ES2115535A1 - Process for the preparation of D-(-)-amino acid amides - Google Patents

Process for the preparation of D-(-)-amino acid amides

Info

Publication number
ES2115535A1
ES2115535A1 ES09601209A ES9601209A ES2115535A1 ES 2115535 A1 ES2115535 A1 ES 2115535A1 ES 09601209 A ES09601209 A ES 09601209A ES 9601209 A ES9601209 A ES 9601209A ES 2115535 A1 ES2115535 A1 ES 2115535A1
Authority
ES
Spain
Prior art keywords
amino acid
acid amides
preparation
amides
salt
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES09601209A
Other languages
Spanish (es)
Other versions
ES2115535B1 (en
Inventor
Sevilla Javier Adrio
Gonzalez Juan Carlos Carretero
Ruano Jose Luis Garcia
Bayo Antonio Pallares
Morales Manuel Esteban
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Deretil SA
Original Assignee
Derivados del Etilo SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Derivados del Etilo SA filed Critical Derivados del Etilo SA
Priority to ES9601209A priority Critical patent/ES2115535B1/en
Publication of ES2115535A1 publication Critical patent/ES2115535A1/en
Application granted granted Critical
Publication of ES2115535B1 publication Critical patent/ES2115535B1/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Landscapes

  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Process for the preparation of D-(-)-amino acid amides. The process for obtaining D-(-)-amino acid amides of formula (I) where R is hydrogen or a radical derived from an optionally substituted amino acid, comprises reacting a salt of an ester of a D-(-)-amino acid of formula (II) where R' is a linear or branched alkyl group containing 1 to 6 carbon atoms and X is the anion of the salt with an aqueous solution of ammonia at a temperature of between 0 and 40 degree C. Amides (I) are important intermediates for the synthesis of semisynthetic [beta]-lactam antibiotics by enzyme means.
ES9601209A 1996-05-31 1996-05-31 PROCEDURE FOR THE PREPARATION OF D - (-) - AMINO ACID AMIDES. Expired - Lifetime ES2115535B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
ES9601209A ES2115535B1 (en) 1996-05-31 1996-05-31 PROCEDURE FOR THE PREPARATION OF D - (-) - AMINO ACID AMIDES.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES9601209A ES2115535B1 (en) 1996-05-31 1996-05-31 PROCEDURE FOR THE PREPARATION OF D - (-) - AMINO ACID AMIDES.

Publications (2)

Publication Number Publication Date
ES2115535A1 true ES2115535A1 (en) 1998-06-16
ES2115535B1 ES2115535B1 (en) 1999-02-01

Family

ID=8294998

Family Applications (1)

Application Number Title Priority Date Filing Date
ES9601209A Expired - Lifetime ES2115535B1 (en) 1996-05-31 1996-05-31 PROCEDURE FOR THE PREPARATION OF D - (-) - AMINO ACID AMIDES.

Country Status (1)

Country Link
ES (1) ES2115535B1 (en)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995018112A1 (en) * 1993-12-24 1995-07-06 Oxford Asymmetry Limited Improvements in or relating to chiral auxiliaries

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995018112A1 (en) * 1993-12-24 1995-07-06 Oxford Asymmetry Limited Improvements in or relating to chiral auxiliaries

Also Published As

Publication number Publication date
ES2115535B1 (en) 1999-02-01

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