ES2111661T3 - Procedimiento para la obtencion de derivados del acido isoxazol-3,4-dicarboxilico. - Google Patents

Procedimiento para la obtencion de derivados del acido isoxazol-3,4-dicarboxilico.

Info

Publication number
ES2111661T3
ES2111661T3 ES93103978T ES93103978T ES2111661T3 ES 2111661 T3 ES2111661 T3 ES 2111661T3 ES 93103978 T ES93103978 T ES 93103978T ES 93103978 T ES93103978 T ES 93103978T ES 2111661 T3 ES2111661 T3 ES 2111661T3
Authority
ES
Spain
Prior art keywords
rest
cycloalifatic
aliphatic
hydrogen
procedure
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES93103978T
Other languages
English (en)
Inventor
Volker Dr Maywald
Thomas Dr Kuekenhoehner
Peter Dr Muenster
Stefan Dr Stahl
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BASF SE
Original Assignee
BASF SE
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by BASF SE filed Critical BASF SE
Application granted granted Critical
Publication of ES2111661T3 publication Critical patent/ES2111661T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
    • C07D261/10—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D261/18—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE DERIVADOS DEL ACIDO ISOXAZOL TUYENTES TIENEN LOS SIGNIFICADOS SIGUIENTES: R1 HIDROGENO, UN RESTO ALQUILO, CICLOALQUILO O FENILO, O UN RESTO HETEROCICLICO DE 5 A 6 ESLABONES, POR EL QUE LOS RESTOS ORGANICOS, BAJO LAS CONDICIONES DE REACCION, PUEDEN TENER SUSTITUYENTES INERTES; R2 HIDROGENO, UN RESTO ALQUILO, CICLOALQUILO, BENCILO O C3 ALQUENILO; A UN GRUPO AMINO NR3R4, EN EL QUE R3 EQUIVALE A HIDROGENO, A UN RESTO ALIFATICO O CICLOALIFATICO, Y R4 EQUIVALE A UN RESTO FENILO, ALIFATICO, CICLOALIFATICO O DADO EL CASO SUSTITUIDO, O R3 JUNTO CON R4 FORMAN UNA CADENA ALQUILENO, CON 4 A 7 ESLABONES, QUE PUEDE SER INTERRUMPIDA POR OXIGENO, AZUFRE O N LQUILO, CICLOALQUILO, BENCILO O ALQUENILO; POR MEDIO DE DESPROTONIZACION DE UN COMPUESTO CH ACIDO, DE FORMULA II POR MEDIO DE UNA BASE, Y TRANSFORMACION CON LOS CLORUROS DE ACIDO HIDROXAMICO, DE FORMULA III QUE SE CARACTERIZA PORQUE PARA LA DESPROTONIZACION SE UTILIZA UN ALCOHOLATO DE MAGNESIO, DE FORMULA IV EN LA QUER6 EQUIVALE A UN RESTO ALIFATICO O CICLOALIFATICO.
ES93103978T 1992-03-26 1993-03-11 Procedimiento para la obtencion de derivados del acido isoxazol-3,4-dicarboxilico. Expired - Lifetime ES2111661T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4209848A DE4209848A1 (de) 1992-03-26 1992-03-26 Verfahren zur Herstellung von Isoxazol-3,4-dicarbonsäurederivaten

Publications (1)

Publication Number Publication Date
ES2111661T3 true ES2111661T3 (es) 1998-03-16

Family

ID=6455082

Family Applications (1)

Application Number Title Priority Date Filing Date
ES93103978T Expired - Lifetime ES2111661T3 (es) 1992-03-26 1993-03-11 Procedimiento para la obtencion de derivados del acido isoxazol-3,4-dicarboxilico.

Country Status (4)

Country Link
US (1) US5264580A (es)
EP (1) EP0562382B1 (es)
DE (2) DE4209848A1 (es)
ES (1) ES2111661T3 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994024095A1 (en) * 1993-04-16 1994-10-27 Abbott Laboratories Immunosuppressive agents

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3502660A (en) * 1967-01-12 1970-03-24 Pfizer & Co C 2-((5'-(3' and/or 4'-substituted)isoxazoyl) methylidene)-3,4,10-trioxo-1,2,3,4,4a,9,9a,10-octahydroanthracenes
US3699117A (en) * 1969-07-29 1972-10-17 Pfizer 2-((5'-(3'-and/or 4'-substituted) isoxazolyl) aminoethyl) - 3,4,10 - trioxo-1,2,3,4,4,9,9,10-octahydroanthracenes and related compounds
EP0418667B1 (de) * 1989-09-22 1995-08-16 BASF Aktiengesellschaft Carbonsäureamide
DE3931627A1 (de) * 1989-09-22 1991-04-04 Basf Ag Carbonsaeureamide

Also Published As

Publication number Publication date
EP0562382A1 (de) 1993-09-29
DE4209848A1 (de) 1993-09-30
US5264580A (en) 1993-11-23
EP0562382B1 (de) 1998-01-21
DE59308002D1 (de) 1998-02-26

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