ES2156901T3 - Antidepresor. - Google Patents

Antidepresor.

Info

Publication number
ES2156901T3
ES2156901T3 ES94925620T ES94925620T ES2156901T3 ES 2156901 T3 ES2156901 T3 ES 2156901T3 ES 94925620 T ES94925620 T ES 94925620T ES 94925620 T ES94925620 T ES 94925620T ES 2156901 T3 ES2156901 T3 ES 2156901T3
Authority
ES
Spain
Prior art keywords
substituted
substituted lower
lower alkyl
represents hydrogen
heterocycle
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES94925620T
Other languages
English (en)
Inventor
Fumio Suzuki
Nobuaki Koike
Junichi Shimada
Shigeto Kitamura
Shunji Ichikawa
Joji Nakamura
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
KH Neochem Co Ltd
Original Assignee
Kyowa Hakko Kogyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyowa Hakko Kogyo Co Ltd filed Critical Kyowa Hakko Kogyo Co Ltd
Application granted granted Critical
Publication of ES2156901T3 publication Critical patent/ES2156901T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/53—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Fuel-Injection Apparatus (AREA)
  • Seal Device For Vehicle (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Steroid Compounds (AREA)

Abstract

SE PRESENTA UN MEDICAMENTO CONTRA LA DEPRESION QUE CONTIENE UN DERIVADO DE LA TRIAZINA REPRESENTADO POR LA FORMULA GENERAL (I) O UNA SAL FARMACOLOGICAMENTE ACEPTABLE DEL MISMO COMO INGREDIENTE ACTIVO, EN DONDE R1 REPRESENTA HIDROGENO, ALQUILO INFERIOR SUSTITUIDO O INSUSTITUIDO O ALCANOILO INFERIOR SUSTITUIDO O INSUSTITUIDO; R2 REPRESENTA HIDROGENO, O ALQUILO INFERIOR SUSTITUIDO O INSUSTITUIDO, ALQUENILO INFERIOR SUSTITUIDO O INSUSTITUIDO, CICLOALQUILO SUSTITUIDO O INSUSTITUIDO, ARILO SUSTITUIDO O INSUSTITUIDO, ARALQUILO SUSTITUIDO O INSUSTITUIDO O HETEROCICLO SUSTITUIDO O INSUSTITUIDO; R3 REPRESENTA HETEROCICLO SUSTITUIDO O INSUSTITUIDO; X REPRESENTA UN ENLACE SIMPLE; O, S, S(O), S(O)2 O NR4, EN DONDE R4 REPRESENTA HIDROGENO O UN ALQUILO INFERIOR SUSTITUIDO O INSUSTITUIDO O R2 Y NR4 SE COMBINAN ENTRE SI PARA FORMAR UN GRUPO HETEROCICLICO SATURADO NITROGENOSO SUSTITUIDO O INSUSTITUIDO DE ENTRE 4 Y 6 MIEMBROS; Y A REPRESENTA N O CR5, EN DONDE R5 REPRESENTA HIDROGENO O ALQUILO INFERIOR SUSTITUIDO O INSUSTITUIDO.
ES94925620T 1993-09-06 1994-09-02 Antidepresor. Expired - Lifetime ES2156901T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP22143193 1993-09-06

Publications (1)

Publication Number Publication Date
ES2156901T3 true ES2156901T3 (es) 2001-08-01

Family

ID=16766640

Family Applications (1)

Application Number Title Priority Date Filing Date
ES94925620T Expired - Lifetime ES2156901T3 (es) 1993-09-06 1994-09-02 Antidepresor.

Country Status (8)

Country Link
US (1) US5789407A (es)
EP (1) EP0667349B1 (es)
AT (1) ATE198890T1 (es)
AU (1) AU7546794A (es)
CA (1) CA2148502A1 (es)
DE (1) DE69426620T2 (es)
ES (1) ES2156901T3 (es)
WO (1) WO1995007282A1 (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2639299A (en) * 1998-02-24 1999-09-15 Kyowa Hakko Kogyo Co. Ltd. Remedies/preventives for parkinson's disease
AU756144B2 (en) 1998-09-22 2003-01-02 Kyowa Hakko Kogyo Co. Ltd. (1,2,4)triazolo(1,5-c)pyrimidine derivatives
US6423844B1 (en) 2001-06-06 2002-07-23 The United States Of America As Represented By The Secretary Of The Navy Process for making 1,2,4-triazolo[4,3-a][1,3,5]triazine-3,5,7-triamine
DE602004018637D1 (de) 2003-04-09 2009-02-05 Biogen Idec Inc A2a-adenosinrezeptorantagonisten
WO2004092170A2 (en) * 2003-04-09 2004-10-28 Biogen Idec Ma Inc. Triazolotriazines and pyrazolotriazines useful as a2a adenosine receptor antagon ists
US7674791B2 (en) 2003-04-09 2010-03-09 Biogen Idec Ma Inc. Triazolopyrazines and methods of making and using the same
KR102633145B1 (ko) * 2018-06-26 2024-02-05 쩌지앙 빔그린 파머슈티컬스, 엘티디 A2a 수용체 길항제로서의 트리아졸로 트리아진 유도체
CN114901665B (zh) * 2019-12-26 2025-02-18 浙江春禾医药科技有限公司 三唑并三嗪衍生物在治疗疾病中的用途
US20240217978A1 (en) * 2021-04-23 2024-07-04 Chong Kun Dang Pharmaceutical Corp. COMPOUND AS ADENOSINE A2a RECEPTOR ANTAGONIST AND PHARMACEUTICAL COMPOSITION COMPRISING SAME

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4780464A (en) * 1986-12-08 1988-10-25 Warner-Lambert Company (1,2,4)triazolo(4,3-a)quinoxaline-4-amines
GB8901423D0 (en) * 1989-01-23 1989-03-15 Fujisawa Pharmaceutical Co Pyrazolopyridine compound and processes for preparation thereof
US5356894A (en) * 1990-05-29 1994-10-18 Rodney Peter W Morpholinyl substituted [1,2,4]-triazolo[1,5-a]triazine as antagonist
GB2244487B (en) * 1990-05-29 1994-02-02 Ici Plc Azole derivatives
GB9111130D0 (en) * 1991-05-23 1991-07-17 Ici Plc Azole derivatives
IT1260444B (it) * 1992-01-24 1996-04-09 Mario Brufani Derivati della 8-(1-amminocicloalchil)1,3-dialchilxantina, procedimenbto di preparazione e loro composizioni farmaceutiche antidepressive, nootropiche e psicostimolanti

Also Published As

Publication number Publication date
CA2148502A1 (en) 1995-03-16
DE69426620T2 (de) 2001-06-21
WO1995007282A1 (en) 1995-03-16
ATE198890T1 (de) 2001-02-15
DE69426620D1 (de) 2001-03-01
EP0667349B1 (en) 2001-01-24
US5789407A (en) 1998-08-04
AU7546794A (en) 1995-03-27
EP0667349A4 (en) 1995-11-02
EP0667349A1 (en) 1995-08-16

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