ES2124162A1 - Un nuevo procedimiento para preparar compuestos farmaceuticamente activos. - Google Patents
Un nuevo procedimiento para preparar compuestos farmaceuticamente activos.Info
- Publication number
- ES2124162A1 ES2124162A1 ES09600462A ES9600462A ES2124162A1 ES 2124162 A1 ES2124162 A1 ES 2124162A1 ES 09600462 A ES09600462 A ES 09600462A ES 9600462 A ES9600462 A ES 9600462A ES 2124162 A1 ES2124162 A1 ES 2124162A1
- Authority
- ES
- Spain
- Prior art keywords
- active compounds
- pharmaceutically active
- new process
- preparing pharmaceutically
- preparing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 150000001875 compounds Chemical class 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- UGFAIRIUMAVXCW-UHFFFAOYSA-N Carbon monoxide Chemical compound [O+]#[C-] UGFAIRIUMAVXCW-UHFFFAOYSA-N 0.000 abstract 1
- 239000002262 Schiff base Substances 0.000 abstract 1
- 150000004753 Schiff bases Chemical class 0.000 abstract 1
- 229910002091 carbon monoxide Inorganic materials 0.000 abstract 1
- 125000003453 indazolyl group Chemical group N1N=C(C2=C1C=CC=C2)* 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Un nuevo procedimiento para preparar compuestos farmacéuticamente activos, en particular granisetrón, que comprende hacer reaccionar indazol sustituido en la posición 3 con monóxido de carbono y endo-3-amino-9-meti1-9-azabiciclo-[3.3.1]-nonano o una de sus bases de Schiff.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES9600462A ES2124162B1 (es) | 1995-03-01 | 1996-02-28 | Un nuevo procedimiento para preparar compuestos farmaceuticamente activos. |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9504060.6A GB9504060D0 (en) | 1995-03-01 | 1995-03-01 | Novel process |
| ES9600462A ES2124162B1 (es) | 1995-03-01 | 1996-02-28 | Un nuevo procedimiento para preparar compuestos farmaceuticamente activos. |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES2124162A1 true ES2124162A1 (es) | 1999-01-16 |
| ES2124162B1 ES2124162B1 (es) | 1999-11-16 |
Family
ID=26154953
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES9600462A Expired - Fee Related ES2124162B1 (es) | 1995-03-01 | 1996-02-28 | Un nuevo procedimiento para preparar compuestos farmaceuticamente activos. |
Country Status (1)
| Country | Link |
|---|---|
| ES (1) | ES2124162B1 (es) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2008117282A1 (en) * | 2007-03-27 | 2008-10-02 | Chemagis Ltd. | Polymorph of granisetron base and production process therefor |
| WO2008151677A1 (en) | 2007-06-13 | 2008-12-18 | Inke, S.A. | Polymorphic form of granisetron base, methods for obtaining it and formulation containing it |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0200444A2 (en) * | 1985-04-27 | 1986-11-05 | Beecham Group Plc | Azabicyclononyl-indazole-carboxamide having 5-HT antagonist activity |
| EP0214772A1 (en) * | 1985-08-16 | 1987-03-18 | Beecham Group Plc | Novel compounds |
| EP0223385A2 (en) * | 1985-10-21 | 1987-05-27 | Beecham Group Plc | 8-Azabicyclo[3,2,1]octane and 9-azabicyclo[3,3,1]nonane derivatives |
| WO1991001316A1 (en) * | 1989-07-21 | 1991-02-07 | Beecham Group Plc | New 9-azabicyclo[3.3.1]nonane-derivate |
-
1996
- 1996-02-28 ES ES9600462A patent/ES2124162B1/es not_active Expired - Fee Related
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0200444A2 (en) * | 1985-04-27 | 1986-11-05 | Beecham Group Plc | Azabicyclononyl-indazole-carboxamide having 5-HT antagonist activity |
| EP0214772A1 (en) * | 1985-08-16 | 1987-03-18 | Beecham Group Plc | Novel compounds |
| EP0223385A2 (en) * | 1985-10-21 | 1987-05-27 | Beecham Group Plc | 8-Azabicyclo[3,2,1]octane and 9-azabicyclo[3,3,1]nonane derivatives |
| WO1991001316A1 (en) * | 1989-07-21 | 1991-02-07 | Beecham Group Plc | New 9-azabicyclo[3.3.1]nonane-derivate |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2008117282A1 (en) * | 2007-03-27 | 2008-10-02 | Chemagis Ltd. | Polymorph of granisetron base and production process therefor |
| WO2008151677A1 (en) | 2007-06-13 | 2008-12-18 | Inke, S.A. | Polymorphic form of granisetron base, methods for obtaining it and formulation containing it |
| EP2164848A1 (en) | 2007-06-13 | 2010-03-24 | Inke, S.A. | Polymorphic form of granisetron base, methods for obtaining it and formulation containing it |
| EP2164848B1 (en) * | 2007-06-13 | 2016-02-24 | Inke, S.A. | Polymorphic form of granisetron base, methods for obtaining it and formulation containing it |
Also Published As
| Publication number | Publication date |
|---|---|
| ES2124162B1 (es) | 1999-11-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EC2A | Search report published |
Date of ref document: 19990116 Kind code of ref document: A1 Effective date: 19990116 |
|
| FD2A | Announcement of lapse in spain |
Effective date: 20160603 |