ES2019721A6 - Method of formation of a molecula of a monoclonal antibody that immunorreacciona with a site of unión induced by receiver. (Machine-translation by Google Translate, not legally binding) - Google Patents

Method of formation of a molecula of a monoclonal antibody that immunorreacciona with a site of unión induced by receiver. (Machine-translation by Google Translate, not legally binding)

Info

Publication number
ES2019721A6
ES2019721A6 ES8903328A ES8903328A ES2019721A6 ES 2019721 A6 ES2019721 A6 ES 2019721A6 ES 8903328 A ES8903328 A ES 8903328A ES 8903328 A ES8903328 A ES 8903328A ES 2019721 A6 ES2019721 A6 ES 2019721A6
Authority
ES
Spain
Prior art keywords
receiver
ligand
unión
translation
induced
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
ES8903328A
Other languages
Spanish (es)
Inventor
Edward F Plow
Mark H Ginsberg
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Scripps Research Institute
Original Assignee
Scripps Clinic and Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scripps Clinic and Research Foundation filed Critical Scripps Clinic and Research Foundation
Publication of ES2019721A6 publication Critical patent/ES2019721A6/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/566—Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagents where possible specific carrier or receptor proteins are classified with their target compounds
    • G01N33/567—Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagents where possible specific carrier or receptor proteins are classified with their target compounds utilising isolate of tissue or organ as binding agent
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C07K14/75—Fibrinogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/36—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against blood coagulation factors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56966—Animal cells
    • G01N33/56972—White blood cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

A method of forming a molecule of a monoclonal which immunoreacts unión with a receiver site induced. It described a method of forming monoclonal antibody comprising: a) immunizing a mammal with a composition; b) removing antibody-producing cells from said animal; c) treating said cells with a transforming agent; d) cloning cells treated in step c); e) assaying the culture medium knitting cloned transformados; f) growing said transforming cloned; g) removing said secreted antibody molecules from the culture medium of step f). Which antibodies immunoreact with a binding site induced by a receiver (ribs), expressed in terms of a ligand when said ligand is present in a receptor-ligand, but not immunoreact with said ligand or the receiver when ligand or receiver are cited free in solution. (Machine-translation by Google Translate, not legally binding)
ES8903328A 1988-10-03 1989-10-03 Method of formation of a molecula of a monoclonal antibody that immunorreacciona with a site of unión induced by receiver. (Machine-translation by Google Translate, not legally binding) Expired - Fee Related ES2019721A6 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US25275388A 1988-10-03 1988-10-03
US41502989A 1989-09-29 1989-09-29

Publications (1)

Publication Number Publication Date
ES2019721A6 true ES2019721A6 (en) 1991-07-01

Family

ID=26942630

Family Applications (1)

Application Number Title Priority Date Filing Date
ES8903328A Expired - Fee Related ES2019721A6 (en) 1988-10-03 1989-10-03 Method of formation of a molecula of a monoclonal antibody that immunorreacciona with a site of unión induced by receiver. (Machine-translation by Google Translate, not legally binding)

Country Status (8)

Country Link
JP (1) JP2937474B2 (en)
AU (1) AU639671B2 (en)
CA (1) CA2000044A1 (en)
DK (1) DK173362B1 (en)
ES (1) ES2019721A6 (en)
FI (1) FI101808B1 (en)
NO (1) NO301237B1 (en)
PT (1) PT91889B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201014715D0 (en) * 2010-09-06 2010-10-20 Vib Vzw Nanobodies stabilizing functional conformational states of GPCRS

Also Published As

Publication number Publication date
JPH04501665A (en) 1992-03-26
FI101808B (en) 1998-08-31
CA2000044A1 (en) 1990-04-03
FI911586A0 (en) 1991-04-02
DK173362B1 (en) 2000-08-14
FI101808B1 (en) 1998-08-31
NO911300D0 (en) 1991-04-03
PT91889B (en) 1995-07-03
AU639671B2 (en) 1993-08-05
PT91889A (en) 1990-04-30
NO911300L (en) 1991-04-19
NO301237B1 (en) 1997-09-29
AU4652489A (en) 1990-05-14
JP2937474B2 (en) 1999-08-23
DK57891D0 (en) 1991-04-02
DK57891A (en) 1991-05-31

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Legal Events

Date Code Title Description
SA6 Expiration date (snapshot 920101)

Free format text: 2009-10-03

FD1A Patent lapsed

Effective date: 20061004