ES2043567T1 - A CONTROLLED RELEASE PHARMACEUTICAL COMPOSITION FOR ORAL USE CONTAINING NON-STEROID ANTI-INFLAMMATORY DRUGS. - Google Patents
A CONTROLLED RELEASE PHARMACEUTICAL COMPOSITION FOR ORAL USE CONTAINING NON-STEROID ANTI-INFLAMMATORY DRUGS.Info
- Publication number
- ES2043567T1 ES2043567T1 ES91912626T ES91912626T ES2043567T1 ES 2043567 T1 ES2043567 T1 ES 2043567T1 ES 91912626 T ES91912626 T ES 91912626T ES 91912626 T ES91912626 T ES 91912626T ES 2043567 T1 ES2043567 T1 ES 2043567T1
- Authority
- ES
- Spain
- Prior art keywords
- controlled release
- pharmaceutical composition
- steroid anti
- inflammatory drugs
- oral use
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000013270 controlled release Methods 0.000 title abstract 3
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 229940021182 non-steroidal anti-inflammatory drug Drugs 0.000 title 1
- 239000004480 active ingredient Substances 0.000 abstract 2
- 239000003814 drug Substances 0.000 abstract 2
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 230000015556 catabolic process Effects 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000007903 gelatin capsule Substances 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 229940126601 medicinal product Drugs 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000006187 pill Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
UNA COMPOSICION FARMACEUTICA PARA LA LIBERACION CONTROLADA DE MEDICAMENTOS ANTIINFLAMATORIOS NO ESTEROIDALES, QUE PROPORCIONA UNOS NIVELES PLASMATICOS EFECTIVOS DE MEDICAMENTO DURANTE 12 A 24 HORAS. DICHA COMPOSICION DE LIBERACION CONTROLADA INCLUYE: A) 3 O 4 UNIDADES DE DOSIFICACION (NUCLEOS) QUE CONTIENE 1/3 O 1/4 RESPECTIVAMENTE DE LA DOSIS TOTAL DE MEDICAMENTO, CONSISTIENDO DICHAS UNIDADES UNICAS DE DOSIFICACION EN PASTILLAS QUE SE PUEDEN DISGREGAR Y/O EN PASTILLAS QUE NO SE PUEDEN DISGREGAR, QUE INCLUYEN EL INGREDIENTE ACTIVO ASI COMO MATERIALES POLIMERICOS HIDROFILICOS QUE PUEDEN LIBERAR GRADUALMENTE LOS INGREDIENTES ACTIVOS, Y (B) CAPSULAS DE GELATINA DURAS QUE CONTIENEN 3 O 4 UNIDADES DE LIBERACION.A PHARMACEUTICAL COMPOSITION FOR THE CONTROLLED RELEASE OF NON-STEROID ANTI-INFLAMMATORY MEDICINES, WHICH PROVIDES EFFECTIVE PLASMATIC LEVELS OF MEDICATION FOR 12 TO 24 HOURS. SUCH CONTROLLED RELEASE COMPOSITION INCLUDES: A) 3 OR 4 DOSING UNITS (CORES) CONTAINING 1/3 OR 1/4 RESPECTIVELY OF THE TOTAL DOSE OF THE MEDICINAL PRODUCT, CONSISTING OF SINGLE UNITS OF DOSING IN PILLS THAT CAN BE DISGREGATED AND / OR IN PADS THAT CANNOT BE BREAKDOWN, INCLUDING ACTIVE INGREDIENT AS WELL AS HYDROPHILIC POLYMERIC MATERIALS THAT CAN GRADUALLY RELEASE ACTIVE INGREDIENTS, AND (B) HARD GELATIN CAPSULES CONTAINING 3 OR 4 UNITS OF FREE.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT02094390A IT1243341B (en) | 1990-07-13 | 1990-07-13 | PHARMACEUTICAL COMPOSITION FOR ORAL USE WITH MODIFIED RELEASE OF NON STEROID ANTI-INFLAMMATORS |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2043567T1 true ES2043567T1 (en) | 1994-01-01 |
Family
ID=11174413
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES91912626T Pending ES2043567T1 (en) | 1990-07-13 | 1991-07-04 | A CONTROLLED RELEASE PHARMACEUTICAL COMPOSITION FOR ORAL USE CONTAINING NON-STEROID ANTI-INFLAMMATORY DRUGS. |
Country Status (7)
Country | Link |
---|---|
EP (1) | EP0491911A1 (en) |
AU (1) | AU8186291A (en) |
CA (1) | CA2066751A1 (en) |
ES (1) | ES2043567T1 (en) |
GR (1) | GR930300020T1 (en) |
IT (1) | IT1243341B (en) |
WO (1) | WO1992000730A1 (en) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1993017673A1 (en) * | 1992-03-03 | 1993-09-16 | Top Gold Pty., Limited | Sustained release analgesics |
US5922722A (en) * | 1996-11-12 | 1999-07-13 | Merck & Co., Inc. | Alpha 1a adrenergic receptor antagonists |
DE19718012C1 (en) * | 1997-04-29 | 1998-10-08 | Jenapharm Gmbh | Process for the production of orally applicable solid pharmaceutical forms with controlled release of active substances |
DE19901683B4 (en) * | 1999-01-18 | 2005-07-21 | Grünenthal GmbH | Controlled-release analgesic |
EP2070520A1 (en) | 2007-12-11 | 2009-06-17 | LEK Pharmaceuticals D.D. | Pharmaceutical composition comprising at least one active agent and a binder, which swells in an acidic media |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2021147A1 (en) * | 1970-04-30 | 1971-11-11 | Christian Brunnengraeber Chem | Medicinal capsule contg separate units |
US4773907A (en) * | 1982-12-20 | 1988-09-27 | Alza Corporation | Primary delivery system comprising secondary dosage form |
GB2176999B (en) * | 1985-06-22 | 1989-07-12 | Stanley Stewart Davis | Sustained release medicament |
IT1230576B (en) * | 1988-10-20 | 1991-10-28 | Angeli Inst Spa | ORAL PHARMACEUTICAL FORMULATIONS WITH SELECTIVE LIBERATION IN THE COLON |
-
1990
- 1990-07-13 IT IT02094390A patent/IT1243341B/en active IP Right Grant
-
1991
- 1991-07-04 WO PCT/EP1991/001246 patent/WO1992000730A1/en not_active Application Discontinuation
- 1991-07-04 AU AU81862/91A patent/AU8186291A/en not_active Abandoned
- 1991-07-04 ES ES91912626T patent/ES2043567T1/en active Pending
- 1991-07-04 EP EP19910912626 patent/EP0491911A1/en not_active Withdrawn
- 1991-07-04 CA CA002066751A patent/CA2066751A1/en not_active Abandoned
-
1993
- 1993-04-28 GR GR930300020T patent/GR930300020T1/el unknown
Also Published As
Publication number | Publication date |
---|---|
IT9020943A1 (en) | 1992-01-13 |
CA2066751A1 (en) | 1992-01-14 |
GR930300020T1 (en) | 1993-04-28 |
AU8186291A (en) | 1992-02-04 |
IT9020943A0 (en) | 1990-07-13 |
IT1243341B (en) | 1994-06-10 |
EP0491911A1 (en) | 1992-07-01 |
WO1992000730A1 (en) | 1992-01-23 |
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