ES2111297T3 - Nuevos esteres de acidos carboxilicos de 2-amino-7-(1,3-dihidroxi-2-propoximetil)purina, su preparacion asi como su empleo. - Google Patents

Nuevos esteres de acidos carboxilicos de 2-amino-7-(1,3-dihidroxi-2-propoximetil)purina, su preparacion asi como su empleo.

Info

Publication number
ES2111297T3
ES2111297T3 ES94912542T ES94912542T ES2111297T3 ES 2111297 T3 ES2111297 T3 ES 2111297T3 ES 94912542 T ES94912542 T ES 94912542T ES 94912542 T ES94912542 T ES 94912542T ES 2111297 T3 ES2111297 T3 ES 2111297T3
Authority
ES
Spain
Prior art keywords
propoximetil
dihidroxi
amino
preparation
well
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES94912542T
Other languages
English (en)
Inventor
Gerhard Jahne
Matthias Helsberg
Irvin Winkler
Gerhard Gross
Thomas Scholl
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst AG
Original Assignee
Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst AG filed Critical Hoechst AG
Application granted granted Critical
Publication of ES2111297T3 publication Critical patent/ES2111297T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
    • C07D473/32—Nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

COMPUESTOS DE LA FORMULA (I), EN DONDE LOS SUSTITUYENTES R{SUP,1} Y R{SUP,2} TIENEN LOS SIGNIFICADOS CONOCIDOS. MUESTRAN UNA ACTIVIDAD ANTIVIRAL EN ALTA DISPONIBILIDAD BIOLOGICA DESPUES DE ADMINISTRACION ORAL.
ES94912542T 1993-04-09 1994-03-24 Nuevos esteres de acidos carboxilicos de 2-amino-7-(1,3-dihidroxi-2-propoximetil)purina, su preparacion asi como su empleo. Expired - Lifetime ES2111297T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4311801A DE4311801A1 (de) 1993-04-09 1993-04-09 Neue Carbonsäureester von 2-Amino-7-(1,3-dihydroxy-2-propoxymethyl)purin, deren Herstellung sowie deren Verwendung

Publications (1)

Publication Number Publication Date
ES2111297T3 true ES2111297T3 (es) 1998-03-01

Family

ID=6485206

Family Applications (1)

Application Number Title Priority Date Filing Date
ES94912542T Expired - Lifetime ES2111297T3 (es) 1993-04-09 1994-03-24 Nuevos esteres de acidos carboxilicos de 2-amino-7-(1,3-dihidroxi-2-propoximetil)purina, su preparacion asi como su empleo.

Country Status (9)

Country Link
EP (1) EP0693071B1 (es)
JP (1) JPH08508508A (es)
AT (1) ATE161011T1 (es)
AU (1) AU6505294A (es)
DE (2) DE4311801A1 (es)
DK (1) DK0693071T3 (es)
ES (1) ES2111297T3 (es)
GR (1) GR3025797T3 (es)
WO (1) WO1994024134A1 (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9800452D0 (sv) * 1998-02-13 1998-02-13 Medivir Ab Antivirals
US6458772B1 (en) 1909-10-07 2002-10-01 Medivir Ab Prodrugs
US6703394B2 (en) 1996-02-16 2004-03-09 Medivir Ab Acyclic nucleoside derivatives
US5869493A (en) * 1996-02-16 1999-02-09 Medivir Ab Acyclic nucleoside derivatives
EP0942916A2 (en) * 1996-11-12 1999-09-22 Medivir Aktiebolag Nucleosides
PL338643A1 (en) * 1997-08-15 2000-11-06 Medivir Ab Nucleosidic analoques such as antiviral ones comprising inhibitors of retrovirus revertase and dna polymerase of b type viral hepatic (hbv)
WO1999032490A1 (en) * 1997-12-19 1999-07-01 Bristol-Myers Squibb Company Prodrugs of lobucavir and methods of use
TWI332507B (en) 2002-11-19 2010-11-01 Hoffmann La Roche Antiviral nucleoside derivatives

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4008858A1 (de) * 1990-03-20 1991-09-26 Hoechst Ag Substituierte purine, verfahren zu ihrer hertellung sowie ihre verwendung als antivirale mittel
DE4210221A1 (de) * 1992-03-28 1993-09-30 Hoechst Ag Carbonsäureester von 2-Amino-7-(1,3-dihydroxy-2-propoxymethyl)purin, deren Herstellung sowie deren Verwendung

Also Published As

Publication number Publication date
EP0693071B1 (de) 1997-12-10
EP0693071A1 (de) 1996-01-24
DK0693071T3 (da) 1998-08-10
DE59404784D1 (de) 1998-01-22
ATE161011T1 (de) 1997-12-15
JPH08508508A (ja) 1996-09-10
DE4311801A1 (de) 1994-10-13
GR3025797T3 (en) 1998-03-31
AU6505294A (en) 1994-11-08
WO1994024134A1 (de) 1994-10-27

Similar Documents

Publication Publication Date Title
IT1256450B (it) Esteri nitrici con attivita' farmacologica e procedimento per la loro preparazione
GB9716657D0 (en) Chemical compounds
WO1999038877A3 (en) 2-(PURIN-9-yl)-TETRAHYDROFURAN-3,4-DIOL DERIVATIVES
HK1015137A1 (en) Antiviral 4-substituted-2-deoxy-2,3-didehydro derivatives of alpha d-neuraminic acid
BG103335A (en) Application of fumaric acid derivatives
AP2000001947A0 (en) Novel crystalline forms of an antiviral benzidazole compound.
ES2074846T3 (es) Nuevas naftil-etil-ureas y naftil-etil-tioureas, su procedimiento de preparacion y las composiciones farmaceuticas que las contienen.
CA2001727A1 (en) Organic Compounds
HUT61004A (en) Process for producing quinoxaline derivatives and pharmaceutical compositions comprising such compounds as active ingredient
ES2105362T3 (es) Nuevos derivados de acidos quinolon- y naftiridoncarboxilicos.
UA49884C2 (uk) ПОХІДНІ <font face="Symbol">a</font>-ГІДРОКСИКАРБОНОВОЇ КИСЛОТИ ТА ЛІКАРСЬКИЙ ЗАСІБ НА ЇХ ОСНОВІ
NZ236605A (en) 2-aminopyrimidine-4-carboxamide derivatives, preparation and pharmaceutical compositions thereof
ES2111297T3 (es) Nuevos esteres de acidos carboxilicos de 2-amino-7-(1,3-dihidroxi-2-propoximetil)purina, su preparacion asi como su empleo.
IL132599A0 (en) Substituted 3,3-diamino-2-propenenitriles their preparation and use
CA2264005A1 (en) Piperazino derivatives as neurokinin antagonists
TR200001102T2 (tr) İkameli tetrahidropirimidinen türevleri, üretimleri ve kullanımları.
CA2111083A1 (en) Novel peptides, their preparation and use
EP0331092A3 (en) Alpha-amino-carboxylic-acid derivatives, their preparation and use
EP0378824A3 (en) Use of omega-3-fatty acids as anticachexia agents
BG98644A (en) Piperazinyl (sulphonyl) amide derivatives of the camphor as oxytocin antagonists
TW252979B (es)
DE69431662T2 (de) Stabilisierte tablettenformulierung
ES2058196T3 (es) Derivados de azacromano.
ES476837A1 (es) Procedimientos de preparar derivados pirimidinicos condensa-dos con cabeza de puente de nitrogeno.
TW197946B (es)

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 693071

Country of ref document: ES