ES2043567T1 - A CONTROLLED RELEASE PHARMACEUTICAL COMPOSITION FOR ORAL USE CONTAINING NON-STEROID ANTI-INFLAMMATORY DRUGS. - Google Patents

A CONTROLLED RELEASE PHARMACEUTICAL COMPOSITION FOR ORAL USE CONTAINING NON-STEROID ANTI-INFLAMMATORY DRUGS.

Info

Publication number
ES2043567T1
ES2043567T1 ES91912626T ES91912626T ES2043567T1 ES 2043567 T1 ES2043567 T1 ES 2043567T1 ES 91912626 T ES91912626 T ES 91912626T ES 91912626 T ES91912626 T ES 91912626T ES 2043567 T1 ES2043567 T1 ES 2043567T1
Authority
ES
Spain
Prior art keywords
controlled release
pharmaceutical composition
steroid anti
inflammatory drugs
oral use
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
ES91912626T
Other languages
Spanish (es)
Inventor
Ubaldo Conte
Lauretta Univ Di Pavia D Maggi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
L C PHARCHEM Ltd
Original Assignee
L C PHARCHEM Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by L C PHARCHEM Ltd filed Critical L C PHARCHEM Ltd
Publication of ES2043567T1 publication Critical patent/ES2043567T1/en
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4808Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

UNA COMPOSICION FARMACEUTICA PARA LA LIBERACION CONTROLADA DE MEDICAMENTOS ANTIINFLAMATORIOS NO ESTEROIDALES, QUE PROPORCIONA UNOS NIVELES PLASMATICOS EFECTIVOS DE MEDICAMENTO DURANTE 12 A 24 HORAS. DICHA COMPOSICION DE LIBERACION CONTROLADA INCLUYE: A) 3 O 4 UNIDADES DE DOSIFICACION (NUCLEOS) QUE CONTIENE 1/3 O 1/4 RESPECTIVAMENTE DE LA DOSIS TOTAL DE MEDICAMENTO, CONSISTIENDO DICHAS UNIDADES UNICAS DE DOSIFICACION EN PASTILLAS QUE SE PUEDEN DISGREGAR Y/O EN PASTILLAS QUE NO SE PUEDEN DISGREGAR, QUE INCLUYEN EL INGREDIENTE ACTIVO ASI COMO MATERIALES POLIMERICOS HIDROFILICOS QUE PUEDEN LIBERAR GRADUALMENTE LOS INGREDIENTES ACTIVOS, Y (B) CAPSULAS DE GELATINA DURAS QUE CONTIENEN 3 O 4 UNIDADES DE LIBERACION.A PHARMACEUTICAL COMPOSITION FOR THE CONTROLLED RELEASE OF NON-STEROID ANTI-INFLAMMATORY MEDICINES, WHICH PROVIDES EFFECTIVE PLASMATIC LEVELS OF MEDICATION FOR 12 TO 24 HOURS. SUCH CONTROLLED RELEASE COMPOSITION INCLUDES: A) 3 OR 4 DOSING UNITS (CORES) CONTAINING 1/3 OR 1/4 RESPECTIVELY OF THE TOTAL DOSE OF THE MEDICINAL PRODUCT, CONSISTING OF SINGLE UNITS OF DOSING IN PILLS THAT CAN BE DISGREGATED AND / OR IN PADS THAT CANNOT BE BREAKDOWN, INCLUDING ACTIVE INGREDIENT AS WELL AS HYDROPHILIC POLYMERIC MATERIALS THAT CAN GRADUALLY RELEASE ACTIVE INGREDIENTS, AND (B) HARD GELATIN CAPSULES CONTAINING 3 OR 4 UNITS OF FREE.

ES91912626T 1990-07-13 1991-07-04 A CONTROLLED RELEASE PHARMACEUTICAL COMPOSITION FOR ORAL USE CONTAINING NON-STEROID ANTI-INFLAMMATORY DRUGS. Pending ES2043567T1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT02094390A IT1243341B (en) 1990-07-13 1990-07-13 PHARMACEUTICAL COMPOSITION FOR ORAL USE WITH MODIFIED RELEASE OF NON STEROID ANTI-INFLAMMATORS

Publications (1)

Publication Number Publication Date
ES2043567T1 true ES2043567T1 (en) 1994-01-01

Family

ID=11174413

Family Applications (1)

Application Number Title Priority Date Filing Date
ES91912626T Pending ES2043567T1 (en) 1990-07-13 1991-07-04 A CONTROLLED RELEASE PHARMACEUTICAL COMPOSITION FOR ORAL USE CONTAINING NON-STEROID ANTI-INFLAMMATORY DRUGS.

Country Status (7)

Country Link
EP (1) EP0491911A1 (en)
AU (1) AU8186291A (en)
CA (1) CA2066751A1 (en)
ES (1) ES2043567T1 (en)
GR (1) GR930300020T1 (en)
IT (1) IT1243341B (en)
WO (1) WO1992000730A1 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993017673A1 (en) * 1992-03-03 1993-09-16 Top Gold Pty., Limited Sustained release analgesics
US5922722A (en) * 1996-11-12 1999-07-13 Merck & Co., Inc. Alpha 1a adrenergic receptor antagonists
DE19718012C1 (en) * 1997-04-29 1998-10-08 Jenapharm Gmbh Process for the production of orally applicable solid pharmaceutical forms with controlled release of active substances
DE19901683B4 (en) * 1999-01-18 2005-07-21 Grünenthal GmbH Controlled-release analgesic
EP2070520A1 (en) 2007-12-11 2009-06-17 LEK Pharmaceuticals D.D. Pharmaceutical composition comprising at least one active agent and a binder, which swells in an acidic media

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2021147A1 (en) * 1970-04-30 1971-11-11 Christian Brunnengraeber Chem Medicinal capsule contg separate units
US4773907A (en) * 1982-12-20 1988-09-27 Alza Corporation Primary delivery system comprising secondary dosage form
GB2176999B (en) * 1985-06-22 1989-07-12 Stanley Stewart Davis Sustained release medicament
IT1230576B (en) * 1988-10-20 1991-10-28 Angeli Inst Spa ORAL PHARMACEUTICAL FORMULATIONS WITH SELECTIVE LIBERATION IN THE COLON

Also Published As

Publication number Publication date
IT9020943A1 (en) 1992-01-13
CA2066751A1 (en) 1992-01-14
GR930300020T1 (en) 1993-04-28
AU8186291A (en) 1992-02-04
IT9020943A0 (en) 1990-07-13
IT1243341B (en) 1994-06-10
EP0491911A1 (en) 1992-07-01
WO1992000730A1 (en) 1992-01-23

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