ES2088742A1 - Composicion antibiotica de aplicacion otica. - Google Patents

Composicion antibiotica de aplicacion otica.

Info

Publication number
ES2088742A1
ES2088742A1 ES09401411A ES9401411A ES2088742A1 ES 2088742 A1 ES2088742 A1 ES 2088742A1 ES 09401411 A ES09401411 A ES 09401411A ES 9401411 A ES9401411 A ES 9401411A ES 2088742 A1 ES2088742 A1 ES 2088742A1
Authority
ES
Spain
Prior art keywords
hydroxybenzoate
otitis
antibiotic preparation
acid
floxacin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES09401411A
Other languages
English (en)
Other versions
ES2088742B1 (es
Inventor
Vidal Carlos Monserrat
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Laboratorios Salvat SA
Original Assignee
Laboratorios Salvat SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratorios Salvat SA filed Critical Laboratorios Salvat SA
Priority to ES9401411A priority Critical patent/ES2088742B1/es
Priority to EP19950500092 priority patent/EP0689832B1/en
Priority to DE1995618954 priority patent/DE69518954T2/de
Publication of ES2088742A1 publication Critical patent/ES2088742A1/es
Application granted granted Critical
Publication of ES2088742B1 publication Critical patent/ES2088742B1/es
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0046—Ear
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

JUNTO A LA CANTIDAD DE AGUA SUFICIENTE PARA 100 ML, COMPRENDE: 0,2-0,4 G DE CIPROFLOXACINO, 0,3-0,8 G DE ACIDO LACTICO AL 20 POR CIENTO; 0,3-0,6 G DE ACIDO CLORHIDRICO 1M, 1-4 G DE GLUCOSA; 0,04-0,08 G DE P-HIDROXIBENZOATO DE METILO; 0,02-0,04 G DE P-HIDROXIBENZOATO DE ETILO; 0,7-1,6 G DE UN DISOLVENTE SELECCIONADO ENTRE PROPILENGLICOL Y POLIETILENGLICOL; Y 1-4 G DE UN VISCOSIZANTE SELECCIONADO ENTRE POLIVINILPIRROLIDONA, HIDROXIPROPILCELULOSA, HIDROXIPROPILMETILCELULOSA, CARBOXIPOLIMETILENO Y UN POLIMERO ENTRECRUZADO DERIVADO DEL ACIDO ACRILICO. TIENE UTILIDAD PARA EL TRATAMIENTO TOPICO DE OTITIS, ESPECIALMENTE DE OTITIS MEDIA CRONICA SUPURATIVA Y DE OTITIS EXTERNA DIFUSA. CONLLEVA LAS VENTAJAS DE QUE SE PUEDE APLICAR A NIÑOS Y DE QUE NO PRESENTA EL RIESGO DE OTOTOXICIDAD, EN CASOS DE PERFORACION DEL TIMPANO, ASOCIADO A OTROS ANTIBIOTICOS USADOS POR VIA OTICA.
ES9401411A 1994-06-29 1994-06-29 Composicion antibiotica de aplicacion otica. Expired - Fee Related ES2088742B1 (es)

Priority Applications (3)

Application Number Priority Date Filing Date Title
ES9401411A ES2088742B1 (es) 1994-06-29 1994-06-29 Composicion antibiotica de aplicacion otica.
EP19950500092 EP0689832B1 (en) 1994-06-29 1995-06-28 Antibiotic preparation for aural application
DE1995618954 DE69518954T2 (de) 1994-06-29 1995-06-28 Antibiotische Zubereitung zur auralen Anwendung

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES9401411A ES2088742B1 (es) 1994-06-29 1994-06-29 Composicion antibiotica de aplicacion otica.

Publications (2)

Publication Number Publication Date
ES2088742A1 true ES2088742A1 (es) 1996-08-16
ES2088742B1 ES2088742B1 (es) 1997-03-16

Family

ID=8286730

Family Applications (1)

Application Number Title Priority Date Filing Date
ES9401411A Expired - Fee Related ES2088742B1 (es) 1994-06-29 1994-06-29 Composicion antibiotica de aplicacion otica.

Country Status (3)

Country Link
EP (1) EP0689832B1 (es)
DE (1) DE69518954T2 (es)
ES (1) ES2088742B1 (es)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2160090A1 (es) * 2000-03-16 2001-10-16 Vita Invest Sa Composiciones acuosas de ciprofloxacino, contenidas en envases monodosis y su utilizacion.

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5843930A (en) * 1995-06-06 1998-12-01 Bayer Corporation Method of treating otitis with ciprofloxacin-hydrocortisone suspension
MX9701731A (es) * 1995-06-06 1997-10-31 Bayer Ag Composiciones anti-bacterianas oticas, no-irritantes, no-sensibles y no-toxicas para el oido.
EP1049459B1 (en) * 1998-01-20 2009-04-22 Applied Analytical Industries, Inc. Oral liquid compositions
US6365180B1 (en) * 1998-01-20 2002-04-02 Glenn A. Meyer Oral liquid compositions
HN1999000174A (es) * 1998-10-30 1999-10-13 Bayer Ag Formulacion medicamentosa acuisa para administracion oral.
US20040101506A1 (en) * 2002-11-25 2004-05-27 Fust Charles A. Composition for the prevention and treatment of inflammation of the ear
CA2622001A1 (en) * 2005-09-26 2007-04-05 Piedmont Pharmaceuticals Llc Methods for treatment and prevention of otitis media using chemical penetration enhancers to facilitate transmembrane drug delivery into the middle ear

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0067666A1 (en) * 1981-06-11 1982-12-22 Warner-Lambert Company Salts of antimicrobial naphthyridine and quinoline compounds and their production
EP0138018A2 (de) * 1983-09-17 1985-04-24 Bayer Ag Lösungen milchsaurer Salze von Piperazinylchinolon- und Piperazinyl-azachinoloncarbonsäuren

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3142854A1 (de) 1981-10-29 1983-05-11 Bayer Ag, 5090 Leverkusen 1-cyclopropyl-6-fluor-1,4-dihydro-4-oxo-7-piperazino-chinolin-3-carbonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel
DE3537761A1 (de) * 1985-10-24 1987-04-30 Bayer Ag Infusionsloesungen der 1-cyclopropyl-6-fluor-1,4-dihydro-4-oxo-7- (1-piperazinyl)-chinolin-3-carbonsaeure
DE3632222A1 (de) * 1986-09-23 1988-04-07 Bayer Ag Topisch anwendbare zubereitungen von gyrase-inhibitoren
US4865846A (en) 1988-06-03 1989-09-12 Kaufman Herbert E Drug delivery system
WO1990001933A1 (en) * 1988-08-26 1990-03-08 Alcon Laboratories, Inc. Combination of quinolone antibiotics and steroids for topical ophthalmic use

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0067666A1 (en) * 1981-06-11 1982-12-22 Warner-Lambert Company Salts of antimicrobial naphthyridine and quinoline compounds and their production
EP0138018A2 (de) * 1983-09-17 1985-04-24 Bayer Ag Lösungen milchsaurer Salze von Piperazinylchinolon- und Piperazinyl-azachinoloncarbonsäuren

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2160090A1 (es) * 2000-03-16 2001-10-16 Vita Invest Sa Composiciones acuosas de ciprofloxacino, contenidas en envases monodosis y su utilizacion.

Also Published As

Publication number Publication date
EP0689832A2 (en) 1996-01-03
EP0689832B1 (en) 2000-09-27
DE69518954T2 (de) 2001-04-26
DE69518954D1 (de) 2000-11-02
EP0689832A3 (en) 1998-03-11
ES2088742B1 (es) 1997-03-16

Similar Documents

Publication Publication Date Title
USD427309S (en) Pediatric catheter connector
ES8706711A1 (es) Procedimiento para la fabricacion de nuevos derivados gan- gliosidos
ES2088742A1 (es) Composicion antibiotica de aplicacion otica.
MY120501A (en) Micro-encapsulated lactobacilli for medical applications
CA2274074A1 (en) Novel compounds with analgesic effect
AU6855890A (en) Therapy with l-lactate and/or pyruvate anions related application
EP0142426A3 (en) Ophthalmic formulation containing norfloxacin and related antibiotics
CA2129651A1 (en) Polymer blends for torque transmitting catheters
CO4600679A1 (es) Derivados de antibioticos de glucopeptidos
AU4780397A (en) Nitrate esters of corticoid compounds and pharmaceutical applications thereof
AU3530997A (en) Use of complex lipids as stabilising additives to pharmaceutical preparations of digestive enzyme mixtures
AU588958B2 (en) Opthlamic use of quinoline and naphthyridine antibiotics
WO1997005870A3 (en) Use of griseofulvin for inhibiting the growth of cancers
SE8202439L (sv) 4'-jodderivat av antracyklinglykosider
EP0315113A3 (en) Inner esters of gangliosides with analgesic-antiinflammatory activity
AU1976183A (en) N-(2-amino-3,5-dibromobenzyl)- trans-4-amino-cyclohexanol derivatives
AU2313297A (en) Transdermally administered dextromethorphan as antitussive agent
EP0329008A3 (de) Cephalosporinderivative und Verfahren zu ihrer Herstellung
AU4703500A (en) Intravenous valproate for acute treatment of migraine headache
BE902796A (fr) Ester d'acetyl carnitine, sa preparation et son utilisation.
CA2203463A1 (fr) Nouveaux acides et esters de la diosmetine, et les compositions pharmaceutiques les contenant
AU2139388A (en) Glycosaminoglycane for the treatment of diabetic microangiopathy
CA2023114A1 (en) Microorganism for selective production of a specific component of avermectin and a method for selective production thereof
CA2331414A1 (en) Transdermal therapeutic system for the administration of candesartan
HUT44035A (en) Process for producing new antibiotic bbm-1675 c and d of antitumor effect and pharmaceutical preparations containing these

Legal Events

Date Code Title Description
EC2A Search report published

Date of ref document: 19960816

Kind code of ref document: A1

Effective date: 19960816

FD2A Announcement of lapse in spain

Effective date: 20141120