ES2024729A6 - Metodo de ensayar muestras desconocidas de fluido biologico para detectar peptidos formadores de canales de iones. - Google Patents
Metodo de ensayar muestras desconocidas de fluido biologico para detectar peptidos formadores de canales de iones.Info
- Publication number
- ES2024729A6 ES2024729A6 ES8903535A ES8903535A ES2024729A6 ES 2024729 A6 ES2024729 A6 ES 2024729A6 ES 8903535 A ES8903535 A ES 8903535A ES 8903535 A ES8903535 A ES 8903535A ES 2024729 A6 ES2024729 A6 ES 2024729A6
- Authority
- ES
- Spain
- Prior art keywords
- treatment
- composition
- biologically active
- active peptides
- certain anions
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- A61K38/1751—Bactericidal/permeability-increasing protein [BPI]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Gastroenterology & Hepatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Zoology (AREA)
- Urology & Nephrology (AREA)
- Biochemistry (AREA)
- Marine Sciences & Fisheries (AREA)
- Oncology (AREA)
- Biomedical Technology (AREA)
- Genetics & Genomics (AREA)
- Communicable Diseases (AREA)
- Biophysics (AREA)
- Hematology (AREA)
- Food Science & Technology (AREA)
- Pathology (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Toxicology (AREA)
- Microbiology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
Abstract
METODO DE ENSAYAR MUESTRAS DESCONOCIDAS DE FLUIDO BIOLOGICO PARA DETECTAR PEPTIDOS FORMADORES DE CANALES DE IONES. COMPRENDE PONER EN CONTACTO UNA PORCION DE UNA MUESTRA DESCONOCIDA CON UNA MUESTRA DE CELULAS DIANA SELECCIONADA ENTRE BACTERIAS, HONGOS, PROTOZOOS, CELULAS TUMORALES, CELULAS INFECTADAS POR VIRUS Y SIMILARES, MEDIAR LA ACTIVIDAD BIOLOGICA CONTRA ESTAS ULTIMAS, PONER EN CONTACTO OTRA PORCION DE DICHA MUESTRA DESCONOCIDA E ION FLUORURO CON OTRA MUESTRA DE CELULAS DIANA, MEDIAR LA ACTIVIDAD BIOLOGICA CONTRA ESTAS ULTIMAS Y COMPARAR AMBAS ACTIVIDADES BIOLOGICAS MEDIDAS PARA DETERMINAR LA PRESENCIA DE PEPTIDOS FORMADORAS DE CANALES DE IONES EN DICHA MUESTRA DESCONOCIDA. EL INVENTO ES UTIL PARA TRATAR AFECCIONES VIRICAS, TUMORALES, MICROBIANAS, PARASITARIAS Y OTRAS.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US26123788A | 1988-10-21 | 1988-10-21 | |
US35361889A | 1989-05-18 | 1989-05-18 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2024729A6 true ES2024729A6 (es) | 1992-03-01 |
Family
ID=26948475
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES8903535A Expired - Fee Related ES2024729A6 (es) | 1988-10-21 | 1989-10-20 | Metodo de ensayar muestras desconocidas de fluido biologico para detectar peptidos formadores de canales de iones. |
Country Status (13)
Country | Link |
---|---|
EP (1) | EP0441832B1 (es) |
JP (1) | JPH04502904A (es) |
KR (1) | KR900701300A (es) |
CN (1) | CN1043263A (es) |
AT (1) | ATE107170T1 (es) |
AU (1) | AU641129B2 (es) |
CA (1) | CA2001150A1 (es) |
DE (1) | DE68916261T2 (es) |
DK (1) | DK71591A (es) |
ES (1) | ES2024729A6 (es) |
HU (1) | HUT57992A (es) |
IL (1) | IL92061A (es) |
WO (1) | WO1990004408A1 (es) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU648140B2 (en) * | 1991-02-01 | 1994-04-14 | Virtual Drug Development, Inc. | Reverse antimicrobial peptides and antimicrobial compositions |
US5225399A (en) * | 1991-04-15 | 1993-07-06 | The Children's Hospital Of Philadelphia | Antimicrobial amphiphilic peptides |
US5239059A (en) * | 1991-05-10 | 1993-08-24 | The Children's Hospital Of Philadelphia | Ion-channel forming peptides |
JPH07502979A (ja) * | 1991-07-25 | 1995-03-30 | マゲイニン ファーマス−ティカルズ,インコーポレーテッド | 生物活性ペプチドを利用する口腔内の有害な状態の予防と治療 |
US5593866A (en) * | 1992-08-21 | 1997-01-14 | The University Of British Columbia | Cationic peptides and method for production |
US5847047A (en) * | 1993-06-22 | 1998-12-08 | E. I. Du Pont De Nemours And Company | Antimicrobial composition of a polymer and a peptide forming amphiphilic helices of the magainin-type |
US6057291A (en) | 1995-06-02 | 2000-05-02 | University Of British Columbia | Antimicrobial cationic peptides |
ES2316154T3 (es) | 1995-08-23 | 2009-04-01 | University Of British Columbia | Peptidos cationicos antimicrobianos y procedimientos de seleccion de los mismos. |
FR2767323B1 (fr) * | 1997-08-12 | 2001-01-05 | Synt Em | Peptides lineaires derives de peptides antibiotiques, leur preparation et leur utilisation pour vectoriser des substances actives |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4507230A (en) * | 1982-05-12 | 1985-03-26 | Research Corporation | Peptide synthesis reagents and method of use |
WO1988006597A1 (en) * | 1987-03-04 | 1988-09-07 | The United States Of America, As Represented By Th | New synthetic bioactive compounds and method of producing bioactive effect |
-
1989
- 1989-10-18 DE DE68916261T patent/DE68916261T2/de not_active Expired - Fee Related
- 1989-10-18 AT AT89912164T patent/ATE107170T1/de not_active IP Right Cessation
- 1989-10-18 WO PCT/US1989/004664 patent/WO1990004408A1/en active IP Right Grant
- 1989-10-18 EP EP89912164A patent/EP0441832B1/en not_active Expired - Lifetime
- 1989-10-18 HU HU896376A patent/HUT57992A/hu unknown
- 1989-10-18 AU AU45028/89A patent/AU641129B2/en not_active Ceased
- 1989-10-18 JP JP1511302A patent/JPH04502904A/ja active Pending
- 1989-10-20 CA CA002001150A patent/CA2001150A1/en not_active Abandoned
- 1989-10-20 IL IL9206189A patent/IL92061A/en not_active IP Right Cessation
- 1989-10-20 ES ES8903535A patent/ES2024729A6/es not_active Expired - Fee Related
- 1989-10-21 CN CN89108485A patent/CN1043263A/zh active Pending
-
1990
- 1990-06-21 KR KR1019900701330A patent/KR900701300A/ko not_active Application Discontinuation
-
1991
- 1991-04-19 DK DK071591A patent/DK71591A/da unknown
Also Published As
Publication number | Publication date |
---|---|
AU641129B2 (en) | 1993-09-16 |
DE68916261D1 (de) | 1994-07-21 |
HU896376D0 (en) | 1991-07-29 |
EP0441832B1 (en) | 1994-06-15 |
AU4502889A (en) | 1990-05-14 |
JPH04502904A (ja) | 1992-05-28 |
CN1043263A (zh) | 1990-06-27 |
EP0441832A1 (en) | 1991-08-21 |
CA2001150A1 (en) | 1990-04-21 |
HUT57992A (en) | 1992-01-28 |
ATE107170T1 (de) | 1994-07-15 |
DK71591D0 (da) | 1991-04-19 |
IL92061A0 (en) | 1990-07-12 |
KR900701300A (ko) | 1990-12-01 |
DK71591A (da) | 1991-06-21 |
WO1990004408A1 (en) | 1990-05-03 |
DE68916261T2 (de) | 1994-09-22 |
IL92061A (en) | 1994-01-25 |
EP0441832A4 (en) | 1992-10-28 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD1A | Patent lapsed |
Effective date: 20010201 |