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Pfizer Italia SRL
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Farmaceutici Italia SpA
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Application filed by Farmaceutici Italia SpAfiledCriticalFarmaceutici Italia SpA
Priority to ES0201177ApriorityCriticalpatent/ES201177A1/es
Publication of ES201177A1publicationCriticalpatent/ES201177A1/es
Organic Low-Molecular-Weight Compounds And Preparation Thereof
(AREA)
Abstract
Procedimiento para preparación de los treo-l-p.nitrofenil-2-acilamino-1 3-propandioles caracterizado porque se transforma primero tre o-1-fenil-1 3-diaciloxi-2-aminopropanos clorhidratos correspondientes por tratamiento a temperaturas comprendidas entre 0º y 30º C. con ácido clorhídrico gaseoso disueltro en un disolvente anhiro y porque los clorhidratos 0 0-diacílicos así obtenidos son nitrados a temperaturas inferiores a 0º C y seguidamente sometidos a la migración a la posición N de uno de los grupos acílicos y a la saponificación simultánea del grupo acílico que ha quedado en la posición 0.
ES0201177A1951-12-281951-12-28UN PROCEDIMIENTO PARA LA PREPARACIoN DE LOS TREO-1-P. NITROFENIL-2-ACETILAMINO-1,3-PROPANDIOLES
ExpiredES201177A1
(es)