ES2059263A1 - Procedure for obtaining (+-)-9-amino-1,2,3,4- tetrahydroacridin-1-ol - Google Patents

Procedure for obtaining (+-)-9-amino-1,2,3,4- tetrahydroacridin-1-ol

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Publication number
ES2059263A1
ES2059263A1 ES09202148A ES9202148A ES2059263A1 ES 2059263 A1 ES2059263 A1 ES 2059263A1 ES 09202148 A ES09202148 A ES 09202148A ES 9202148 A ES9202148 A ES 9202148A ES 2059263 A1 ES2059263 A1 ES 2059263A1
Authority
ES
Spain
Prior art keywords
tetrahydroacridin
amino
procedure
obtaining
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES09202148A
Other languages
Spanish (es)
Other versions
ES2059263B1 (en
Inventor
Clotet Joan Huguet
Ges Jose Maria Caldero
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Vita Invest SA
Original Assignee
Vita Invest SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vita Invest SA filed Critical Vita Invest SA
Priority to ES9202148A priority Critical patent/ES2059263B1/en
Publication of ES2059263A1 publication Critical patent/ES2059263A1/en
Application granted granted Critical
Publication of ES2059263B1 publication Critical patent/ES2059263B1/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Procedure for obtaining (+-)-9-amino-1,2,3,4- tetrahydroacridin-1-ol. Procedure for obtaining (+-)-9-amino-1,2,3,4- tetrahydroacridin-1-ol (of formula I). It involves cyclizing the compound of formula IV in a suitable solvent medium, with acid catalysis, and isolating the desired product by the conventional methods. The product obtained has interesting therapeutic properties as a memory-enhancing agent in Alzheimer's disease. <IMAGE>
ES9202148A 1992-10-27 1992-10-27 PROCEDURE FOR OBTAINING THE (+) - 9-AMINO-1,2,3,4-TETRAHIDROACRIDIN-1-OL. Expired - Fee Related ES2059263B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
ES9202148A ES2059263B1 (en) 1992-10-27 1992-10-27 PROCEDURE FOR OBTAINING THE (+) - 9-AMINO-1,2,3,4-TETRAHIDROACRIDIN-1-OL.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES9202148A ES2059263B1 (en) 1992-10-27 1992-10-27 PROCEDURE FOR OBTAINING THE (+) - 9-AMINO-1,2,3,4-TETRAHIDROACRIDIN-1-OL.

Publications (2)

Publication Number Publication Date
ES2059263A1 true ES2059263A1 (en) 1994-11-01
ES2059263B1 ES2059263B1 (en) 1995-10-01

Family

ID=8278572

Family Applications (1)

Application Number Title Priority Date Filing Date
ES9202148A Expired - Fee Related ES2059263B1 (en) 1992-10-27 1992-10-27 PROCEDURE FOR OBTAINING THE (+) - 9-AMINO-1,2,3,4-TETRAHIDROACRIDIN-1-OL.

Country Status (1)

Country Link
ES (1) ES2059263B1 (en)

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES8701165A1 (en) * 1984-10-25 1986-11-16 Hoechst Roussel Pharma 9-Amino-1,2,3,4-tetrahydroacridin-1-ol and related compounds, a process for their preparation and their use as medicaments.
EP0311303A2 (en) * 1987-10-05 1989-04-12 Pfizer Inc. 4-aminopyridine derivatives
EP0449172A1 (en) * 1990-03-29 1991-10-02 Hoechst-Roussel Pharmaceuticals Incorporated A method of reducing a carbonyl containing acridine
EP0499231A1 (en) * 1991-02-13 1992-08-19 Hoechst-Roussel Pharmaceuticals Incorporated 9-Aminotetrahydroacridines and related compounds, a process for their preparation and their use as medicaments

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES8701165A1 (en) * 1984-10-25 1986-11-16 Hoechst Roussel Pharma 9-Amino-1,2,3,4-tetrahydroacridin-1-ol and related compounds, a process for their preparation and their use as medicaments.
ES8801213A1 (en) * 1984-10-25 1988-01-01 Hoechst Roussel Pharma 9-Amino-1,2,3,4-tetrahydroacridin-1-ol and related compounds, a process for their preparation and their use as medicaments.
ES8802383A1 (en) * 1984-10-25 1988-05-16 Hoechst Roussel Pharma 9-Amino-1,2,3,4-tetrahydroacridin-1-ol and related compounds, a process for their preparation and their use as medicaments.
EP0311303A2 (en) * 1987-10-05 1989-04-12 Pfizer Inc. 4-aminopyridine derivatives
EP0449172A1 (en) * 1990-03-29 1991-10-02 Hoechst-Roussel Pharmaceuticals Incorporated A method of reducing a carbonyl containing acridine
EP0499231A1 (en) * 1991-02-13 1992-08-19 Hoechst-Roussel Pharmaceuticals Incorporated 9-Aminotetrahydroacridines and related compounds, a process for their preparation and their use as medicaments

Also Published As

Publication number Publication date
ES2059263B1 (en) 1995-10-01

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20001102