ES2010445A6 - Perfluorochemical emulsion with stabilized vesicles. - Google Patents
Perfluorochemical emulsion with stabilized vesicles.Info
- Publication number
- ES2010445A6 ES2010445A6 ES8900889A ES8900889A ES2010445A6 ES 2010445 A6 ES2010445 A6 ES 2010445A6 ES 8900889 A ES8900889 A ES 8900889A ES 8900889 A ES8900889 A ES 8900889A ES 2010445 A6 ES2010445 A6 ES 2010445A6
- Authority
- ES
- Spain
- Prior art keywords
- perfluorochemical
- stabilized vesicles
- vesicles
- perfluorochemical emulsion
- emulsion
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0026—Blood substitute; Oxygen transporting formulations; Plasma extender
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/02—Halogenated hydrocarbons
- A61K31/025—Halogenated hydrocarbons carbocyclic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
- A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
- A61K9/1273—Polymersomes; Liposomes with polymerisable or polymerised bilayer-forming substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/08—Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock
Abstract
A stable perfluorochemical emulsion is provided which comprises perfluorochemical particles in stabilized vesicles. The vesicles comprise a biocompatible polymer formed by coating the perfluorochemical particles with one or more phospholipid monomer(s) and polymerizing the monomer(s).
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US16669088A | 1988-03-11 | 1988-03-11 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2010445A6 true ES2010445A6 (en) | 1989-11-01 |
Family
ID=22604316
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES8900889A Expired ES2010445A6 (en) | 1988-03-11 | 1989-03-10 | Perfluorochemical emulsion with stabilized vesicles. |
Country Status (4)
Country | Link |
---|---|
EP (1) | EP0417104A4 (en) |
JP (1) | JPH02258050A (en) |
ES (1) | ES2010445A6 (en) |
WO (1) | WO1989008459A1 (en) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5219538A (en) * | 1987-03-13 | 1993-06-15 | Micro-Pak, Inc. | Gas and oxygen carrying lipid vesicles |
US5196199A (en) * | 1990-12-14 | 1993-03-23 | Fuisz Technologies Ltd. | Hydrophilic form of perfluoro compounds and method of manufacture |
DE4221256C2 (en) * | 1992-06-26 | 1997-07-10 | Lancaster Group Ag | Galenic composition for topical use |
US5641509A (en) * | 1992-06-26 | 1997-06-24 | Lancaster Group Ag | Preparation for topical use |
DE4221255C2 (en) * | 1992-06-26 | 1994-09-15 | Lancaster Group Ag | Cosmetolipid-containing cosmetic |
DE4221268C2 (en) * | 1992-06-26 | 1997-06-12 | Lancaster Group Ag | Use of a dermatological to support the oxygen transport in the skin |
DE4221269C1 (en) * | 1992-06-26 | 1993-12-09 | Lancaster Group Ag | Preparation for topical use |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5331209B2 (en) * | 1973-10-05 | 1978-09-01 | ||
JPS55100312A (en) * | 1979-01-25 | 1980-07-31 | Toshiro Wada | Contrast medium for blood vessel |
US4252827A (en) * | 1979-05-23 | 1981-02-24 | The Green Cross Corporation | Oxygen-transferable fluorocarbon emulsion |
US4569784A (en) * | 1980-11-17 | 1986-02-11 | Adamantech, Inc. | Preparation of a gel having gas transporting capability |
US4443480A (en) * | 1982-04-12 | 1984-04-17 | Children's Hospital Medical Center | Artificial blood and other gas transport agents |
US4423077A (en) * | 1982-07-27 | 1983-12-27 | The University Of Pennsylvania | Perfluorochemical emulsion artificial blood |
US4497829A (en) * | 1982-07-27 | 1985-02-05 | The University Of Pennsylvania | Process for preparing perfluorochemical emulsion artificial blood |
GB8407557D0 (en) * | 1984-03-23 | 1984-05-02 | Hayward J A | Polymeric lipsomes |
US4963367A (en) * | 1984-04-27 | 1990-10-16 | Medaphore, Inc. | Drug delivery compositions and methods |
US4814446A (en) * | 1985-09-17 | 1989-03-21 | Biomed-Technology, Inc. | Fluorinated triethylenediamine as an oxygen transport agent |
-
1989
- 1989-03-10 JP JP1059471A patent/JPH02258050A/en active Pending
- 1989-03-10 ES ES8900889A patent/ES2010445A6/en not_active Expired
- 1989-03-10 WO PCT/US1989/000985 patent/WO1989008459A1/en not_active Application Discontinuation
- 1989-03-10 EP EP19890903649 patent/EP0417104A4/en not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
EP0417104A1 (en) | 1991-03-20 |
JPH02258050A (en) | 1990-10-18 |
EP0417104A4 (en) | 1991-10-30 |
WO1989008459A1 (en) | 1989-09-21 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD1A | Patent lapsed |
Effective date: 19980401 |