ES2059263A1 - Procedure for obtaining (+-)-9-amino-1,2,3,4- tetrahydroacridin-1-ol - Google Patents
Procedure for obtaining (+-)-9-amino-1,2,3,4- tetrahydroacridin-1-olInfo
- Publication number
- ES2059263A1 ES2059263A1 ES09202148A ES9202148A ES2059263A1 ES 2059263 A1 ES2059263 A1 ES 2059263A1 ES 09202148 A ES09202148 A ES 09202148A ES 9202148 A ES9202148 A ES 9202148A ES 2059263 A1 ES2059263 A1 ES 2059263A1
- Authority
- ES
- Spain
- Prior art keywords
- tetrahydroacridin
- amino
- procedure
- obtaining
- formula
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Procedure for obtaining (+-)-9-amino-1,2,3,4- tetrahydroacridin-1-ol. Procedure for obtaining (+-)-9-amino-1,2,3,4- tetrahydroacridin-1-ol (of formula I). It involves cyclizing the compound of formula IV in a suitable solvent medium, with acid catalysis, and isolating the desired product by the conventional methods. The product obtained has interesting therapeutic properties as a memory-enhancing agent in Alzheimer's disease. <IMAGE>
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES9202148A ES2059263B1 (en) | 1992-10-27 | 1992-10-27 | PROCEDURE FOR OBTAINING THE (+) - 9-AMINO-1,2,3,4-TETRAHIDROACRIDIN-1-OL. |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES9202148A ES2059263B1 (en) | 1992-10-27 | 1992-10-27 | PROCEDURE FOR OBTAINING THE (+) - 9-AMINO-1,2,3,4-TETRAHIDROACRIDIN-1-OL. |
Publications (2)
Publication Number | Publication Date |
---|---|
ES2059263A1 true ES2059263A1 (en) | 1994-11-01 |
ES2059263B1 ES2059263B1 (en) | 1995-10-01 |
Family
ID=8278572
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES9202148A Expired - Fee Related ES2059263B1 (en) | 1992-10-27 | 1992-10-27 | PROCEDURE FOR OBTAINING THE (+) - 9-AMINO-1,2,3,4-TETRAHIDROACRIDIN-1-OL. |
Country Status (1)
Country | Link |
---|---|
ES (1) | ES2059263B1 (en) |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES8701165A1 (en) * | 1984-10-25 | 1986-11-16 | Hoechst Roussel Pharma | 9-Amino-1,2,3,4-tetrahydroacridin-1-ol and related compounds, a process for their preparation and their use as medicaments. |
EP0311303A2 (en) * | 1987-10-05 | 1989-04-12 | Pfizer Inc. | 4-aminopyridine derivatives |
EP0449172A1 (en) * | 1990-03-29 | 1991-10-02 | Hoechst-Roussel Pharmaceuticals Incorporated | A method of reducing a carbonyl containing acridine |
EP0499231A1 (en) * | 1991-02-13 | 1992-08-19 | Hoechst-Roussel Pharmaceuticals Incorporated | 9-Aminotetrahydroacridines and related compounds, a process for their preparation and their use as medicaments |
-
1992
- 1992-10-27 ES ES9202148A patent/ES2059263B1/en not_active Expired - Fee Related
Patent Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES8701165A1 (en) * | 1984-10-25 | 1986-11-16 | Hoechst Roussel Pharma | 9-Amino-1,2,3,4-tetrahydroacridin-1-ol and related compounds, a process for their preparation and their use as medicaments. |
ES8801213A1 (en) * | 1984-10-25 | 1988-01-01 | Hoechst Roussel Pharma | 9-Amino-1,2,3,4-tetrahydroacridin-1-ol and related compounds, a process for their preparation and their use as medicaments. |
ES8802383A1 (en) * | 1984-10-25 | 1988-05-16 | Hoechst Roussel Pharma | 9-Amino-1,2,3,4-tetrahydroacridin-1-ol and related compounds, a process for their preparation and their use as medicaments. |
EP0311303A2 (en) * | 1987-10-05 | 1989-04-12 | Pfizer Inc. | 4-aminopyridine derivatives |
EP0449172A1 (en) * | 1990-03-29 | 1991-10-02 | Hoechst-Roussel Pharmaceuticals Incorporated | A method of reducing a carbonyl containing acridine |
EP0499231A1 (en) * | 1991-02-13 | 1992-08-19 | Hoechst-Roussel Pharmaceuticals Incorporated | 9-Aminotetrahydroacridines and related compounds, a process for their preparation and their use as medicaments |
Also Published As
Publication number | Publication date |
---|---|
ES2059263B1 (en) | 1995-10-01 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD1A | Patent lapsed |
Effective date: 20001102 |