ES2080657A1 - Proteasas modificadas. - Google Patents
Proteasas modificadas.Info
- Publication number
- ES2080657A1 ES2080657A1 ES09302039A ES9302039A ES2080657A1 ES 2080657 A1 ES2080657 A1 ES 2080657A1 ES 09302039 A ES09302039 A ES 09302039A ES 9302039 A ES9302039 A ES 9302039A ES 2080657 A1 ES2080657 A1 ES 2080657A1
- Authority
- ES
- Spain
- Prior art keywords
- modified
- serin
- proteases
- modified proteases
- fibrinolitic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Abstract
SERIN PROTEASAS DE LA SUPERFAMILIA QUIMOTRIPSINA MODIFICADOS DE MANERA QUE MUESTRAN RESISTENCIA A LOS INHIBIDORES DE SERIN PROTEASAS. SI TALES SERIN PROTEASAS MODIFICADAS TIENE PROPIEDADES FIBRINOLITICAS, TROMBOLITICAS, ANTITROMBOTICAS O PROTROMBOTICAS, SON UTILES EN EL TRATAMIENTO DE ENFERMEDADES O TRASTORNOS DE LA COAGULACION DE LA SANGRE.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES9302039A ES2080657B1 (es) | 1993-09-27 | 1993-09-27 | Proteasas modificadas. |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES9302039A ES2080657B1 (es) | 1993-09-27 | 1993-09-27 | Proteasas modificadas. |
Publications (2)
Publication Number | Publication Date |
---|---|
ES2080657A1 true ES2080657A1 (es) | 1996-02-01 |
ES2080657B1 ES2080657B1 (es) | 1996-11-01 |
Family
ID=8283159
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES9302039A Expired - Fee Related ES2080657B1 (es) | 1993-09-27 | 1993-09-27 | Proteasas modificadas. |
Country Status (1)
Country | Link |
---|---|
ES (1) | ES2080657B1 (es) |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0381331A2 (en) * | 1989-01-17 | 1990-08-08 | Genzyme Corporation | Gene sequences encoding modified residues situated in the protease domain of tpa |
WO1990010649A1 (en) * | 1989-03-06 | 1990-09-20 | The Board Of Regents Of The University Of Texas System | Serpin resistant chymotrypsin superfamily proteases, particularly pai-1 resistant +-pa, complementary inhibitor mutants; compositions; genes; expression |
WO1991009118A2 (en) * | 1989-12-07 | 1991-06-27 | British Bio-Technology Limited | Activatable fibrinolytic and anti-thrombotic proteins |
WO1992006203A1 (en) * | 1990-09-28 | 1992-04-16 | The Board Of Regents Of The University Of Texas System | MUTANTS OF tPA WHICH ARE RESISTANT TO THEIR COGNATE SERPIN INHIBITOR |
-
1993
- 1993-09-27 ES ES9302039A patent/ES2080657B1/es not_active Expired - Fee Related
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0381331A2 (en) * | 1989-01-17 | 1990-08-08 | Genzyme Corporation | Gene sequences encoding modified residues situated in the protease domain of tpa |
WO1990010649A1 (en) * | 1989-03-06 | 1990-09-20 | The Board Of Regents Of The University Of Texas System | Serpin resistant chymotrypsin superfamily proteases, particularly pai-1 resistant +-pa, complementary inhibitor mutants; compositions; genes; expression |
WO1991009118A2 (en) * | 1989-12-07 | 1991-06-27 | British Bio-Technology Limited | Activatable fibrinolytic and anti-thrombotic proteins |
WO1992006203A1 (en) * | 1990-09-28 | 1992-04-16 | The Board Of Regents Of The University Of Texas System | MUTANTS OF tPA WHICH ARE RESISTANT TO THEIR COGNATE SERPIN INHIBITOR |
Also Published As
Publication number | Publication date |
---|---|
ES2080657B1 (es) | 1996-11-01 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
EC2A | Search report published |
Date of ref document: 19930927 Kind code of ref document: B1 Effective date: 19930927 |
|
PC2A | Transfer of patent |
Owner name: BRITISH BIOTECH PHARMACEUTICALS LIMITED |
|
FD2A | Announcement of lapse in spain |
Effective date: 20180806 |