ES2099704T3 - Purificacion de albumina. - Google Patents

Purificacion de albumina.

Info

Publication number
ES2099704T3
ES2099704T3 ES90309629T ES90309629T ES2099704T3 ES 2099704 T3 ES2099704 T3 ES 2099704T3 ES 90309629 T ES90309629 T ES 90309629T ES 90309629 T ES90309629 T ES 90309629T ES 2099704 T3 ES2099704 T3 ES 2099704T3
Authority
ES
Spain
Prior art keywords
precipitated
solution
contaminants
containing albumin
albumin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES90309629T
Other languages
English (en)
Inventor
Chong Eun Chang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alpha Therapeutic Corp
Original Assignee
Alpha Therapeutic Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alpha Therapeutic Corp filed Critical Alpha Therapeutic Corp
Application granted granted Critical
Publication of ES2099704T3 publication Critical patent/ES2099704T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/76—Albumins
    • C07K14/765—Serum albumin, e.g. HSA
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

HAY PROVISTO EN CONCORDANCIA CON LA PRACTICA DE ESTE INVENTO, UN PROCESO PARA SEPARAR EL ALBUMIN DE UNA FRACCION DE PROTERINA IMPURA QUE CONTIENE ALBUMIN. LOS CONTAMINANTES, EN UNA SOLUCION ACUOSA DE LA FRACCION DE PROTEINA IMPURA QUE CONTIENE ALBUMIN, SON PRECIPITADOS DE LA SOLUCION A UN PH DE 4.5 A 4.7. LOS CONTAMINANTES ADICIONALES QUE PERMANECEN SOLUBLES SON ENLAZADOS A UNA RESINA DE CAMBIO DE ANION. DESPUES DE QUE LOS CONTAMINANTES SON PRECIPITADOS SON QUITADOS DE LA SOLUCION QUE CONTIENE ALBUMIN, EL PH DE LA SOLUCION ES AJUSTADO DE 4.7 A 6.1, Y LOS CONTAMINANTES ADICIONALES SON PRECIPITADOS. OTROS CONTAMINANTES SON ENTONCES ENLAZADOS A LA RESINA DE CAMBIO DE ANION, Y ESOS CONTAMINANTES PRECIPITADOS Y DE CAMBIO DE ANION SON QUITADOS DE LA SOLUCION QUE CONTIENE ALBUMIN.
ES90309629T 1989-10-05 1990-09-03 Purificacion de albumina. Expired - Lifetime ES2099704T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US41728789A 1989-10-05 1989-10-05

Publications (1)

Publication Number Publication Date
ES2099704T3 true ES2099704T3 (es) 1997-06-01

Family

ID=23653345

Family Applications (1)

Application Number Title Priority Date Filing Date
ES90309629T Expired - Lifetime ES2099704T3 (es) 1989-10-05 1990-09-03 Purificacion de albumina.

Country Status (4)

Country Link
EP (1) EP0422769B1 (es)
CA (1) CA2022165C (es)
DE (1) DE69030414T2 (es)
ES (1) ES2099704T3 (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993001207A1 (en) * 1991-07-12 1993-01-21 Gist-Brocades N.V. Process for the purification of serum albumin
US5849874A (en) * 1991-07-12 1998-12-15 Gist-Brocades, N.V. Process for the purification of serum albumin
JPH07102148B2 (ja) * 1992-05-20 1995-11-08 株式会社ミドリ十字 遺伝子操作により得られるヒト血清アルブミンの製造方法、およびそれにより得られるヒト血清アルブミン含有組成物
US5728553A (en) 1992-09-23 1998-03-17 Delta Biotechnology Limited High purity albumin and method of producing
GB9902000D0 (en) 1999-01-30 1999-03-17 Delta Biotechnology Ltd Process
WO2017062536A2 (en) * 2015-10-06 2017-04-13 Kieu Hoang A method of manfacturing prothrombin complex concentrate from fraction iii and non-prothrombin complex concentrate from fraction iv
US11739166B2 (en) 2020-07-02 2023-08-29 Davol Inc. Reactive polysaccharide-based hemostatic agent

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE405549B (sv) * 1975-10-09 1978-12-18 Pharmacia Fine Chemicals Ab Forfarande for isolering av albumin ur plasmaprodukter genom kromatografisk fraktionering
FR2548670B1 (fr) * 1983-07-07 1985-10-25 Merieux Inst Procede de preparation des principales proteines du sang hemolyse sous forme non denaturee
JP3554796B2 (ja) * 1988-10-31 2004-08-18 三菱ウェルファーマ株式会社 アルブミン製剤及びその製造方法

Also Published As

Publication number Publication date
EP0422769A1 (en) 1991-04-17
DE69030414T2 (de) 1997-07-17
EP0422769B1 (en) 1997-04-09
CA2022165C (en) 1999-11-23
CA2022165A1 (en) 1991-04-06
DE69030414D1 (de) 1997-05-15

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