ES2105986A1 - Use of 2- 4-(azolylbutyl)piperazinyl-(methyl) benzimidazole derivatives for preparing drugs for treating or preventing asthma - Google Patents

Use of 2- 4-(azolylbutyl)piperazinyl-(methyl) benzimidazole derivatives for preparing drugs for treating or preventing asthma

Info

Publication number
ES2105986A1
ES2105986A1 ES09502465A ES9502465A ES2105986A1 ES 2105986 A1 ES2105986 A1 ES 2105986A1 ES 09502465 A ES09502465 A ES 09502465A ES 9502465 A ES9502465 A ES 9502465A ES 2105986 A1 ES2105986 A1 ES 2105986A1
Authority
ES
Spain
Prior art keywords
azolylbutyl
piperazinyl
methyl
treating
benzimidazole derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES09502465A
Other languages
Spanish (es)
Other versions
ES2105986B1 (en
Inventor
Altisent Maria Rosa Cuberes
Constansa Jordi Frigola
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Esteve Pharmaceuticals SA
Original Assignee
Laboratorios del Dr Esteve SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratorios del Dr Esteve SA filed Critical Laboratorios del Dr Esteve SA
Publication of ES2105986A1 publication Critical patent/ES2105986A1/en
Application granted granted Critical
Publication of ES2105986B1 publication Critical patent/ES2105986B1/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

The use of 2-[4-(azolylbutyl)piperazinyl-(methyl)]benzimidazole derivatives, analogues thereof and salts thereof, for preparing drugs for treating or preventing asthma in mammals, including humans, is disclosed.
ES09502465A 1994-12-08 1995-12-07 USE OF THE DERIVATIVES OF 2- (4- (AZOLYLBUTYL) PIPERACINYL (METHYL) BENCIMIDAZOLE AND ANALAAGOS, AS WELL AS THEIR SALTS, FOR THE PREPARATION OF MEDICINES INTENDED FOR THE TREATMENT OR PROPHYLAXIS OF ASTHMA. Expired - Lifetime ES2105986B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9414766A FR2727865B1 (en) 1994-12-08 1994-12-08 USE OF 2- (4- (AZOLYBUTYL) -PIPERAZINYL- (METHYL)) - BENZIMIDAZOLE DERIVATIVES AND THEIR SALTS FOR THE PREPARATION OF MEDICINAL PRODUCTS FOR THE TREATMENT OR PROPHYLAXIS OF ASTHMA

Publications (2)

Publication Number Publication Date
ES2105986A1 true ES2105986A1 (en) 1997-10-16
ES2105986B1 ES2105986B1 (en) 1998-07-01

Family

ID=9469596

Family Applications (1)

Application Number Title Priority Date Filing Date
ES09502465A Expired - Lifetime ES2105986B1 (en) 1994-12-08 1995-12-07 USE OF THE DERIVATIVES OF 2- (4- (AZOLYLBUTYL) PIPERACINYL (METHYL) BENCIMIDAZOLE AND ANALAAGOS, AS WELL AS THEIR SALTS, FOR THE PREPARATION OF MEDICINES INTENDED FOR THE TREATMENT OR PROPHYLAXIS OF ASTHMA.

Country Status (9)

Country Link
EP (1) EP0741571A1 (en)
JP (1) JPH09508923A (en)
AU (1) AU714581B2 (en)
BR (1) BR1100852A (en)
CA (1) CA2182904A1 (en)
ES (1) ES2105986B1 (en)
FR (1) FR2727865B1 (en)
WO (1) WO1996017609A1 (en)
ZA (1) ZA9510435B (en)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0440811A1 (en) * 1989-08-28 1991-08-14 Kanebo, Ltd. Composition for percutaneous administration
EP0468884A1 (en) * 1990-07-26 1992-01-29 Laboratorios Del Dr. Esteve, S.A. Benzimidazole derivatives, their preparation and their application as medicaments
EP0507696A1 (en) * 1991-04-05 1992-10-07 Laboratorios Del Dr. Esteve, S.A. Antihistaminic and non-sedative derivatives of benzimidazol, process for their preparation and their medicinal use

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4200641A (en) * 1976-12-21 1980-04-29 Janssen Pharmaceutica, N.V. 1-[(Heterocyclyl)-alkyl]-4-diarylmethoxy piperidine derivatives
FR2668150B1 (en) * 1990-10-17 1994-11-18 Theramex NOVEL DERIVATIVES OF TERBUTYLPHENYL 1-AMINO 4-HYDROXYBUTANE, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM.

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0440811A1 (en) * 1989-08-28 1991-08-14 Kanebo, Ltd. Composition for percutaneous administration
EP0468884A1 (en) * 1990-07-26 1992-01-29 Laboratorios Del Dr. Esteve, S.A. Benzimidazole derivatives, their preparation and their application as medicaments
EP0507696A1 (en) * 1991-04-05 1992-10-07 Laboratorios Del Dr. Esteve, S.A. Antihistaminic and non-sedative derivatives of benzimidazol, process for their preparation and their medicinal use

Also Published As

Publication number Publication date
BR1100852A (en) 1999-10-13
WO1996017609A1 (en) 1996-06-13
ZA9510435B (en) 1996-06-14
EP0741571A1 (en) 1996-11-13
AU4261196A (en) 1996-06-26
JPH09508923A (en) 1997-09-09
CA2182904A1 (en) 1996-06-13
FR2727865A1 (en) 1996-06-14
FR2727865B1 (en) 1997-07-18
ES2105986B1 (en) 1998-07-01
AU714581B2 (en) 2000-01-06

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