ES2009858A6 - Un procedimiento para la preparacion de un anticuerpo monoclonal humano capaz de reconocer multiples serotipos de pseudomonas aeruginosa. - Google Patents

Un procedimiento para la preparacion de un anticuerpo monoclonal humano capaz de reconocer multiples serotipos de pseudomonas aeruginosa.

Info

Publication number
ES2009858A6
ES2009858A6 ES8603348A ES8603348A ES2009858A6 ES 2009858 A6 ES2009858 A6 ES 2009858A6 ES 8603348 A ES8603348 A ES 8603348A ES 8603348 A ES8603348 A ES 8603348A ES 2009858 A6 ES2009858 A6 ES 2009858A6
Authority
ES
Spain
Prior art keywords
antibodies
pseudomonas aeruginosa
translation
monoclonal antibody
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES8603348A
Other languages
English (en)
Inventor
Anthony W Siadak
Mae J Rosok
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Genetic Systems Corp
Original Assignee
Genetic Systems Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genetic Systems Corp filed Critical Genetic Systems Corp
Publication of ES2009858A6 publication Critical patent/ES2009858A6/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1203—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria
    • C07K16/1214—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria from Pseudomonadaceae (F)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

UN PROCEDIMIENTO PARA LA PREPARACION DE UN ANTICUERPO MONOCLONAL HUMANO CAPAZ DE RECONOCER MULTIPLES SEROTIPOS DE PSEDOMONAS AERUGINOSA. ESTOS ANTICUERPOS SON CAPACES DE UNIRSE A LAS MOLECULAS DE LIPOPOLISACARIDOS DE CEPAS SELECCIONADAS DE PSEUDOMONAS AERUGINOSA Y SON PROTECTORES FRENTE A LOS ATAQUES LETALES DE ESTE MICROORGANISMO. LOS ANTICUERPOS DE LA INVENCION SE PUEDEN OBTENER POR TRANSFORMACION DE LINFOCITOS B PROCEDENTES DE UN DONANTE EXPUESTO A PSEUDOMONAS AERUGINOSA CON EL VIRUS DE EPSTEIN-BARR, O POR FUSION DE UNA LINEA CELULAR INMORTAL CON LINFOCITOS B HUMANOS PARA OBTENER UN HIBRIDOMA QUE EXPRESE DICHOS ANTICUERPOS O POR AISLAMIENTO DE LOS GENES QUE CODIFICAN A DICHOS ANTICUERPOS Y, POSTERIORMENTE INSERCION EN UN VECTOR DE EXPRESION Y EN UNA CELULA HUESPED ADECUADA. LOS ANTICUERPOS SON ADECUADOS PARA EL TRATAMIENTO DE INFECCIONES OCASIONADOS POR MICROORGANISMOS GRAN-NEGATIVOS Y ADEMAS PUEDEN USARSE EN UN EQUIPO Y EN UN METODO PARA DETECTAR LA PRESENCIA DE PEUDOMONAS AERUGINOSA ENUNA MUESTRA SANGUINEA.
ES8603348A 1985-12-10 1986-12-10 Un procedimiento para la preparacion de un anticuerpo monoclonal humano capaz de reconocer multiples serotipos de pseudomonas aeruginosa. Expired ES2009858A6 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US80739485A 1985-12-10 1985-12-10

Publications (1)

Publication Number Publication Date
ES2009858A6 true ES2009858A6 (es) 1989-10-16

Family

ID=25196273

Family Applications (1)

Application Number Title Priority Date Filing Date
ES8603348A Expired ES2009858A6 (es) 1985-12-10 1986-12-10 Un procedimiento para la preparacion de un anticuerpo monoclonal humano capaz de reconocer multiples serotipos de pseudomonas aeruginosa.

Country Status (5)

Country Link
AU (2) AU6639186A (es)
ES (1) ES2009858A6 (es)
GR (1) GR862884B (es)
OA (1) OA08559A (es)
ZA (1) ZA868673B (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU615162B2 (en) * 1986-07-03 1991-09-26 Genetic Systems Corporation Monoclonal antibodies to pseudomonas aeruginosa flagella
WO1988004669A1 (en) * 1986-12-15 1988-06-30 Mitsui Toatsu Chemicals, Inc. Human monoclonal antibody and drug for prophylaxis and treatment of infectious diseases comprising same as effective ingredient
EP0382031A3 (en) * 1989-02-10 1991-06-26 Miles Inc. Monoclonal antibodies in immune serum globulin

Also Published As

Publication number Publication date
ZA868673B (en) 1988-07-27
AU6639186A (en) 1987-06-11
AU6596390A (en) 1991-03-21
OA08559A (fr) 1988-09-30
GR862884B (en) 1987-04-14

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Legal Events

Date Code Title Description
SA6 Expiration date (snapshot 920101)

Free format text: 2006-12-10