ES2046122A1 - Purified human seric albumen prepn - by ultra filtration, dia-filtration, adsorption on ion exchange resin, concn by further ultra-filtration, stabilisation, pasteurisation etc. - Google Patents

Purified human seric albumen prepn - by ultra filtration, dia-filtration, adsorption on ion exchange resin, concn by further ultra-filtration, stabilisation, pasteurisation etc.

Info

Publication number
ES2046122A1
ES2046122A1 ES9201153A ES9201153A ES2046122A1 ES 2046122 A1 ES2046122 A1 ES 2046122A1 ES 9201153 A ES9201153 A ES 9201153A ES 9201153 A ES9201153 A ES 9201153A ES 2046122 A1 ES2046122 A1 ES 2046122A1
Authority
ES
Spain
Prior art keywords
filtration
ultra
concn
pasteurisation
stabilisation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES9201153A
Other languages
Spanish (es)
Other versions
ES2046122B1 (en
Inventor
Debart Ristol
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Grifols SA
Original Assignee
Grifols SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Grifols SA filed Critical Grifols SA
Priority to ES9201153A priority Critical patent/ES2046122B1/en
Publication of ES2046122A1 publication Critical patent/ES2046122A1/en
Application granted granted Critical
Publication of ES2046122B1 publication Critical patent/ES2046122B1/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

The process consists of (a) adjusting the pH of a soln or plasma fraction rich in albumen; (b) concn and washing by ultra-filtration; (c) dia-filtration with cold water injection; (d) adjusting the pH to acid and adsorption on ion exchange resin; (e) filtration, clarification and adjustment to neutral pH; (f) concn by ultra-filtration; (g) final adjustment and stabilisation, opt with heat treatment and (h) dispensing into doses, pasteurisation and a quarantine phase.
ES9201153A 1992-06-04 1992-06-04 PROCEDURE FOR THE OBTAINING OF PURIFIED HUMAN SERIC ALBUMINE. Expired - Fee Related ES2046122B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
ES9201153A ES2046122B1 (en) 1992-06-04 1992-06-04 PROCEDURE FOR THE OBTAINING OF PURIFIED HUMAN SERIC ALBUMINE.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES9201153A ES2046122B1 (en) 1992-06-04 1992-06-04 PROCEDURE FOR THE OBTAINING OF PURIFIED HUMAN SERIC ALBUMINE.

Publications (2)

Publication Number Publication Date
ES2046122A1 true ES2046122A1 (en) 1994-01-16
ES2046122B1 ES2046122B1 (en) 1994-10-01

Family

ID=8277213

Family Applications (1)

Application Number Title Priority Date Filing Date
ES9201153A Expired - Fee Related ES2046122B1 (en) 1992-06-04 1992-06-04 PROCEDURE FOR THE OBTAINING OF PURIFIED HUMAN SERIC ALBUMINE.

Country Status (1)

Country Link
ES (1) ES2046122B1 (en)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2473341A1 (en) * 1980-01-10 1981-07-17 Toyo Soda Mfg Co Ltd SEPARATION OF PLASMA ALBUMIN BY ULTRAFILTRATION
EP0121468A2 (en) * 1983-04-01 1984-10-10 Rhone-Poulenc Recherches Process for the fractionation of blood plasma
EP0319067A1 (en) * 1987-11-18 1989-06-07 Gist-Brocades N.V. Process for the purification of serum albumin

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2473341A1 (en) * 1980-01-10 1981-07-17 Toyo Soda Mfg Co Ltd SEPARATION OF PLASMA ALBUMIN BY ULTRAFILTRATION
EP0121468A2 (en) * 1983-04-01 1984-10-10 Rhone-Poulenc Recherches Process for the fractionation of blood plasma
EP0319067A1 (en) * 1987-11-18 1989-06-07 Gist-Brocades N.V. Process for the purification of serum albumin

Also Published As

Publication number Publication date
ES2046122B1 (en) 1994-10-01

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Effective date: 20141120