ES2129349B1 - PROCEDURE FOR PREPARING GRANISETRON. - Google Patents

PROCEDURE FOR PREPARING GRANISETRON.

Info

Publication number
ES2129349B1
ES2129349B1 ES9700270A ES9700270A ES2129349B1 ES 2129349 B1 ES2129349 B1 ES 2129349B1 ES 9700270 A ES9700270 A ES 9700270A ES 9700270 A ES9700270 A ES 9700270A ES 2129349 B1 ES2129349 B1 ES 2129349B1
Authority
ES
Spain
Prior art keywords
procedure
salt
granisetron
preparing
preparing granisetron
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
ES9700270A
Other languages
Spanish (es)
Other versions
ES2129349A1 (en
Inventor
Laurence C Powling
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Ltd
Original Assignee
SmithKline Beecham Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SmithKline Beecham Ltd filed Critical SmithKline Beecham Ltd
Publication of ES2129349A1 publication Critical patent/ES2129349A1/en
Application granted granted Critical
Publication of ES2129349B1 publication Critical patent/ES2129349B1/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Landscapes

  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Procedimiento para preparar granisetrón haciendo reacciona ácido 1-metilindazol-3-carboxílico o una sal del mismo con un compuesto de la Estructura (3) o una sal del mismo, en la que X representa un grupo de isocianato -NCO, o un grupo que es capaz de generar un grupo de isocianato al calentar, y opcionalmente formar una sal farmacéuticamente aceptable.Procedure for preparing granisetron by reacting 1-methylindazol-3-carboxylic acid or a salt thereof with a compound of Structure (3) or a salt thereof, in which X represents an isocyanate group -NCO, or a group which it is capable of generating an isocyanate group on heating, and optionally forming a pharmaceutically acceptable salt.

ES9700270A 1996-02-13 1997-02-11 PROCEDURE FOR PREPARING GRANISETRON. Expired - Fee Related ES2129349B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9602862.6A GB9602862D0 (en) 1996-02-13 1996-02-13 Novel process

Publications (2)

Publication Number Publication Date
ES2129349A1 ES2129349A1 (en) 1999-06-01
ES2129349B1 true ES2129349B1 (en) 2000-01-01

Family

ID=10788574

Family Applications (1)

Application Number Title Priority Date Filing Date
ES9700270A Expired - Fee Related ES2129349B1 (en) 1996-02-13 1997-02-11 PROCEDURE FOR PREPARING GRANISETRON.

Country Status (2)

Country Link
ES (1) ES2129349B1 (en)
GB (1) GB9602862D0 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2197001B1 (en) * 2002-03-26 2004-11-16 Laboratorios Vita, S.A. PROCEDURE FOR OBTAINING A PHARMACEUTICALLY ACTIVE COMPOUND.
DK2164848T3 (en) 2007-06-13 2016-06-06 Inke Sa Polymorphic form of granisetronbase, to processes for obtaining them as well as the formulation containing the

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0200444B1 (en) * 1985-04-27 1992-11-11 Beecham Group Plc Azabicyclononyl-indazole-carboxamide having 5-ht antagonist activity
GB8525913D0 (en) * 1985-10-21 1985-11-27 Beecham Group Plc Compounds
GB8520616D0 (en) * 1985-08-16 1985-09-25 Beecham Group Plc Compounds
GB9404055D0 (en) * 1994-03-03 1994-04-20 Smithkline Beecham Plc Novel process

Also Published As

Publication number Publication date
GB9602862D0 (en) 1996-04-10
ES2129349A1 (en) 1999-06-01

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