ES2115553B1 - Metodo para detectar la presencia de polimorfismos de dna, estuche de ensayo y acidos nucleicos recombinantes correspondientes. - Google Patents
Metodo para detectar la presencia de polimorfismos de dna, estuche de ensayo y acidos nucleicos recombinantes correspondientes.Info
- Publication number
- ES2115553B1 ES2115553B1 ES09602239A ES9602239A ES2115553B1 ES 2115553 B1 ES2115553 B1 ES 2115553B1 ES 09602239 A ES09602239 A ES 09602239A ES 9602239 A ES9602239 A ES 9602239A ES 2115553 B1 ES2115553 B1 ES 2115553B1
- Authority
- ES
- Spain
- Prior art keywords
- test kit
- recombinant nucleic
- detect
- nucleic acids
- dna
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Abstract
METODO PARA DETECTAR LA PRESENCIA DE POLIMORFISMOS DE DNA, ESTUCHE DE ENSAYO Y ACIDOS NUCLEICOS RECOMBINANTES CORRESPONDIENTES. EL METODO CONSISTE EN ANALIZAR DNA GENOMICO HUMANO, DNA GENOMICO CLONADO O DNA GENOMICO AMPLIFICADO MEDIANTE EL EMPLEO DE MOLECULAS DE OLIGONUCLEOTIDOS COMO SONDAS QUE HIBRIDAN CON UNA PORCION DEL GEN DE LA APOLIPOPROTEINA E. EN OTRA VARIANTE, LA DETECCION SE REALIZA MEDIANTE LA DIGESTION DEL DNA CON UNA O VARIAS ENZIMAS DE RESTRICCION, O BIEN MEDIANTE LA UTILIZACION DE DIFERENTES TECNICAS ELECTROFORETICAS. EL ESTUCHE DE ENSAYO SE CARACTERIZA POR UNA CANTIDAD DEFINIDA DE UNA O MAS SONDAS DE OLIGONUCLEOTIDOS MARCADOS, UNA CANTIDAD DEFINIDA DE UNA O MAS ENZIMAS DE RESTRICCION Y MEDIOS NECESARIOS PARA LA AMPLIFIACION DEL DNA. EL ACIDO NUCLEICO RECOMBINANTE A UTILIZAR EN EL METODO CONTIENE CUALQUIER FRAGMENTO DEL PROMOTOR DEL GEN DE LA APOLIPOPROTEINAEQUE INCLUYE UNA SERIE DE NUCLEOTIDOS DETERMINADOS DEL MENCIONADO GEN. LA INVENCION ES APLICABLE A LA DIAGNOSIS Y TERAPIA DE LA ENFERMEDAD DE ALZHEIMER.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES09602239A ES2115553B1 (es) | 1996-10-23 | 1996-10-23 | Metodo para detectar la presencia de polimorfismos de dna, estuche de ensayo y acidos nucleicos recombinantes correspondientes. |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES09602239A ES2115553B1 (es) | 1996-10-23 | 1996-10-23 | Metodo para detectar la presencia de polimorfismos de dna, estuche de ensayo y acidos nucleicos recombinantes correspondientes. |
Publications (2)
Publication Number | Publication Date |
---|---|
ES2115553A1 ES2115553A1 (es) | 1998-06-16 |
ES2115553B1 true ES2115553B1 (es) | 1999-02-16 |
Family
ID=8296459
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES09602239A Expired - Fee Related ES2115553B1 (es) | 1996-10-23 | 1996-10-23 | Metodo para detectar la presencia de polimorfismos de dna, estuche de ensayo y acidos nucleicos recombinantes correspondientes. |
Country Status (1)
Country | Link |
---|---|
ES (1) | ES2115553B1 (es) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2142248B1 (es) * | 1997-11-20 | 2000-11-16 | Univ Madrid Autonoma | Polimorfismos en el promotor del gen humano de la apolipoproteina e, y sus usos para aplicaciones diagnosticas y terapeuticas. |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1994009155A1 (en) * | 1992-10-13 | 1994-04-28 | Duke University | Methods of detecting alzheimer's disease |
CA2111503A1 (en) * | 1993-12-15 | 1995-06-16 | Mcgill University | Apolipoprotein e polymorphism and alzheimer's disease |
GB9408465D0 (en) * | 1994-04-27 | 1994-06-22 | Univ Mcgill | Apolipoprotein e polymorphism & treatment of alzheimer's disease |
-
1996
- 1996-10-23 ES ES09602239A patent/ES2115553B1/es not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
ES2115553A1 (es) | 1998-06-16 |
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