ES2041211A1 - Procedimiento para la obtencion de nuevos dihidro y tetrahidronaftalenos. - Google Patents
Procedimiento para la obtencion de nuevos dihidro y tetrahidronaftalenos.Info
- Publication number
- ES2041211A1 ES2041211A1 ES929200332A ES9200332A ES2041211A1 ES 2041211 A1 ES2041211 A1 ES 2041211A1 ES 929200332 A ES929200332 A ES 929200332A ES 9200332 A ES9200332 A ES 9200332A ES 2041211 A1 ES2041211 A1 ES 2041211A1
- Authority
- ES
- Spain
- Prior art keywords
- hydro
- derivs
- opt
- corresp
- tetra
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
PROCEDIMIENTO PARA LA OBTENCION DE DIHIDRO Y TETRAHIDRONAFTALENOS, DE FORMULA GENERAL I, EN DONDE RBS1 SC Y RBS2 SC SIGNIFICAN HIDROGENO, CIANO, NITRO, HALOGENO, HIDROXI O CRSI1-4 SC ALCOXI; RBS3 SC ES HIDROGENO O CSI1-4 SC ALQUILO; RBS4 SC ES CSI1-4 SC ALQUILO; RBS5 SC ES HIDROXILO O ACEITLOXI; RBS6 SC ES HIDROGENO; RSI7 SC-RSI8 SC JUNTOS FORMAN UN GRUPO TRIMETILENO O TETRAMETILENO OPCIONALMENTE SUSTITUIDO; RBS9 SC ES HIDROGENO O ALQUILO CSI1-6 SC ALQUILO; RBS10 SC ES HIDROXI, CSI1-6 SC ALCOXI, CSI1-6 SC ALQUILCARBONILOXI, AMINO O AMINO OPCIONALMENTE SUSTITUIDO; X ES OXIGENO O AZUFRE. EL PROCEDIMIENTO HACE REACCIONAR LA CORRESPONDIENTE NAFTALEN-1-ONA CON UN AGENTE REDUCTOR, COMO BOROHIDRURO SODICO, O CON UN HALOGENURO DE ALQUILMAGNESIO, Y OPCIONALMENTE SE ALQUILA O ACILA EL ALCOHOL OBTENIDO. LOS PRODUCTOS SON UTILES COMO REGULADORES DE LA CONTRACCION DE LA MUSCULATURA LISA EN LOS SISTEMAS CARDIOVASCULAR, BRONCOPULMONAR Y DIGESTIVO.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES9200332A ES2041211B1 (es) | 1992-02-17 | 1992-02-17 | Procedimiento para la obtencion de nuevos dihidro y tetrahidronaftalenos. |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES9200332A ES2041211B1 (es) | 1992-02-17 | 1992-02-17 | Procedimiento para la obtencion de nuevos dihidro y tetrahidronaftalenos. |
Publications (2)
Publication Number | Publication Date |
---|---|
ES2041211A1 true ES2041211A1 (es) | 1993-11-01 |
ES2041211B1 ES2041211B1 (es) | 1994-05-16 |
Family
ID=8276077
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES9200332A Expired - Fee Related ES2041211B1 (es) | 1992-02-17 | 1992-02-17 | Procedimiento para la obtencion de nuevos dihidro y tetrahidronaftalenos. |
Country Status (1)
Country | Link |
---|---|
ES (1) | ES2041211B1 (es) |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4510157A (en) * | 1982-12-27 | 1985-04-09 | Ayerst, Mckenna & Harrison, Inc. | 6,7,8,9-Tetrahydro-1H-benz(g)indol-8-amine derivatives |
EP0385658A1 (en) * | 1989-02-27 | 1990-09-05 | Eli Lilly And Company | Ring-substituted 2-amino 1,2,3,4-tetra-hydronaphthalenes and 3-aminochromanes |
EP0405344A2 (en) * | 1989-06-27 | 1991-01-02 | CHIESI FARMACEUTICI S.p.A. | 2-Amino-1,2,3,4,-tetrahydronaphthalene derivatives with cardiovascular activity, process for their preparation and pharmaceutical compositions containing them |
-
1992
- 1992-02-17 ES ES9200332A patent/ES2041211B1/es not_active Expired - Fee Related
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4510157A (en) * | 1982-12-27 | 1985-04-09 | Ayerst, Mckenna & Harrison, Inc. | 6,7,8,9-Tetrahydro-1H-benz(g)indol-8-amine derivatives |
EP0385658A1 (en) * | 1989-02-27 | 1990-09-05 | Eli Lilly And Company | Ring-substituted 2-amino 1,2,3,4-tetra-hydronaphthalenes and 3-aminochromanes |
EP0405344A2 (en) * | 1989-06-27 | 1991-01-02 | CHIESI FARMACEUTICI S.p.A. | 2-Amino-1,2,3,4,-tetrahydronaphthalene derivatives with cardiovascular activity, process for their preparation and pharmaceutical compositions containing them |
Also Published As
Publication number | Publication date |
---|---|
ES2041211B1 (es) | 1994-05-16 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD1A | Patent lapsed |
Effective date: 20000401 |