEUTICAL COMPOSITIONS CONTAINING INHIBITORS OF THE AGGREGATION OF PLATES. | |
| AR023344A1 (en) | 4-ARYLOXYINDOLES, A PHARMACEUTICAL COMPOSITION THAT CONTAINS THEM AND THE USE OF THE SAME FOR THE PREPARATION OF MEDICINES |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
Ref document number: 869772 Country of ref document: ES |