ES2111297T3 - Nuevos esteres de acidos carboxilicos de 2-amino-7-(1,3-dihidroxi-2-propoximetil)purina, su preparacion asi como su empleo. - Google Patents

Nuevos esteres de acidos carboxilicos de 2-amino-7-(1,3-dihidroxi-2-propoximetil)purina, su preparacion asi como su empleo.

Info

Publication number
ES2111297T3
ES2111297T3 ES94912542T ES94912542T ES2111297T3 ES 2111297 T3 ES2111297 T3 ES 2111297T3 ES 94912542 T ES94912542 T ES 94912542T ES 94912542 T ES94912542 T ES 94912542T ES 2111297 T3 ES2111297 T3 ES 2111297T3
Authority
ES
Spain
Prior art keywords
propoximetil
dihidroxi
amino
preparation
well
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES94912542T
Other languages
English (en)
Inventor
Gerhard Jahne
Matthias Helsberg
Irvin Winkler
Gerhard Gross
Thomas Scholl
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst AG
Original Assignee
Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst AG filed Critical Hoechst AG
Application granted granted Critical
Publication of ES2111297T3 publication Critical patent/ES2111297T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
    • C07D473/32—Nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

COMPUESTOS DE LA FORMULA (I), EN DONDE LOS SUSTITUYENTES R{SUP,1} Y R{SUP,2} TIENEN LOS SIGNIFICADOS CONOCIDOS. MUESTRAN UNA ACTIVIDAD ANTIVIRAL EN ALTA DISPONIBILIDAD BIOLOGICA DESPUES DE ADMINISTRACION ORAL.
ES94912542T 1993-04-09 1994-03-24 Nuevos esteres de acidos carboxilicos de 2-amino-7-(1,3-dihidroxi-2-propoximetil)purina, su preparacion asi como su empleo. Expired - Lifetime ES2111297T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4311801A DE4311801A1 (de) 1993-04-09 1993-04-09 Neue Carbonsäureester von 2-Amino-7-(1,3-dihydroxy-2-propoxymethyl)purin, deren Herstellung sowie deren Verwendung

Publications (1)

Publication Number Publication Date
ES2111297T3 true ES2111297T3 (es) 1998-03-01

Family

ID=6485206

Family Applications (1)

Application Number Title Priority Date Filing Date
ES94912542T Expired - Lifetime ES2111297T3 (es) 1993-04-09 1994-03-24 Nuevos esteres de acidos carboxilicos de 2-amino-7-(1,3-dihidroxi-2-propoximetil)purina, su preparacion asi como su empleo.

Country Status (9)

Country Link
EP (1) EP0693071B1 (es)
JP (1) JPH08508508A (es)
AT (1) ATE161011T1 (es)
AU (1) AU6505294A (es)
DE (2) DE4311801A1 (es)
DK (1) DK0693071T3 (es)
ES (1) ES2111297T3 (es)
GR (1) GR3025797T3 (es)
WO (1) WO1994024134A1 (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9800452D0 (sv) * 1998-02-13 1998-02-13 Medivir Ab Antivirals
US6458772B1 (en) 1909-10-07 2002-10-01 Medivir Ab Prodrugs
US6703394B2 (en) 1996-02-16 2004-03-09 Medivir Ab Acyclic nucleoside derivatives
US5869493A (en) * 1996-02-16 1999-02-09 Medivir Ab Acyclic nucleoside derivatives
WO1998021223A1 (en) * 1996-11-12 1998-05-22 Medivir Ab Nucleosides
ATE200900T1 (de) * 1997-08-15 2001-05-15 Medivir Ab Analoge nukleoside, wie antivirale einschliesslich inhibitoren der retroviralen reverstranskriptase und der dna polymerase des hepatitis b virus
AU1711599A (en) * 1997-12-19 1999-07-12 Bristol-Myers Squibb Company Prodrugs of lobucavir and methods of use
TWI332507B (en) 2002-11-19 2010-11-01 Hoffmann La Roche Antiviral nucleoside derivatives

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4008858A1 (de) * 1990-03-20 1991-09-26 Hoechst Ag Substituierte purine, verfahren zu ihrer hertellung sowie ihre verwendung als antivirale mittel
DE4210221A1 (de) * 1992-03-28 1993-09-30 Hoechst Ag Carbonsäureester von 2-Amino-7-(1,3-dihydroxy-2-propoxymethyl)purin, deren Herstellung sowie deren Verwendung

Also Published As

Publication number Publication date
GR3025797T3 (en) 1998-03-31
DE4311801A1 (de) 1994-10-13
DE59404784D1 (de) 1998-01-22
EP0693071A1 (de) 1996-01-24
WO1994024134A1 (de) 1994-10-27
DK0693071T3 (da) 1998-08-10
JPH08508508A (ja) 1996-09-10
EP0693071B1 (de) 1997-12-10
ATE161011T1 (de) 1997-12-15
AU6505294A (en) 1994-11-08

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