ES2145061T3 - Diagnostico y terapia a base de peptidos para el tratamiento de las espondiloartropatias. - Google Patents

Diagnostico y terapia a base de peptidos para el tratamiento de las espondiloartropatias.

Info

Publication number
ES2145061T3
ES2145061T3 ES93922142T ES93922142T ES2145061T3 ES 2145061 T3 ES2145061 T3 ES 2145061T3 ES 93922142 T ES93922142 T ES 93922142T ES 93922142 T ES93922142 T ES 93922142T ES 2145061 T3 ES2145061 T3 ES 2145061T3
Authority
ES
Spain
Prior art keywords
peptides
hla
proteins
gram negative
spondyloarthropathies
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES93922142T
Other languages
English (en)
Inventor
R Hal Scofield
John B Harley
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Oklahoma Medical Research Foundation
Original Assignee
Oklahoma Medical Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Oklahoma Medical Research Foundation filed Critical Oklahoma Medical Research Foundation
Application granted granted Critical
Publication of ES2145061T3 publication Critical patent/ES2145061T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/70539—MHC-molecules, e.g. HLA-molecules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Cell Biology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

HA SIDO DETERMINADO QUE LA HLA B27 ESTA RELACIONADA CON PROTEINAS DE BACTERIA ENTERICA GRAM NEGATIVA. LAS PROTEINAS DE ORGANISMOS ENTERICOS QUE COMPARTEN SECUENCIA CON B27, TIENDEN A TENER SECUENCIAS QUE SATISFACEN LOS MOTIVOS DE LA SECUENCIA DE LA PROTEINA LOS CUALES ESTAN PENSADOS PARA PREDECIR EL ENLACE CON B27. ESTAS SECUENCIAS (ES DECIR, PEPTIDOS) SON UTILES PARA DIAGNOSTICO Y FINES TERAPEUTICOS Y PUEDEN SER USADOS PARA DISEÑAR PEPTIDOS ADICIONALES DE BACTERIA ENTERICA GRAM NEGATIVA LOS CUALES SON IMPORTANTES PARA ESPONDILOARTROPATIAS. ESTOS PEPTIDOS PUEDEN SER USADOS PARA PROTEGER ANTICUERPOS Y CELULAS T LAS CUALES SON INDICATIVAS DE ESPONDILOARTROPATIAS. LOS PEPTIDOS SOLOS O JUNTO CON MICROGLOBULINA BETA 2 O MOLECULAS HLA SOLUBLES, PUEDEN SER USADOS PARA PRODUCIR TOLERANCIA.
ES93922142T 1992-08-31 1993-08-31 Diagnostico y terapia a base de peptidos para el tratamiento de las espondiloartropatias. Expired - Lifetime ES2145061T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/944,143 US5719064A (en) 1992-08-31 1992-08-31 Peptide diagnostics and therapeutics for spondyloarthropathies

Publications (1)

Publication Number Publication Date
ES2145061T3 true ES2145061T3 (es) 2000-07-01

Family

ID=25480875

Family Applications (1)

Application Number Title Priority Date Filing Date
ES93922142T Expired - Lifetime ES2145061T3 (es) 1992-08-31 1993-08-31 Diagnostico y terapia a base de peptidos para el tratamiento de las espondiloartropatias.

Country Status (9)

Country Link
US (1) US5719064A (es)
EP (1) EP0667781B1 (es)
AT (1) ATE190491T1 (es)
AU (1) AU5124993A (es)
CA (1) CA2143322C (es)
DE (1) DE69328114T2 (es)
DK (1) DK0667781T3 (es)
ES (1) ES2145061T3 (es)
WO (1) WO1994005303A1 (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5874531A (en) * 1995-03-07 1999-02-23 President And Fellows Of Harvard College Identification of self and non-self antigens implicated autoimmune disease
AU4459797A (en) * 1996-09-18 1998-04-14 Gerhild Wildner Peptide as diagnostic and therapeutic agent for autoimmune diseases
FR2758821B1 (fr) * 1997-01-30 1999-04-16 Centre Nat Rech Scient Utilisation d'un polypeptide a titre de recepteur cellulaire des adenovirus
FR2758822B1 (fr) * 1997-01-30 1999-07-02 Centre Nat Rech Scient Utilisation d'un polypeptide a titre de recepteur cellulaire des adenovirus
GB9715177D0 (en) * 1997-07-21 1997-09-24 Neutec Pharma Plc Medicament
WO1999038978A1 (en) 1998-01-31 1999-08-05 University Of Arkansas Methods and reagents for decreasing allergic reactions
US7100685B2 (en) * 2000-10-02 2006-09-05 Enventure Global Technology Mono-diameter wellbore casing
US6908899B2 (en) * 2001-08-17 2005-06-21 U.S. Dept. Of Veterans Affairs Pro-inflammatory fibrinopeptide
US7084247B2 (en) 2004-03-11 2006-08-01 Peptimmune, Inc. Identification of self and non-self antigens implicated in autoimmune diseases

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL85746A (en) * 1988-03-15 1994-05-30 Yeda Res & Dev Preparations comprising t-lymphocyte cells treated with 8-methoxypsoralen or cell membranes separated therefrom for preventing or treating autoimmune diseases
WO1990014835A1 (en) * 1989-05-31 1990-12-13 Scripps Clinic And Research Foundation Method to treat rheumatoid arthritis

Also Published As

Publication number Publication date
WO1994005303A1 (en) 1994-03-17
US5719064A (en) 1998-02-17
ATE190491T1 (de) 2000-04-15
AU5124993A (en) 1994-03-29
DE69328114T2 (de) 2000-09-28
DK0667781T3 (da) 2000-06-05
DE69328114D1 (en) 2000-04-20
CA2143322C (en) 1998-05-26
CA2143322A1 (en) 1994-03-17
EP0667781A4 (en) 1997-07-16
EP0667781B1 (en) 2000-03-15
EP0667781A1 (en) 1995-08-23

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