ES2136085T3 - Fragmentos de hgpiib y su uso en procedimientos que permiten la determinacion in vitro de eventos tromboticos in vivo. - Google Patents

Fragmentos de hgpiib y su uso en procedimientos que permiten la determinacion in vitro de eventos tromboticos in vivo.

Info

Publication number
ES2136085T3
ES2136085T3 ES92911047T ES92911047T ES2136085T3 ES 2136085 T3 ES2136085 T3 ES 2136085T3 ES 92911047 T ES92911047 T ES 92911047T ES 92911047 T ES92911047 T ES 92911047T ES 2136085 T3 ES2136085 T3 ES 2136085T3
Authority
ES
Spain
Prior art keywords
hgpiib
fragments
procedures
allow
thrombotic events
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES92911047T
Other languages
English (en)
Inventor
Mark H Ginsberg
Andrew L Frelinger Iii
Edward F Plow
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Scripps Research Institute
Original Assignee
Scripps Research Institute
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scripps Research Institute filed Critical Scripps Research Institute
Application granted granted Critical
Publication of ES2136085T3 publication Critical patent/ES2136085T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2839—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily
    • C07K16/2848—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily against integrin beta3-subunit-containing molecules, e.g. CD41, CD51, CD61
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/975—Kit
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/807—Apparatus included in process claim, e.g. physical support structures
    • Y10S436/808—Automated or kit

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Cell Biology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)

Abstract

SE PRESENTAN SISTEMAS DE DIAGNOSTICO, METODO, POLIPEPTIDOS Y ANTICUERPOS PARA DETECTAR LA PRESENCIA DE UN FRAGMENTO DE HGPIIB CTERMINAL DEL RECEPTOR DE PLAQUETAS GPIIB-IIIA EN UNA MUESTRA DE UN FLUIDO CORPORAL.
ES92911047T 1991-04-30 1992-04-27 Fragmentos de hgpiib y su uso en procedimientos que permiten la determinacion in vitro de eventos tromboticos in vivo. Expired - Lifetime ES2136085T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US69338891A 1991-04-30 1991-04-30

Publications (1)

Publication Number Publication Date
ES2136085T3 true ES2136085T3 (es) 1999-11-16

Family

ID=24784451

Family Applications (1)

Application Number Title Priority Date Filing Date
ES92911047T Expired - Lifetime ES2136085T3 (es) 1991-04-30 1992-04-27 Fragmentos de hgpiib y su uso en procedimientos que permiten la determinacion in vitro de eventos tromboticos in vivo.

Country Status (10)

Country Link
US (5) US5763580A (es)
EP (1) EP0583352B1 (es)
AT (1) ATE184286T1 (es)
AU (1) AU7407096A (es)
CA (1) CA2102115C (es)
DE (1) DE69229948T2 (es)
DK (1) DK0583352T3 (es)
ES (1) ES2136085T3 (es)
GR (1) GR3031803T3 (es)
WO (1) WO1992019760A1 (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0583352T3 (da) * 1991-04-30 1999-12-20 Scripps Research Inst hGPIIB fragmenter og deres anvendelse i in vitro metoder til bestemmelse af in vivo thrombotiske tilstande
US6046316A (en) * 1997-12-09 2000-04-04 Wayne State University Nucleic acid encoding truncated integrins
US6623981B2 (en) * 1998-01-27 2003-09-23 Bristol-Myers Squibb Company Detection of patients at risk for developing integrin antagonist/agonist mediated disease states
CA2331244C (en) * 2000-01-21 2009-06-30 Anchor Coin, Inc. Method and apparatus for awarding and redeeming promotional points at an electronic game
US20050233390A1 (en) * 2003-04-09 2005-10-20 Allen John W Device including a proteinaceous factor, a recombinant proteinaceous factor, and a nucleotide sequence encoding the proteinaceous factor

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5114842A (en) * 1987-07-08 1992-05-19 The Scripps Research Institute Peptides and antibodies that inhibit platelet adhesion
US5196511A (en) * 1989-12-01 1993-03-23 The Scripps Research Institute Peptides and antibodies that inhibit integrin-ligand binding
US5436163A (en) * 1989-12-01 1995-07-25 The Blood Center Of Southeastern Wisconsin Polymorphism of human platelet membrane glycoprotein IIb and diagnostic applications thereof
DK0583352T3 (da) * 1991-04-30 1999-12-20 Scripps Research Inst hGPIIB fragmenter og deres anvendelse i in vitro metoder til bestemmelse af in vivo thrombotiske tilstande

Also Published As

Publication number Publication date
AU7407096A (en) 1997-01-30
US20020177173A1 (en) 2002-11-28
CA2102115C (en) 2009-04-07
DE69229948D1 (de) 1999-10-14
US20050136482A1 (en) 2005-06-23
WO1992019760A1 (en) 1992-11-12
DE69229948T2 (de) 2000-03-16
EP0583352B1 (en) 1999-09-08
EP0583352A4 (en) 1995-06-14
GR3031803T3 (en) 2000-02-29
AU1782892A (en) 1992-12-21
US5763580A (en) 1998-06-09
US7122324B2 (en) 2006-10-17
EP0583352A1 (en) 1994-02-23
DK0583352T3 (da) 1999-12-20
US6063907A (en) 2000-05-16
AU671419B2 (en) 1996-08-29
US6323324B1 (en) 2001-11-27
ATE184286T1 (de) 1999-09-15
CA2102115A1 (en) 1992-10-31
US6787320B2 (en) 2004-09-07

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