ES2042364B1 - PROCEDURE FOR OBTAINING NEW PLATINUM DERIVATIVES WITH AMINOPYROLIDINES. - Google Patents

PROCEDURE FOR OBTAINING NEW PLATINUM DERIVATIVES WITH AMINOPYROLIDINES.

Info

Publication number
ES2042364B1
ES2042364B1 ES09101355A ES9101355A ES2042364B1 ES 2042364 B1 ES2042364 B1 ES 2042364B1 ES 09101355 A ES09101355 A ES 09101355A ES 9101355 A ES9101355 A ES 9101355A ES 2042364 B1 ES2042364 B1 ES 2042364B1
Authority
ES
Spain
Prior art keywords
aminopyrolidines
procedure
obtaining new
platinum derivatives
new platinum
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
ES09101355A
Other languages
Spanish (es)
Other versions
ES2042364A1 (en
Inventor
Ambros Rafael Foguet
Camarena Federico Sampedro
Pujol Antonio M Molins
Castejon Jose Ignacio Ruiz
Bel M Pilar Santalo
De Galgas Joaquin Bonal
Hernandez Jose A Ortiz
Barenys Josep M Castello
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ferrer Internacional SA
Original Assignee
Ferrer Internacional SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ferrer Internacional SA filed Critical Ferrer Internacional SA
Priority to ES09101355A priority Critical patent/ES2042364B1/en
Priority to ES09201002A priority patent/ES2056721B1/en
Priority to KR1019920009568A priority patent/KR950007337B1/en
Priority to ZA924044A priority patent/ZA924044B/en
Priority to CA002070508A priority patent/CA2070508A1/en
Priority to EP92109480A priority patent/EP0517225A1/en
Priority to JP4145925A priority patent/JPH05178872A/en
Priority to IE173292A priority patent/IE921732A1/en
Publication of ES2042364A1 publication Critical patent/ES2042364A1/en
Application granted granted Critical
Publication of ES2042364B1 publication Critical patent/ES2042364B1/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Abstract

PROCEDIMIENTO DE OBTENCION DE NUEVOS DERIVADOS DE PLATINO CON AMINOPIRROLIDINAS. CONSISTE EN EL TRATAMIENTO DE UNA DISOLUCION DE TETRACLOROPLATINITO POTASICO EN AGUA CON LA AMINOPIRROLIDINA CORRESPONDIENTE (II). TANTO EN LOS COMPUESTOS DE LA PRESENTE INVENCION (I) COMO EN LOS INTERMEDIOS (II), R Y RSI1 SC SON ALQUILO CONTENIENDO DE 1 A 2 ATOMOS DE CARBONO. LOS COMPUESTOS (I) PRESENTAN ACTIVIDAD ANTITUMORAL Y SON UTILES EN EL TRATAMIENTO DE DIVERSOS TUMORES MALIGNOS.PROCEDURE FOR OBTAINING NEW PLATINUM DERIVATIVES WITH AMINOPYROLIDINES. IT CONSISTS IN THE TREATMENT OF A SOLUTION OF POTASSIC TETRACHLOROPLATINITE IN WATER WITH THE CORRESPONDING AMINOPYROLIDINE (II). BOTH IN THE COMPOUNDS OF THE PRESENT INVENTION (I) AND IN THE INTERMEDIATES (II), R AND RSI1 SC ARE ALKYL CONTAINING 1 TO 2 CARBON ATOMS. COMPOUNDS (I) PRESENT ANTITUMORAL ACTIVITY AND ARE USEFUL IN THE TREATMENT OF VARIOUS MALIGNANT TUMORS.

ES09101355A 1991-06-05 1991-06-05 PROCEDURE FOR OBTAINING NEW PLATINUM DERIVATIVES WITH AMINOPYROLIDINES. Expired - Fee Related ES2042364B1 (en)

Priority Applications (8)

Application Number Priority Date Filing Date Title
ES09101355A ES2042364B1 (en) 1991-06-05 1991-06-05 PROCEDURE FOR OBTAINING NEW PLATINUM DERIVATIVES WITH AMINOPYROLIDINES.
ES09201002A ES2056721B1 (en) 1991-06-05 1992-05-14 IMPROVEMENTS IN THE PURPOSE OF THE PATENT OF INVENTION N {9101355 THAT REFERS TO THE PROCEDURE FOR OBTAINING NEW PLATINUM DERIVATIVES WITH AMINOPYROLIDINES.
KR1019920009568A KR950007337B1 (en) 1991-06-05 1992-06-02 Aminopyrrolidine platinum compounds and a process for preparing them
ZA924044A ZA924044B (en) 1991-06-05 1992-06-03 Aminopyrrolidine platinum compounds,process for their production and pharmaceutical compositions containing them
CA002070508A CA2070508A1 (en) 1991-06-05 1992-06-04 Aminopyrrolidine platinum compounds and process for their production
EP92109480A EP0517225A1 (en) 1991-06-05 1992-06-04 Aminopyrrolidine platinum compounds, a process for preparing them and pharmaceutical compositions containing them
JP4145925A JPH05178872A (en) 1991-06-05 1992-06-05 Aminopyrrolidine platinum compound, its preparation and antitumor agent containing it
IE173292A IE921732A1 (en) 1991-06-05 1992-07-01 Aminopyrrolidine platinum compounds, a process for preparing¹them and pharmaceutical compositions containing them

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES09101355A ES2042364B1 (en) 1991-06-05 1991-06-05 PROCEDURE FOR OBTAINING NEW PLATINUM DERIVATIVES WITH AMINOPYROLIDINES.

Publications (2)

Publication Number Publication Date
ES2042364A1 ES2042364A1 (en) 1993-12-01
ES2042364B1 true ES2042364B1 (en) 1994-07-16

Family

ID=8272607

Family Applications (1)

Application Number Title Priority Date Filing Date
ES09101355A Expired - Fee Related ES2042364B1 (en) 1991-06-05 1991-06-05 PROCEDURE FOR OBTAINING NEW PLATINUM DERIVATIVES WITH AMINOPYROLIDINES.

Country Status (2)

Country Link
ES (1) ES2042364B1 (en)
ZA (1) ZA924044B (en)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE86967T1 (en) * 1988-01-09 1993-04-15 Asta Medica Ag 1,2-BIS(AMINOMETHYL)CYCLOBUTANE PLATINUM COMPLEXES.
JPH01294683A (en) * 1988-02-04 1989-11-28 Kanebo Ltd Novel platinum complex, antitumor agent containing said complex as active ingredient and intermediate for preparing the same compound
AT392273B (en) * 1988-04-07 1991-02-25 Chugai Pharmaceutical Co Ltd METHOD FOR PRODUCING PLATINUM COMPLEXES

Also Published As

Publication number Publication date
ES2042364A1 (en) 1993-12-01
ZA924044B (en) 1993-02-24

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20000201