ES2042061T3 - Procedimiento para la obtencion de derivados carbamoilados del acido hidroxamico. - Google Patents

Procedimiento para la obtencion de derivados carbamoilados del acido hidroxamico.

Info

Publication number
ES2042061T3
ES2042061T3 ES198989810405T ES89810405T ES2042061T3 ES 2042061 T3 ES2042061 T3 ES 2042061T3 ES 198989810405 T ES198989810405 T ES 198989810405T ES 89810405 T ES89810405 T ES 89810405T ES 2042061 T3 ES2042061 T3 ES 2042061T3
Authority
ES
Spain
Prior art keywords
iii
formula
iron
carbamoyl
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES198989810405T
Other languages
English (en)
Inventor
Heinrich Dr. Peter
Theophile Moerker
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy AG filed Critical Ciba Geigy AG
Application granted granted Critical
Publication of ES2042061T3 publication Critical patent/ES2042061T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/60—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups having oxygen atoms of carbamate groups bound to nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/02—Antidotes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Toxicology (AREA)
  • Obesity (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyridine Compounds (AREA)

Abstract

SE DESCRIBEN DERIVADOS DE O - CARBAMOILO DE DESFERRIOXAMINA B DE LA FORMULA(I), DONDE LOS SIMBOLOS A1, A2, A3, AC, B TIENEN LOS SIGNIFICADOS DADOS EN LA DESCRIPCION. ESTOS COMPUESTOS FORMAN FUERTES COMPLEJOS FE(III) Y AL EN LAS CELULAS VIVAS. SON PARA EL TRATAMIENTO DE SUSTANCIAS QUE PRODUCEN ENFERMEDADES EN SAGRE CALIENTE, LAS CUALES POR UNA SOBRE EDULCORACION FORMA UNA FE(III) O UN AL CON CUERPOS QUE CUELGAN JUNTO O POR FE(III) INDEPENDIEN TE DE LOS ORGANISMOS PATOGENOS. LOS COMPUESTOS DE LA FORMULA(I) SE OBTIENEN P.E. POR TRANSFORMACIONCONVENCIONAL DE DESFERRIOXAMINA B N - SUSTITUIDO CON UN ESTER ACIDO ISOCIANOTOALCANO.
ES198989810405T 1988-06-08 1989-05-30 Procedimiento para la obtencion de derivados carbamoilados del acido hidroxamico. Expired - Lifetime ES2042061T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH218188 1988-06-08

Publications (1)

Publication Number Publication Date
ES2042061T3 true ES2042061T3 (es) 1993-12-01

Family

ID=4227782

Family Applications (1)

Application Number Title Priority Date Filing Date
ES198989810405T Expired - Lifetime ES2042061T3 (es) 1988-06-08 1989-05-30 Procedimiento para la obtencion de derivados carbamoilados del acido hidroxamico.

Country Status (8)

Country Link
EP (1) EP0346281B1 (es)
JP (1) JPH0242052A (es)
AT (1) ATE77368T1 (es)
DE (1) DE58901673D1 (es)
DK (1) DK278689A (es)
ES (1) ES2042061T3 (es)
GR (1) GR3005324T3 (es)
PT (1) PT90759B (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6140305A (en) 1996-04-04 2000-10-31 Bio-Rad Laboratories, Inc. Hereditary hemochromatosis gene products
US7026116B1 (en) 1996-04-04 2006-04-11 Bio-Rad Laboratories, Inc. Polymorphisms in the region of the human hemochromatosis gene
US6849399B1 (en) 1996-05-23 2005-02-01 Bio-Rad Laboratories, Inc. Methods and compositions for diagnosis and treatment of iron misregulation diseases
US6391852B1 (en) 1997-06-13 2002-05-21 Bio-Rad Laboratories, Inc. Methods and compositions for diagnosis and treatment of iron overload diseases and iron deficiency diseases

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4684482A (en) * 1984-01-26 1987-08-04 Oral-D (L.P.) Orally effective ion chelators
ATE55375T1 (de) * 1984-12-19 1990-08-15 Ciba Geigy Ag Neue kohlensaeureester.
US4940811A (en) * 1986-12-09 1990-07-10 Ciba-Geigy Corporation N,N-disubstituted ureas and processes for their manufacture
MX12394A (es) * 1987-07-23 1993-12-01 Ciba Geigy Ag Procedimiento par la obtencion de carbamatos de polietilenglicol.

Also Published As

Publication number Publication date
DE58901673D1 (de) 1992-07-23
JPH0242052A (ja) 1990-02-13
EP0346281A1 (de) 1989-12-13
PT90759B (pt) 1994-10-31
EP0346281B1 (de) 1992-06-17
GR3005324T3 (es) 1993-05-24
DK278689D0 (da) 1989-06-07
PT90759A (pt) 1989-12-29
ATE77368T1 (de) 1992-07-15
DK278689A (da) 1989-12-09

Similar Documents

Publication Publication Date Title
DE69416501D1 (de) 2-propylvaleriansäure und 2-propylvalerian-säureamid-derivate und deren verwendung als antikonvulsive mittel
ZA889120B (en) A process for the preparation of optically active 3-demethylmevalonic acid derivatives,and intermediates
ES2042061T3 (es) Procedimiento para la obtencion de derivados carbamoilados del acido hidroxamico.
NO156370C (no) AnalogifremgangsmŸte ved fremstilling av terapeutisk virksomme polyolefiniske-alfa-alkyl-carboxylsyrer.
NO930596L (no) 4-amino-2-ureido-pyrimidin-5-karboksylsyreamider, fremgangsmaate for fremstilling derav, legemidler som inneholder forbindelsene og anvendelse derav
DK392686A (da) Kulsyremonoesterafledte n- og/eller o-acylater af desferrioxamin b og salte deraf
FI810145L (fi) Nya substituerade 1,8-dihydroxi-9-(10h)antracenoner foerfarande foer deras framstaellning och dessa foereningar innehaollande laekemedel
HU9502603D0 (en) Hydroxymethyl furazane carbocyclic acid derivatives and their use in the treatment of cardio-vascular conditions
DE69815380D1 (de) N,n'-bis (sulfonyl) hydrazine die als antineoplastische mittel nützlich sind
GR3005520T3 (es)
PT91145A (pt) Processo para a sintese de amino-acidos opticamente activos
SE7903971L (sv) Antitumordeoxiantracykliner
AT382614B (de) Verfahren zur herstellung neuer carbonsaeure-amido-thiolcarbamat-derivate
ES445301A1 (es) Un procedimiento para la preparacion de nuevos derivados de xantina.
DE69409799T2 (de) Herstellung von symmetrischen und unsymmetrischen disubstituierten n-cyandithioiminocarbonaten
SE7714525L (sv) Sett att framstella n-substituerade 2-aminocyklopent-1-en-1-ditiokarboxylsyror

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 346281

Country of ref document: ES