ES2109858B1 - NEW ACID DERIVATIVES (+) - (S) -2- (3-BENZOILFENIL) PROPIONICO WITH ANALGESIC ACTION AND PROCEDURE FOR ITS OBTAINING. - Google Patents

NEW ACID DERIVATIVES (+) - (S) -2- (3-BENZOILFENIL) PROPIONICO WITH ANALGESIC ACTION AND PROCEDURE FOR ITS OBTAINING.

Info

Publication number
ES2109858B1
ES2109858B1 ES9402406A ES9402406A ES2109858B1 ES 2109858 B1 ES2109858 B1 ES 2109858B1 ES 9402406 A ES9402406 A ES 9402406A ES 9402406 A ES9402406 A ES 9402406A ES 2109858 B1 ES2109858 B1 ES 2109858B1
Authority
ES
Spain
Prior art keywords
benzoilfenil
propionico
procedure
obtaining
acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
ES9402406A
Other languages
Spanish (es)
Other versions
ES2109858A1 (en
Inventor
Casellas David Mauleon
Perez M Luisa Garcia
Torro M Desamparados Fos
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Laboratorios Menarini SA
Original Assignee
Laboratorios Menarini SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratorios Menarini SA filed Critical Laboratorios Menarini SA
Priority to ES9402406A priority Critical patent/ES2109858B1/en
Priority to PCT/EP1995/004554 priority patent/WO1996016016A1/en
Priority to AU39835/95A priority patent/AU3983595A/en
Publication of ES2109858A1 publication Critical patent/ES2109858A1/en
Application granted granted Critical
Publication of ES2109858B1 publication Critical patent/ES2109858B1/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/76—Unsaturated compounds containing keto groups
    • C07C59/84—Unsaturated compounds containing keto groups containing six membered aromatic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

NUEVOS DERIVADOS DEL ACIDO (+)-(S)-2-(3-BENZOILFENIL)PROPIONICO CON ACCION ANALGESICA Y PROCEDIMIENTO PARA SU OBTENCION.LA PRESENTE INVENCION SE REFIERE A NUEVAS SALES DEL ACIDO (+)(S)-2-(3-BENZOILFENIL)PROPIONICO DE FORMULA I, FORMULA DONDE B+ ES COLINA O LA FORMA PROTONADA DE LISINA, ARGININA, ORNITINA, D-GLUCAMINA, N-METIL-D-GLUCAMINA O IMIDAZOL. EL PROCEDIMIENTO PARA SU PREPARACION COMPRENDE LA REACCION DEL ACIDO (+)-(S)-2-(3-BENZOILFENIL)PROPIONICO (II) CON LA LISINA, ARGININA, ORNITINA, HIDROXIDO DE COLINA, D-GLUCAMINA, N-METIL-DGLUCAMINA O IMIDAZOL O BIEN LA REACCION DE UNA SAL DEL ACIDO II CON LA APROPIADA SAL ORGANICA. DICHOS COMPUESTOS EXHIBEN UNA ELEVADA ACCION COMO ANALGESICOS Y ANTIINFLAMATORIOS EN TERAPIA HUMANA.NEW ACID DERIVATIVES (+) - (S) -2- (3-BENZOILFENIL) PROPIONICO WITH ANALGESIC ACTION AND PROCEDURE FOR ITS OBTAINING. THIS INVENTION REFERS TO NEW SALTS OF ACID (+) (S) -2- (3 -BENZOILFENIL) PROPIONIC OF FORMULA I, FORMULA WHERE B + IS CHOLINE OR THE PROTONATE FORM OF LYSINE, ARGININE, ORNITHINE, D-GLUCAMINE, N-METHYL-D-GLUCAMINE OR IMIDAZOLE. THE PROCEDURE FOR ITS PREPARATION INCLUDES THE REACTION OF THE ACID (+) - (S) -2- (3-BENZOILFENIL) PROPIONICO (II) WITH THE LYSINE, ARGININA, ORNITINA, COLINA HYDROXIDE, D-GLUCAMINA, N-METTIL-DGLUCAMINA Either IMIDAZOLE OR THE REACTION OF A SALT OF ACID II WITH THE PROPER ORGANIC SALT. SUCH COMPOUNDS EXHIBIT A HIGH ACTION AS ANALGESICS AND ANTI-INFLAMMATORIES IN HUMAN THERAPY.

ES9402406A 1994-11-23 1994-11-23 NEW ACID DERIVATIVES (+) - (S) -2- (3-BENZOILFENIL) PROPIONICO WITH ANALGESIC ACTION AND PROCEDURE FOR ITS OBTAINING. Expired - Fee Related ES2109858B1 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
ES9402406A ES2109858B1 (en) 1994-11-23 1994-11-23 NEW ACID DERIVATIVES (+) - (S) -2- (3-BENZOILFENIL) PROPIONICO WITH ANALGESIC ACTION AND PROCEDURE FOR ITS OBTAINING.
PCT/EP1995/004554 WO1996016016A1 (en) 1994-11-23 1995-11-20 Novel (+)-(s)-2-(3-benzoylphenyl)propionic acid derivatives with analgesic action and the process for the preparation thereof
AU39835/95A AU3983595A (en) 1994-11-23 1995-11-20 Novel (+)-(s)-2-(3-benzoylphenyl)propionic acid derivatives with analgesic action and the process for the preparation thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES9402406A ES2109858B1 (en) 1994-11-23 1994-11-23 NEW ACID DERIVATIVES (+) - (S) -2- (3-BENZOILFENIL) PROPIONICO WITH ANALGESIC ACTION AND PROCEDURE FOR ITS OBTAINING.

Publications (2)

Publication Number Publication Date
ES2109858A1 ES2109858A1 (en) 1998-01-16
ES2109858B1 true ES2109858B1 (en) 1998-08-16

Family

ID=8288066

Family Applications (1)

Application Number Title Priority Date Filing Date
ES9402406A Expired - Fee Related ES2109858B1 (en) 1994-11-23 1994-11-23 NEW ACID DERIVATIVES (+) - (S) -2- (3-BENZOILFENIL) PROPIONICO WITH ANALGESIC ACTION AND PROCEDURE FOR ITS OBTAINING.

Country Status (3)

Country Link
AU (1) AU3983595A (en)
ES (1) ES2109858B1 (en)
WO (1) WO1996016016A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2315763A (en) * 1996-07-31 1998-02-11 Procter & Gamble Preparation of an agglomerated detergent composition comprising a surfactant a an acid source
CA2293605A1 (en) 1998-04-11 1999-10-21 Paolo Luca Maria Giorgetti Pharmaceutical preparations containing hydrosoluble ketoprofen salts and their application
FR2892721B1 (en) 2005-10-28 2009-07-24 Synkem Sa NOVEL PROCESS FOR PREPARING QUATERNARY ACID AND AMMONIUM SALTS

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5179097A (en) * 1991-06-10 1993-01-12 Angres Isaac A Salts of non-steroidal anti-inflammatory carboxylic acids and anti-lipidemic carboxylic acids
WO1994020449A1 (en) * 1993-03-09 1994-09-15 Dompe'farmaceutici Spa Salts of 2-(3-benzoylphenyl)propionic acid with achiral and chiral organic bases and pharmaceutical compositions thereof

Also Published As

Publication number Publication date
ES2109858A1 (en) 1998-01-16
AU3983595A (en) 1996-06-17
WO1996016016A1 (en) 1996-05-30

Similar Documents

Publication Publication Date Title
US7888526B2 (en) Acid addition salts of 5-aminolevulinic acid or its derivatives
NO982500L (en) Process for the preparation of S (-) sodium 2- (4-isobutylphenyl) propionate with high enantiomeric purity, and the compound dihydrate thereof as such
RU95112575A (en) Arylpropionic salt, method of its preparing and pharmaceutical composition
AR063923A1 (en) SALTS OF ZOLEDRONIC ACID, PREPARATION PROCESSES AND COMPOSITIONS
BRPI0811956A8 (en) TOPICAL NON-AQUEOUS DICLOFENAC SOLUTION AND PROCESS FOR ITS PREPARATION
GT200000204A (en) DERIVATIVES OF HETEROCICLO-ALQUILSULFONIL-PIRAZOL AS ANTI-INFLAMMATORY / ANALGESIC AGENTS.
UY26256A1 (en) CARBOXYLIC ACID AMIDES, MEDICINES CONTAINING THESE COMPOUNDS, THEIR USE AND THEIR PREPARATION
NO20055127L (en) Preparation of Conjugated Linoleic Acids and Salts
IT1137640B (en) STABLE SALTS OF S-ADENOSYLMETHIONINE, PROCESS FOR THEIR PREPARATION AND THERAPEUTIC COMPOSITIONS THAT INCLUDE THEM AS AN ACTIVE PRINCIPLE
ATE476972T1 (en) USE OF VALPROIC ACID FOR THE TOPICAL TREATMENT OF MILD TO MODERATE ACNE VULGARIS
NO20062779L (en) Vaccine composition mixed with an alkylphosphatidylcholine
ES2109858B1 (en) NEW ACID DERIVATIVES (+) - (S) -2- (3-BENZOILFENIL) PROPIONICO WITH ANALGESIC ACTION AND PROCEDURE FOR ITS OBTAINING.
AR087803A1 (en) N-HYDROXI-4- {2- [3-N, N-DIMETHYLAMINOME) BENZOFURAN-2-ILCARBONYLAMINE] ETOXI} BENZAMIDE AND SCHEME TO MANAGE IT
CA2796412A1 (en) Method for treating scars with adapalene 0.3%
AR029795A1 (en) ACID DERIVATIVES 1,2,3,4-TETRAHYDROQUINOLIN-2-CARBOXILICO REPLACED, PROCEDURES FOR THEIR PREPARATION, ITS USE FOR THE PREPARATION OF MEDICINES AND MEDICINES CONTAINING THESE COMPOUNDS
AR128717A1 (en) SOLID FORMS, SALTS AND PREPARATION PROCESSES OF A CDK2 INHIBITOR
MXPA05004377A (en) Painless injectable compositions containing salt of 2-arylpropionic acids.
Torezan et al. Photodynamic therapy in dermatology: basic principles
MX9307510A (en) A PROCEDURE FOR THE PREPARATION OF ESTER DERIVATIVES OF PHENYLACETIC ACID.
ES535694A0 (en) PROCEDURE FOR THE MANUFACTURE OF BENZOIC ACID DERIVATIVES WITH ANTIMICROBIAL ACTIVITY
CA2881439C (en) Method for the treatment of acne
FR2892721B1 (en) NOVEL PROCESS FOR PREPARING QUATERNARY ACID AND AMMONIUM SALTS
AR024082A1 (en) ANTITRANSPIRANT SALTS AND METHODS FOR PREPARATION
RU2009102271A (en) Phenylacetic Acid Derivatives as Inhibitors of COX-2 (Cyclooxygenase-2)
CA1075605A (en) Infusion solutions with salts of glycerophosphates

Legal Events

Date Code Title Description
EC2A Search report published

Date of ref document: 19980116

Kind code of ref document: A1

Effective date: 19980116

FD1A Patent lapsed

Effective date: 20051124