ES2056728A1 - New derivatives of piperidyl and aminoalkyl with 5-HT4 receptor antagonistic activity - Google Patents
New derivatives of piperidyl and aminoalkyl with 5-HT4 receptor antagonistic activityInfo
- Publication number
- ES2056728A1 ES2056728A1 ES09202166A ES9202166A ES2056728A1 ES 2056728 A1 ES2056728 A1 ES 2056728A1 ES 09202166 A ES09202166 A ES 09202166A ES 9202166 A ES9202166 A ES 9202166A ES 2056728 A1 ES2056728 A1 ES 2056728A1
- Authority
- ES
- Spain
- Prior art keywords
- piperidyl
- aminoalkyl
- antagonistic activity
- receptor antagonistic
- new derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Abstract
New derivatives of piperidyl and aminoalkyl with 5-HT4 receptor antagonistic activity. Said derivatives have the formula X-CO-Y-Z (I), in which X is selected from the groups (a, b and c), in which the different symbols represent organic radicals Y represents O or NH and Z represents a group of formula (d) or (e) in which n1, n2 and q represent zero or a whole number and the remaining symbols represent organic radicals. These compounds have application in the treatment of gastrointestinal, cardiovascular and central nervous system disorders.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES9202166A ES2056728B1 (en) | 1992-10-28 | 1992-10-28 | NEW PIPERIDILE AND AMINOALKYL DERIVATIVES WITH ANTAGONIST ACTIVITY OF THE 5-HT4 RECEPTOR |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES9202166A ES2056728B1 (en) | 1992-10-28 | 1992-10-28 | NEW PIPERIDILE AND AMINOALKYL DERIVATIVES WITH ANTAGONIST ACTIVITY OF THE 5-HT4 RECEPTOR |
Publications (2)
Publication Number | Publication Date |
---|---|
ES2056728A1 true ES2056728A1 (en) | 1994-10-01 |
ES2056728B1 ES2056728B1 (en) | 1995-05-01 |
Family
ID=8278596
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES9202166A Expired - Lifetime ES2056728B1 (en) | 1992-10-28 | 1992-10-28 | NEW PIPERIDILE AND AMINOALKYL DERIVATIVES WITH ANTAGONIST ACTIVITY OF THE 5-HT4 RECEPTOR |
Country Status (1)
Country | Link |
---|---|
ES (1) | ES2056728B1 (en) |
Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB2125398A (en) * | 1982-06-29 | 1984-03-07 | Sandoz Ltd | Bridged piperidyl esters and amides |
EP0189002A2 (en) * | 1984-12-20 | 1986-07-30 | Sandoz Ag | Treatment of gastrointestinal disorders using 5-HT3 antagonists |
EP0200444A2 (en) * | 1985-04-27 | 1986-11-05 | Beecham Group Plc | Azabicyclononyl-indazole-carboxamide having 5-HT antagonist activity |
EP0429984A2 (en) * | 1989-11-17 | 1991-06-05 | Nisshin Flour Milling Co., Ltd. | Indole derivatives |
WO1993003725A1 (en) * | 1991-08-20 | 1993-03-04 | Smithkline Beecham Plc | 5-ht4 receptor antagonists |
-
1992
- 1992-10-28 ES ES9202166A patent/ES2056728B1/en not_active Expired - Lifetime
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB2125398A (en) * | 1982-06-29 | 1984-03-07 | Sandoz Ltd | Bridged piperidyl esters and amides |
EP0189002A2 (en) * | 1984-12-20 | 1986-07-30 | Sandoz Ag | Treatment of gastrointestinal disorders using 5-HT3 antagonists |
EP0200444A2 (en) * | 1985-04-27 | 1986-11-05 | Beecham Group Plc | Azabicyclononyl-indazole-carboxamide having 5-HT antagonist activity |
EP0429984A2 (en) * | 1989-11-17 | 1991-06-05 | Nisshin Flour Milling Co., Ltd. | Indole derivatives |
WO1993003725A1 (en) * | 1991-08-20 | 1993-03-04 | Smithkline Beecham Plc | 5-ht4 receptor antagonists |
Also Published As
Publication number | Publication date |
---|---|
ES2056728B1 (en) | 1995-05-01 |
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