ES2013799A6 - Cyclohexyl phenyl ketone derivatives, process for their preparation and their use as intermediates - Google Patents

Cyclohexyl phenyl ketone derivatives, process for their preparation and their use as intermediates

Info

Publication number
ES2013799A6
ES2013799A6 ES888802821A ES8802821A ES2013799A6 ES 2013799 A6 ES2013799 A6 ES 2013799A6 ES 888802821 A ES888802821 A ES 888802821A ES 8802821 A ES8802821 A ES 8802821A ES 2013799 A6 ES2013799 A6 ES 2013799A6
Authority
ES
Spain
Prior art keywords
intermediates
phenyl ketone
cyclohexyl phenyl
preparation
ketone derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
ES888802821A
Other languages
Spanish (es)
Inventor
Alain Heymes
Michel Bouisset
Andre Bousquet
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi SA
Original Assignee
Sanofi SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi SA filed Critical Sanofi SA
Publication of ES2013799A6 publication Critical patent/ES2013799A6/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

There are described novel cyclohexyl phenyl ketone derivatives of the formula (I) < IMAGE > in which R is alkyl having 1 to 4 carbon atoms and R1 is hydrogen or halogen. The derivatives according to the invention are suitable as intermediates and in particular for the final synthesis of 1,4-benzodiazepine derivatives, such as tetrazepam, which act on the central nervous system.
ES888802821A 1987-09-16 1988-09-15 Cyclohexyl phenyl ketone derivatives, process for their preparation and their use as intermediates Expired - Fee Related ES2013799A6 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8712842A FR2620444B1 (en) 1987-09-16 1987-09-16 CYCLOHEXYL PHENYL CETONE DERIVATIVES, THEIR PREPARATION PROCESS AND THEIR USE AS SYNTHESIS INTERMEDIATES

Publications (1)

Publication Number Publication Date
ES2013799A6 true ES2013799A6 (en) 1990-06-01

Family

ID=9354955

Family Applications (1)

Application Number Title Priority Date Filing Date
ES888802821A Expired - Fee Related ES2013799A6 (en) 1987-09-16 1988-09-15 Cyclohexyl phenyl ketone derivatives, process for their preparation and their use as intermediates

Country Status (4)

Country Link
DE (1) DE3831543A1 (en)
ES (1) ES2013799A6 (en)
FR (1) FR2620444B1 (en)
IT (1) IT1223826B (en)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3714145A (en) * 1961-02-06 1973-01-30 American Home Prod 1,4-benzodiazepine-2-ones and intermediates
US3950526A (en) * 1970-04-20 1976-04-13 Sumitomo Chemical Company, Limited Quinazoline derivatives in pharmaceutical compositions for treating pain and inflammation

Also Published As

Publication number Publication date
IT1223826B (en) 1990-09-29
IT8867821A0 (en) 1988-09-15
FR2620444B1 (en) 1990-04-13
DE3831543A1 (en) 1989-03-30
FR2620444A1 (en) 1989-03-17

Similar Documents

Publication Publication Date Title
IL102208A0 (en) Azanorbornane derivatives
ES8406477A1 (en) Beta-carbolines, process for their preparation and pharmaceutical compositions containing them.
HUT70499A (en) Fluoroalkoxybenzaldehyde derivatives and process for producing them
FI932229A (en) AZABICYCLISKA BRYGGDERIVAT
IL108769A0 (en) Spirocyclic piperidine derivatives
MX9205242A (en) HETERO-CYCLE COMPOUNDS CONTAINING MELTED TRICYCLIC NITROGEN.
IL114794A0 (en) Peptidic compounds analogous to distramycin process for their preparation and their use
ATE28874T1 (en) 3,6-DISUBSTITUTED TRIAZOLO(3,4A&gt;PHTHALAZINE DERIVATIVES.
MY102117A (en) Naphthquinone derivatives
TW427982B (en) Polysubstituted 3-acylamino-5-phenyl-1,4-benzodiazepin-2-one derivatives, process for their preparation and the pharmaceutical compositions containing them
GR3030733T3 (en) Sulphamate derivatives of 1,3,5(10)-estratriene derivatives, methods of producing them and pharmaceutical compounds containing them
ES8505518A1 (en) Amino-acids derivatives, process for their preparation and their use.
ATE83235T1 (en) QUINOLINECARBONIC BORIC ACID ANHYDRIDES AND METHOD OF PREPARATION.
ATE49957T1 (en) ADAMANTANAMINE DERIVATIVES, METHOD OF PREPARATION AND MEDICATIONS CONTAINING THEM.
ES2013799A6 (en) Cyclohexyl phenyl ketone derivatives, process for their preparation and their use as intermediates
AU2088388A (en) Process for manufacturing 2,5-diamino-6-nitro-pyridine derivatives, their use in hair dyes, and new 2,5-diamino-6-nitro-pyridine derivatives
EG15649A (en) Procede de preparations nouveaux derives de la piperazinyl-2-phenyl-4-quinazoline
ES8604843A1 (en) Acetylene derivatives for the treatment of hypertension and angina.
GR80173B (en) Spiro (benzofuran-azalkanes), method for their preparation and their use as medicaments
ES466245A1 (en) 1,2,3,4,4a,10b-hexahydro-benz(f)isouqinolines
ES8601917A1 (en) Substituted 4.5-dihydro-6-vinyl-3(2H)-pyridazinones and 6-vinyl-3(2H)-pyridazinones and process for producing the same.
GB2018755A (en) Benzylidene esters

Legal Events

Date Code Title Description
SA6 Expiration date (snapshot 920101)

Free format text: 2008-09-15

FD1A Patent lapsed

Effective date: 20001009