ES2086168T3 - Soluciones estabilizadas de alquilfosfocolina en gliceroalquileteres. - Google Patents

Soluciones estabilizadas de alquilfosfocolina en gliceroalquileteres.

Info

Publication number
ES2086168T3
ES2086168T3 ES93114672T ES93114672T ES2086168T3 ES 2086168 T3 ES2086168 T3 ES 2086168T3 ES 93114672 T ES93114672 T ES 93114672T ES 93114672 T ES93114672 T ES 93114672T ES 2086168 T3 ES2086168 T3 ES 2086168T3
Authority
ES
Spain
Prior art keywords
alkylphosphocoline
alkylers
glycal
stabilized solutions
solutions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES93114672T
Other languages
English (en)
Inventor
Jurgen Prof Dr Engel
Elisabeth Dr Wolf-Heuss
Helmut Dr Orth
Burkhard Dr Wichert
Diester Sauerbier
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Asta Medica GmbH
Original Assignee
Asta Medica GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Asta Medica GmbH filed Critical Asta Medica GmbH
Application granted granted Critical
Publication of ES2086168T3 publication Critical patent/ES2086168T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
    • A61K31/685—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Engineering & Computer Science (AREA)
  • Inorganic Chemistry (AREA)
  • Dermatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Emulsifying, Dispersing, Foam-Producing Or Wetting Agents (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Luminescent Compositions (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

LAS SOLUCIONES DE ALQUILFOSFOCOLINAS EN ETERES ALQUILGLICERINAS SE PUEDEN ELABORAR A TRAVES DEL AJUSTE DEL VALOR DE PH SOBRE UNA ZONA ENTRE PH 4 Y PH 6 ESTABLE AL ALMACENAMIENTO Y SIN AGENTES DE CONSERVACION Y AGENTES DE PROTECCION DE OXIDACION.
ES93114672T 1992-10-23 1993-09-13 Soluciones estabilizadas de alquilfosfocolina en gliceroalquileteres. Expired - Lifetime ES2086168T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4235911A DE4235911A1 (de) 1992-10-23 1992-10-23 Stabilisierte Hexadecylphosphocholinlösungen in Glycerinalkylethern

Publications (1)

Publication Number Publication Date
ES2086168T3 true ES2086168T3 (es) 1996-06-16

Family

ID=6471239

Family Applications (1)

Application Number Title Priority Date Filing Date
ES93114672T Expired - Lifetime ES2086168T3 (es) 1992-10-23 1993-09-13 Soluciones estabilizadas de alquilfosfocolina en gliceroalquileteres.

Country Status (14)

Country Link
US (1) US5446033A (es)
EP (1) EP0593897B1 (es)
JP (1) JPH06227987A (es)
CN (1) CN1052878C (es)
AT (1) ATE136784T1 (es)
CA (1) CA2109053C (es)
DE (2) DE4235911A1 (es)
DK (1) DK0593897T3 (es)
EG (1) EG20234A (es)
ES (1) ES2086168T3 (es)
GR (1) GR3020045T3 (es)
RU (1) RU2114624C1 (es)
SG (1) SG48779A1 (es)
UA (1) UA27099C2 (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6828415B2 (en) * 1993-02-19 2004-12-07 Zentaris Gmbh Oligopeptide lyophilisate, their preparation and use
FR2729050A1 (fr) * 1995-02-23 1996-07-12 Oreal Compositions resistant a la degradation microbienne
US6278004B1 (en) 1996-11-06 2001-08-21 Aventis Pharma Deutschland Gmbh Stabilized phospholipidic composition
DE10028638A1 (de) 2000-06-09 2001-12-20 Schuelke & Mayr Gmbh Lagerstabile Zusammensetzungen von Glycerinmonoalkylethern
US7041302B2 (en) 2001-01-09 2006-05-09 Biother Corporation Therapeutic modulation of the tumor inflammatory response
DE10313272A1 (de) * 2003-03-24 2004-10-21 Baxter Healthcare S.A. Verwendung von Miltefosine zur Behandlung von aktinischer oder multiplen aktinischer Keratosen
EA021785B1 (ru) * 2009-07-09 2015-08-31 Пауль Менг Жидкая фармацевтическая форма алкилфосфохолина и способ её приготовления

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5008294A (en) * 1985-02-11 1991-04-16 Chemex Pharmaceuticals, Inc. Methods of treating tumors with compositions of catecholic butanes
DE3343530A1 (de) * 1983-12-01 1985-06-13 Max Planck Gesellschaft Arzneimittel mit verbesserter penetration der gewebsmembran
IE59777B1 (en) * 1985-12-04 1994-04-06 Max Planck Gesellschaft Medicaments
EP0419998A3 (en) * 1989-09-27 1991-10-23 Asta Pharma Aktiengesellschaft Use of alkylphosphonic acid derivatives for the treatment of psoriasis

Also Published As

Publication number Publication date
EP0593897A1 (de) 1994-04-27
CA2109053A1 (en) 1994-04-24
CN1052878C (zh) 2000-05-31
DK0593897T3 (da) 1996-05-13
DE59302251D1 (de) 1996-05-23
EP0593897B1 (de) 1996-04-17
DE4235911A1 (de) 1994-04-28
RU2114624C1 (ru) 1998-07-10
CN1090174A (zh) 1994-08-03
JPH06227987A (ja) 1994-08-16
GR3020045T3 (en) 1996-08-31
ATE136784T1 (de) 1996-05-15
US5446033A (en) 1995-08-29
EG20234A (en) 1998-05-31
CA2109053C (en) 2004-02-10
UA27099C2 (uk) 2000-02-28
SG48779A1 (en) 1998-05-18

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