ES2075803B1 - NEUMOLISIN DETECTION PROCEDURE - Google Patents

NEUMOLISIN DETECTION PROCEDURE

Info

Publication number
ES2075803B1
ES2075803B1 ES9302615A ES9302615A ES2075803B1 ES 2075803 B1 ES2075803 B1 ES 2075803B1 ES 9302615 A ES9302615 A ES 9302615A ES 9302615 A ES9302615 A ES 9302615A ES 2075803 B1 ES2075803 B1 ES 2075803B1
Authority
ES
Spain
Prior art keywords
detection
detection procedure
neumolysin
monotional
pneumolysin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
ES9302615A
Other languages
Spanish (es)
Other versions
ES2075803A1 (en
Inventor
Garcia Fco Javier Mendez
Los Toyos Gonzalez Juan Ram De
Valdes Fernando Vazquez
Aparicio Jesus Fernandez
Gutierrez Ana Fleites
Rumeu Carlos Hardisson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Universidad de Oviedo
Original Assignee
Universidad de Oviedo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Universidad de Oviedo filed Critical Universidad de Oviedo
Priority to ES9302615A priority Critical patent/ES2075803B1/en
Priority to EP95903822A priority patent/EP0687688A1/en
Priority to PCT/ES1994/000135 priority patent/WO1995016711A1/en
Publication of ES2075803A1 publication Critical patent/ES2075803A1/en
Application granted granted Critical
Publication of ES2075803B1 publication Critical patent/ES2075803B1/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Landscapes

  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

PROCEDIMIENTO DE DETECCION DE NEUMOLISINA. LA DETECCION SE LLEVA A CABO MEDIANTE UN INMUNOENSAYO (TIPO SANDWICH ELISA DIRECTO) EN EL QUE SE EMPLEAN PAREJAS DE ANTICUERPOS MONOCIONALES ESPECIFICOS PARA DISTINTOS EPITOPOS DE LA NEUMOLISINA. UNO DE ELLOS SE EMPLEA COMO ANTICUERPO CAPTURA Y EL OTRO COMO ANTICUERPO DE REVELADO. LA CAPTURA DE NEUMOLISINA EN MUESTRA BIOLOGICAS DE PACIENTES EN DIAGNOSTICA DE LA PRESENCIA DE NEUMOCOCOS COMO AGENTES RESPONSABLES DE LA PATOLOGIA OBSERVADA. SE REIVINDICA COMO DE NUEVA Y PROPIA INVENCION: LA DETECCION DE NEUMOLISINA EN MUESTRAS BIOLOGICAS Y LA APLICABILIDAD DE ANTICUERPOS MONOCIONALES ESPECIFICOS PARA LA NEUMOLISINA EN PROCEDIMIENTOS DE DIAGNOSTICO DE INFECCION NEUMOCOCICAS.NEUMOLYSIN DETECTION PROCEDURE. THE DETECTION IS CARRIED OUT THROUGH AN IMMUNO ASSAY (SANDWICH DIRECT ELISA TYPE) IN WHICH COUPLES OF MONOTIONAL ANTIBODIES SPECIFIC FOR DIFFERENT EPITOPES OF NEUMOLYSIN ARE USED. ONE OF THEM IS USED AS AN ANTIBODY CAPTURE AND THE OTHER AS AN ANTIBODY OF DEVELOPMENT. THE CAPTURE OF PNEUMOLYSIN IN BIOLOGICAL SAMPLES OF PATIENTS IN DIAGNOSIS OF THE PRESENCE OF PNEUMOCOCCAL AS AGENTS RESPONSIBLE FOR THE OBSERVED PATHOLOGY. CLAIMED AS A NEW AND OWN INVENTION: THE DETECTION OF PNEUMOLYSIN IN BIOLOGICAL SAMPLES AND THE APPLICABILITY OF SPECIFIC MONOTIONAL ANTIBODIES FOR PNEUMOLYSINE IN DIAGNOSTIC PROCEDURES OF PNEUMOCOCCAL INFECTION.

ES9302615A 1993-12-17 1993-12-17 NEUMOLISIN DETECTION PROCEDURE Expired - Fee Related ES2075803B1 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
ES9302615A ES2075803B1 (en) 1993-12-17 1993-12-17 NEUMOLISIN DETECTION PROCEDURE
EP95903822A EP0687688A1 (en) 1993-12-17 1994-12-17 Antibodies against pneumolysine and their applications
PCT/ES1994/000135 WO1995016711A1 (en) 1993-12-17 1994-12-17 Antibodies against pneumolysine and their applications

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES9302615A ES2075803B1 (en) 1993-12-17 1993-12-17 NEUMOLISIN DETECTION PROCEDURE

Publications (2)

Publication Number Publication Date
ES2075803A1 ES2075803A1 (en) 1995-10-01
ES2075803B1 true ES2075803B1 (en) 1996-05-16

Family

ID=8283938

Family Applications (1)

Application Number Title Priority Date Filing Date
ES9302615A Expired - Fee Related ES2075803B1 (en) 1993-12-17 1993-12-17 NEUMOLISIN DETECTION PROCEDURE

Country Status (1)

Country Link
ES (1) ES2075803B1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2022199527A1 (en) * 2021-03-22 2022-09-29 星济生物(苏州)有限公司 Antigen-binding protein targeting streptococcus pneumoniae hemolysin protein and use thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2674866A1 (en) * 1991-04-08 1992-10-09 Chemunex ANTI-ACE ANTIBODIES AND THEIR APPLICATIONS TO SPECIFIC DETECTION AND POSSIBLELY TO THE ENTRIES OF ENTEROBACTERIES ENTIRELY BY AN IMMUNOCHEMICAL METHOD.

Also Published As

Publication number Publication date
ES2075803A1 (en) 1995-10-01

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Legal Events

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FD2A Announcement of lapse in spain

Effective date: 20141120