ES2051898T3 - PHARMACEUTICAL COMPOSITION FOR 4-AROILIMIDAZOLE-2-ONAS. - Google Patents

PHARMACEUTICAL COMPOSITION FOR 4-AROILIMIDAZOLE-2-ONAS.

Info

Publication number
ES2051898T3
ES2051898T3 ES89101268T ES89101268T ES2051898T3 ES 2051898 T3 ES2051898 T3 ES 2051898T3 ES 89101268 T ES89101268 T ES 89101268T ES 89101268 T ES89101268 T ES 89101268T ES 2051898 T3 ES2051898 T3 ES 2051898T3
Authority
ES
Spain
Prior art keywords
aroilimidazole
pharmaceutical composition
onas
pharmaceutically acceptable
composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES89101268T
Other languages
Spanish (es)
Inventor
Jack Domet
Douglas W Danielson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharmaceuticals Inc
Original Assignee
Merrell Dow Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharmaceuticals Inc filed Critical Merrell Dow Pharmaceuticals Inc
Application granted granted Critical
Publication of ES2051898T3 publication Critical patent/ES2051898T3/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Cardiology (AREA)
  • Pulmonology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

SE PROPORCIONA UNA COMPOSICION FARMACEUTICA LIQUIDA QUE COMPRENDE: A) UNA CANTIDAD EFECTIVA DE 4 - AROILIMIDAZOL - 2 - ONA O UNA SAL SUYA FARMACEUTICAMENTE ACEPTABLE, Y B) UNO O MAS TENSIOACTIVOS NO IONICOS FARMACEUTICAMENTE ACEPTABLES EN PROPORCION DEL 30 AL 99% EN PESO DE LA COMPOSICION, Y OPCIONALMENTE CONTIENE ADEMAS UNO O MAS EXCIPIENTES, FARMACEUTICAMENTE ACEPTABLES, DIFERENTES DE LOS TENSIOACTIVOS NO IONICOS EN CANTIDAD TOTAL QUE PUEDE LLEGAR HASTA EL 45% EN PESO DE LA COMPOSICION.A LIQUID PHARMACEUTICAL COMPOSITION IS PROVIDED, INCLUDING: A) AN EFFECTIVE AMOUNT OF 4 - AROILIMIDAZOLE - 2 - ONA OR ONE OF ITS PHARMACEUTICALLY ACCEPTABLE, NON-IONIC PHARMACEUTICALLY ACCEPTABLE 30 COMPOSITION, AND OPTIONALLY CONTAINS FURTHER ONE OR MORE EXCIPIENTS, PHARMACEUTICALLY ACCEPTABLE, DIFFERENT FROM THE TOTAL NON-IONIC SURFACTANTS THAT MAY REACH UP TO 45% BY WEIGHT OF THE COMPOSITION.

ES89101268T 1988-01-29 1989-01-25 PHARMACEUTICAL COMPOSITION FOR 4-AROILIMIDAZOLE-2-ONAS. Expired - Lifetime ES2051898T3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US14980388A 1988-01-29 1988-01-29

Publications (1)

Publication Number Publication Date
ES2051898T3 true ES2051898T3 (en) 1994-07-01

Family

ID=22531858

Family Applications (1)

Application Number Title Priority Date Filing Date
ES89101268T Expired - Lifetime ES2051898T3 (en) 1988-01-29 1989-01-25 PHARMACEUTICAL COMPOSITION FOR 4-AROILIMIDAZOLE-2-ONAS.

Country Status (17)

Country Link
EP (1) EP0326103B1 (en)
JP (1) JPH01226817A (en)
KR (1) KR890011594A (en)
CN (1) CN1035242A (en)
AR (1) AR241632A1 (en)
AT (1) ATE78161T1 (en)
AU (1) AU611757B2 (en)
DE (1) DE68902056T2 (en)
DK (1) DK169566B1 (en)
ES (1) ES2051898T3 (en)
GR (1) GR3005792T3 (en)
HU (1) HUT49282A (en)
IE (1) IE62426B1 (en)
IL (1) IL89049A0 (en)
NZ (1) NZ227700A (en)
PT (1) PT89561B (en)
ZA (1) ZA89552B (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2119748T3 (en) * 1990-03-23 1998-10-16 Yoshitomi Pharmaceutical PHARMACEUTICAL COMPOSITION CONTAINING A PHARMACEUTICALLY SOLUBLE IN WATER.
WO2005058280A2 (en) * 2003-12-12 2005-06-30 Myogen, Inc. Enoximone formulations and their use in the treatment of cardiac hypertrophy and heart failure
EP1776108A1 (en) * 2004-06-23 2007-04-25 Myogen, Inc. Enoximone formulations and their use in the treatment of pde-iii mediated diseases
EP2581082B1 (en) 2011-10-10 2015-12-30 Carinopharm GmbH Pharmaceutical composition for treating status asthmaticus

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4405635A (en) * 1979-06-18 1983-09-20 Merrell Dow Pharmaceuticals Inc. 4-Aroylimidazol-2-ones and their use as pharmaceuticals
EP0031603A1 (en) * 1979-12-31 1981-07-08 American Cyanamid Company Pharmaceutical composition of matter
NZ197796A (en) * 1980-08-04 1984-11-09 Merck & Co Inc Stabilised aqueous formulations containing ivermectin
DE3307422A1 (en) * 1983-03-03 1984-09-06 Bayer Ag, 5090 Leverkusen LIQUID PREPARATIONS OF DIHYDROPYRIDINES, A METHOD FOR THE PRODUCTION THEREOF AND THEIR USE IN THE FIGHT AGAINST DISEASES
EP0179583A1 (en) * 1984-10-04 1986-04-30 Merck & Co. Inc. A system for enhancing the water dissolution rate and solubility of poorly soluble drugs

Also Published As

Publication number Publication date
DE68902056D1 (en) 1992-08-20
CN1035242A (en) 1989-09-06
IL89049A0 (en) 1989-08-15
HUT49282A (en) 1989-09-28
ZA89552B (en) 1989-10-25
IE890275L (en) 1989-07-29
JPH01226817A (en) 1989-09-11
GR3005792T3 (en) 1993-06-07
KR890011594A (en) 1989-08-21
AU611757B2 (en) 1991-06-20
DK37589D0 (en) 1989-01-27
ATE78161T1 (en) 1992-08-15
DE68902056T2 (en) 1992-12-03
AU2876889A (en) 1989-08-03
AR241632A1 (en) 1992-10-30
IE62426B1 (en) 1995-02-08
NZ227700A (en) 1990-09-26
DK169566B1 (en) 1994-12-05
PT89561A (en) 1989-10-04
EP0326103A1 (en) 1989-08-02
EP0326103B1 (en) 1992-07-15
PT89561B (en) 1994-01-31
DK37589A (en) 1989-07-30

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