ES2105984A1 - Recombinant adenoviruses which express antigens of the transmissible porcine gastroenteritis virus and use thereof in the formulation of vaccines - Google Patents

Recombinant adenoviruses which express antigens of the transmissible porcine gastroenteritis virus and use thereof in the formulation of vaccines

Info

Publication number
ES2105984A1
ES2105984A1 ES09502370A ES9502370A ES2105984A1 ES 2105984 A1 ES2105984 A1 ES 2105984A1 ES 09502370 A ES09502370 A ES 09502370A ES 9502370 A ES9502370 A ES 9502370A ES 2105984 A1 ES2105984 A1 ES 2105984A1
Authority
ES
Spain
Prior art keywords
gastroenteritis virus
recombinant adenoviruses
vaccines
formulation
transmissible
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES09502370A
Other languages
Spanish (es)
Other versions
ES2105984B1 (en
Inventor
Duran Juan Plana
Luis Enjuanes
Juan Maria Torres
Carlos Miguel Sanchez
Cristian Smerdou
Carles Sune
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyeth Farma SA
Original Assignee
Cyanamid Iberica SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cyanamid Iberica SA filed Critical Cyanamid Iberica SA
Priority to ES09502370A priority Critical patent/ES2105984B1/en
Priority to PCT/ES1996/000185 priority patent/WO1997020036A1/en
Priority to AU71325/96A priority patent/AU7132596A/en
Publication of ES2105984A1 publication Critical patent/ES2105984A1/en
Application granted granted Critical
Publication of ES2105984B1 publication Critical patent/ES2105984B1/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/10011—Adenoviridae
    • C12N2710/10041—Use of virus, viral particle or viral elements as a vector
    • C12N2710/10043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/20011—Coronaviridae
    • C12N2770/20022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Virology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

The recombinant adenoviruses contain in their genomes the sequence of the gene S of the transmissible porcine gastroenteritis virus or a sequence derived from said gene which contains, at least, one of the antigenic sites of the protein S of the transmissible porcine gastroenteritis virus. Said recombinant adenoviruses may be used in the formulation of vaccines in order to protect porcine cattle against the infection by the tansmissible porcine gastroenteritis virus and against the disease caused by said virus. This invention applies to the veterinary science.
ES09502370A 1995-11-30 1995-11-30 RECOMBINANT ADENOVIRUSES THAT EXPRESS TRANSMISSIBLE SWINE GASTROENTERITIS VIRUS ANTIGENS (VGPT) AND THEIR USE IN THE FORMATION OF VACCINES. Expired - Fee Related ES2105984B1 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
ES09502370A ES2105984B1 (en) 1995-11-30 1995-11-30 RECOMBINANT ADENOVIRUSES THAT EXPRESS TRANSMISSIBLE SWINE GASTROENTERITIS VIRUS ANTIGENS (VGPT) AND THEIR USE IN THE FORMATION OF VACCINES.
PCT/ES1996/000185 WO1997020036A1 (en) 1995-11-30 1996-10-01 Recombinant adenoviruses which express antigens of the transmissible porcine gastroenteritis virus and use thereof in the formulation of vaccines
AU71325/96A AU7132596A (en) 1995-11-30 1996-10-01 Recombinant adenoviruses which express antigens of the transmissible porcine gastroenteritis virus and use thereof in the formulation of vaccines

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES09502370A ES2105984B1 (en) 1995-11-30 1995-11-30 RECOMBINANT ADENOVIRUSES THAT EXPRESS TRANSMISSIBLE SWINE GASTROENTERITIS VIRUS ANTIGENS (VGPT) AND THEIR USE IN THE FORMATION OF VACCINES.

Publications (2)

Publication Number Publication Date
ES2105984A1 true ES2105984A1 (en) 1997-10-16
ES2105984B1 ES2105984B1 (en) 1998-04-16

Family

ID=8292359

Family Applications (1)

Application Number Title Priority Date Filing Date
ES09502370A Expired - Fee Related ES2105984B1 (en) 1995-11-30 1995-11-30 RECOMBINANT ADENOVIRUSES THAT EXPRESS TRANSMISSIBLE SWINE GASTROENTERITIS VIRUS ANTIGENS (VGPT) AND THEIR USE IN THE FORMATION OF VACCINES.

Country Status (3)

Country Link
AU (1) AU7132596A (en)
ES (1) ES2105984B1 (en)
WO (1) WO1997020036A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AUPO856097A0 (en) * 1997-08-14 1997-09-04 Commonwealth Scientific And Industrial Research Organisation Vector
FR2789695B1 (en) * 1999-02-11 2003-03-07 Merial Sas VIRAL VACCINES AND VACCINES BASED ON RECOMBINANT AND REPLICATIVE SWINE ADENOVIRUSES
US7569217B2 (en) 2001-09-24 2009-08-04 University Of Saskatchewan Porcine adenovirus E1 and E4 regions

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991018627A1 (en) * 1990-05-29 1991-12-12 Smithkline Beecham Corporation Swine pneumonia vaccine and method for the preparation thereof

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991018627A1 (en) * 1990-05-29 1991-12-12 Smithkline Beecham Corporation Swine pneumonia vaccine and method for the preparation thereof

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
CALLEBAUT, P. et al. "Development of a recombinant vector virus for vaccination against viral diarrhoea and respiratory disease in pigs" MEDED. FAC. LANDBOUWWET., UNIV. GENT. 1992. Vol. 57 (4b), pßginas 2077-2084 *
CARLOS M. SANCHEZ et al. "Genetic evolution and tropism of transmissible gastroenteritis coronavirus". VIROLOGY. 1992. Vol. 190, pßginas 92-105 *
CRISTIAN SMERDOU et al. "Induction of an immune response to transmissible gastroenteritis coronavirus using vectors with enteric Tropism" ADV. EXP. MED. BIOL. 1993. Vol. 342 (CORONAVIRUSES), pßginas 455-462 *
LUIS ENJUANES et al. "Antigen selection and presentation to protect against transmissible gastroenteritis coronavirus" VETERINARY MICROBIOLOGY. 1992. Vol. 33, pßginas 249-262 *
SYLVIA HU et al. "Studies of TGEV spike protein Gp 195 expressed in E. Coli and by a TGE-Vaccinia virus recombinant". ADVANCES IN EXPERIMENTAL MEDICINE AND BIOLOGY. 1985. Vol. 185, pßginas 63-82 *
TORRES, JUAN M. et al. "Induction of Antibodies Protecting against transmissible gastroenteritis coronavirus (TGEV) by recombinant adenovirus expressing TGEV Spike protein". VIROLOGY. 10 de noviembre de 1995. Vol. 213, pßginas 503-516 *

Also Published As

Publication number Publication date
ES2105984B1 (en) 1998-04-16
WO1997020036A1 (en) 1997-06-05
AU7132596A (en) 1997-06-19

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