ES2103237A1 - New compound derived from chromene - Google Patents

New compound derived from chromene

Info

Publication number
ES2103237A1
ES2103237A1 ES09600323A ES9600323A ES2103237A1 ES 2103237 A1 ES2103237 A1 ES 2103237A1 ES 09600323 A ES09600323 A ES 09600323A ES 9600323 A ES9600323 A ES 9600323A ES 2103237 A1 ES2103237 A1 ES 2103237A1
Authority
ES
Spain
Prior art keywords
chromene
new compound
compound derived
psychosis
schizophrenia
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES09600323A
Other languages
Spanish (es)
Other versions
ES2103237B1 (en
Inventor
Rafael Fouget
Lluis Anglada
Jordi Bolos
Jose A Ortiz
Aurelio Sacristan
Josep M Castello
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ferrer Internacional SA
Original Assignee
Ferrer Internacional SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ferrer Internacional SA filed Critical Ferrer Internacional SA
Priority to TW085103637A priority Critical patent/TW353071B/en
Priority to IL11764696A priority patent/IL117646A/en
Priority to MX9601163A priority patent/MX9601163A/en
Priority to PT96912012T priority patent/PT765323E/en
Priority to EP96912012A priority patent/EP0765323B1/en
Priority to US08/750,790 priority patent/US5736558A/en
Priority to DK96912012T priority patent/DK0765323T3/en
Priority to AU55004/96A priority patent/AU696494B2/en
Priority to JP53071696A priority patent/JP3916662B2/en
Priority to PCT/EP1996/001551 priority patent/WO1996032389A1/en
Priority to NZ306447A priority patent/NZ306447A/en
Priority to DE69613783T priority patent/DE69613783T2/en
Priority to KR1019960707131A priority patent/KR100396474B1/en
Priority to CA002192596A priority patent/CA2192596C/en
Priority to AT96912012T priority patent/ATE203022T1/en
Priority to NO965300A priority patent/NO307517B1/en
Publication of ES2103237A1 publication Critical patent/ES2103237A1/en
Application granted granted Critical
Publication of ES2103237B1 publication Critical patent/ES2103237B1/en
Priority to GR20010401686T priority patent/GR3036825T3/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

New compound derived from chromene New compound derived from chromene of formula I and its pharmaceutically acceptable addition salts, useful in the treatment of psychosis, schizophrenia and anxiety. This invention also describes processes for obtaining them and pharmaceutical compositions containing them.
ES9600323A 1995-04-12 1996-02-09 NEW COMPOUND DERIVED FROM CHROMENE. Expired - Fee Related ES2103237B1 (en)

Priority Applications (17)

Application Number Priority Date Filing Date Title
TW085103637A TW353071B (en) 1995-04-12 1996-03-22 Chromene compounds with neutroleptic activity, their preparation and pharmaceutical compositions
IL11764696A IL117646A (en) 1995-04-12 1996-03-25 7-¬3-¬4-(6-fluoro-1,2-benzisoxazole-3-YL)piperidin-1-YL¾propoxy¾3-alkyl-chromen-4-ones their preparation their uses and pharmaceutical compositions comprising them
MX9601163A MX9601163A (en) 1995-04-12 1996-03-28 New chromene derivative compounds.
KR1019960707131A KR100396474B1 (en) 1995-04-12 1996-04-11 4- (6-Fluoro-1,2-benzisooxazolyl) -1-piperidinyl-propoxy-chromen-4-one derivatives for the treatment of psychosis, schizophrenia and mental anxiety, preparations by derivatives thereof Chemical composition and preparation method
US08/750,790 US5736558A (en) 1995-04-12 1996-04-11 4-(6-fluoro-1,2-benzisoxazolyl)-1 piperidinyl-propoxy-chromen-4-one-one-derivatives, their preparation and their use in the treatment of psychosis, schizophrenia and anxiety
DK96912012T DK0765323T3 (en) 1995-04-12 1996-04-11 4- (6-Fluoro-1,2-benzisoxazolyl) -1-piperidinylpropoxychromen-4-undivatives, their preparation and their use in the treatment of psychosis, schizophrenia and anxiety
AU55004/96A AU696494B2 (en) 1995-04-12 1996-04-11 4-(6-fluoro-1,2-benzisoxazolyl)-1-piperidinyl-propoxy -chromen-4-one derivatives, their preparation and their use in the treatment of psychosis, schizophrenia and anxiety
JP53071696A JP3916662B2 (en) 1995-04-12 1996-04-11 4- (6-Fluoro-1,2-benzisoxazolyl) -1-piperidinyl-propoxy-chromen-4-one derivatives, their preparation and their use in the treatment of psychosis, schizophrenia and anxiety
PT96912012T PT765323E (en) 1995-04-12 1996-04-11 DERIVATIVES OF 4- (6-FLUORO-1,2-BENZISOXAZOLYL) -1-PIPERIDINYL-PROPOXYCHROMEN-4-ONA, ITS PREPARATION AND ITS USE IN TREATMENT, PSYCHOSIS, SCHIZOPHRENIA AND ANXIETY
NZ306447A NZ306447A (en) 1995-04-12 1996-04-11 4-(6-fluoro-1,2-benzisoxazolyl)-1-piperidinyl-propoxy-chromen-4-one derivatives; medicaments
DE69613783T DE69613783T2 (en) 1995-04-12 1996-04-11 4- (6-FLUOR-1,2-BENZISOXAZOLYL) -1-PIPERIDINYL-PROPOXY-CHROMEN-4-ON DERIVATIVES, THEIR PRODUCTION AND THEIR USE IN THE TREATMENT OF PSYCHOSIS, SCHIZOPHRENIA AND ANXIETY
EP96912012A EP0765323B1 (en) 1995-04-12 1996-04-11 4-(6-fluoro-1,2-benzisoxazolyl)-1-piperidinyl-propoxy-chromen-4-one derivatives, their preparation and their use in the treatment of psychosis, schizophrenia and anxiety
CA002192596A CA2192596C (en) 1995-04-12 1996-04-11 4-(6-fluoro-1,2-benzisoxazolyl)-1-piperidinyl-propoxy-chromen-4-one derivatives, their preparation and their use in the treatment of psychosis, schizophrenia and anxiety
AT96912012T ATE203022T1 (en) 1995-04-12 1996-04-11 4-(6-FLUORO-1,2-BENZISOXAZOLYL)-1-PIPERIDINYL-PROPOXY-CHROMEN-4-ONE DERIVATIVES, THEIR PREPARATION AND THEIR USE IN THE TREATMENT OF PSYCHOSES, SCHIZOPHRENIA AND ANXIETY STATES
PCT/EP1996/001551 WO1996032389A1 (en) 1995-04-12 1996-04-11 4-(6-fluoro-1,2-benzisoxazolyl)-1-piperidinyl-propoxy-chromen-4-one derivatives, their preparation and their use in the treatment of psychosis, schizophrenia and anxiety
NO965300A NO307517B1 (en) 1995-04-12 1996-12-11 4- (6-Fluoro-1,2-benzisoxazolyl) -1-piperidinyl-propoxy-chromen-4-one derivatives, pharmaceutical preparations containing such derivatives, and their use
GR20010401686T GR3036825T3 (en) 1995-04-12 2001-10-08 4-(6-fluoro-1,2-benzisoxazolyl)-1-piperidinyl-propoxy-chromen-4-one derivatives, their preparation and their use in the treatment of psychosis, schizophrenia and anxiety

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES9500737A ES2101646B1 (en) 1995-04-12 1995-04-12 NEW COMPOUND DERIVED FROM CHROMENE.

Publications (2)

Publication Number Publication Date
ES2103237A1 true ES2103237A1 (en) 1997-09-01
ES2103237B1 ES2103237B1 (en) 1998-06-16

Family

ID=8290091

Family Applications (2)

Application Number Title Priority Date Filing Date
ES9500737A Expired - Fee Related ES2101646B1 (en) 1995-04-12 1995-04-12 NEW COMPOUND DERIVED FROM CHROMENE.
ES9600323A Expired - Fee Related ES2103237B1 (en) 1995-04-12 1996-02-09 NEW COMPOUND DERIVED FROM CHROMENE.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES9500737A Expired - Fee Related ES2101646B1 (en) 1995-04-12 1995-04-12 NEW COMPOUND DERIVED FROM CHROMENE.

Country Status (4)

Country Link
KR (1) KR100396474B1 (en)
ES (2) ES2101646B1 (en)
TW (1) TW353071B (en)
ZA (1) ZA962391B (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2154176A1 (en) * 1998-09-21 2001-03-16 Ferrer Int 3-(hydroxymethyl)chromen-4-ones and process for their preparation

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0190015A1 (en) * 1985-01-30 1986-08-06 Warner-Lambert Company Novel 4H-1-benzopyran-4-ones and their sulphur containing analogs
EP0402644A1 (en) * 1989-05-19 1990-12-19 Hoechst-Roussel Pharmaceuticals Incorporated N-(aryloxyalkyl)heteroarylpiperidines and -heteroarylpiperazines,a process for their preparation and their use as medicaments
EP0428437A1 (en) * 1989-11-07 1991-05-22 Adir Et Compagnie 1,2-Benzisoxazole derivatives, process for their preparation and pharmaceutical compositions containing them
ES2074966A1 (en) * 1994-02-11 1995-09-16 Vita Invest Sa Process for obtaining 3-2-[4-(6-fluoro-benzo[d]isoxazol-3- yl)-piperidin-1-yl]-ethyl-2-methyl-6,7,8,9-tetrahydro-4H- pyrido-[1,2-a]pyrimidine-4-one

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0190015A1 (en) * 1985-01-30 1986-08-06 Warner-Lambert Company Novel 4H-1-benzopyran-4-ones and their sulphur containing analogs
EP0402644A1 (en) * 1989-05-19 1990-12-19 Hoechst-Roussel Pharmaceuticals Incorporated N-(aryloxyalkyl)heteroarylpiperidines and -heteroarylpiperazines,a process for their preparation and their use as medicaments
EP0428437A1 (en) * 1989-11-07 1991-05-22 Adir Et Compagnie 1,2-Benzisoxazole derivatives, process for their preparation and pharmaceutical compositions containing them
ES2074966A1 (en) * 1994-02-11 1995-09-16 Vita Invest Sa Process for obtaining 3-2-[4-(6-fluoro-benzo[d]isoxazol-3- yl)-piperidin-1-yl]-ethyl-2-methyl-6,7,8,9-tetrahydro-4H- pyrido-[1,2-a]pyrimidine-4-one

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
JAEN, J.C. et al.: "Dopamine autoreceptor agonists as potential antipsychotics. 2. (Amino-alkoxy)-4H-1 benzopyran-4-ones." J. Med. Chem. Vol. 34, 1991, pßginas 248-256 * Tabla I * *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2154176A1 (en) * 1998-09-21 2001-03-16 Ferrer Int 3-(hydroxymethyl)chromen-4-ones and process for their preparation

Also Published As

Publication number Publication date
KR100396474B1 (en) 2003-11-28
ZA962391B (en) 1997-03-12
TW353071B (en) 1999-02-21
ES2101646B1 (en) 1998-04-01
ES2103237B1 (en) 1998-06-16
ES2101646A1 (en) 1997-07-01

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