ES2008631A6 - Thiophene carboxamide - Google Patents

Thiophene carboxamide

Info

Publication number
ES2008631A6
ES2008631A6 ES8803045A ES8803045A ES2008631A6 ES 2008631 A6 ES2008631 A6 ES 2008631A6 ES 8803045 A ES8803045 A ES 8803045A ES 8803045 A ES8803045 A ES 8803045A ES 2008631 A6 ES2008631 A6 ES 2008631A6
Authority
ES
Spain
Prior art keywords
alkyl
phenyl
substd
alkenyloxy
opt
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES8803045A
Other languages
Spanish (es)
Inventor
Fernandez M Isabel Fernandez
Terrance M Hotten
David Edward Tupper
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Lilly SA
Lilly Industries Ltd
Original Assignee
Lilly SA
Lilly Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly SA, Lilly Industries Ltd filed Critical Lilly SA
Priority to ES8803045A priority Critical patent/ES2008631A6/en
Publication of ES2008631A6 publication Critical patent/ES2008631A6/en
Expired legal-status Critical Current

Links

Abstract

The derivs. are of formula (I), in which R1, R2 and R3 are H, OH, halogen, NO2, NH2, 2-5C acylamino, 1-4C alkyl, CHO, CH2OH, CH2O-1-4C alkyl, COOH, CO-1-3C alkyl, 1-4C alkoxy, 2-4C alkenyloxy, 1-4C alkylthio, alkylsulphinyl or alkyl sulphonyl, N-substd. heterocycle, opt. substd. phenyl, phenylthio, phenyl sulphinyl, phenyl sulphonyl or phenyl-sulphonamido, or R1 and R2 together form a 3-5C alkylene bridge, one of R2 and R3 being 1-4C alkoxy or 2-4C alkenyloxy, and X is (CH2)nNR4R4, in which R4 is 1-4C alkyl, 2-4C alkenyl or opt. substd. benzyl, and n is 1, 2 or 3. They act on the central nervous system in treatment of vomiting, depression, anxiety and certain psychotic states, and are made by reacting a cpd. (II) in which Z is halogen, OH or OR and R is an active gp. with an amine X-NH2.
ES8803045A 1988-10-06 1988-10-06 Thiophene carboxamide Expired ES2008631A6 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
ES8803045A ES2008631A6 (en) 1988-10-06 1988-10-06 Thiophene carboxamide

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES8803045A ES2008631A6 (en) 1988-10-06 1988-10-06 Thiophene carboxamide

Publications (1)

Publication Number Publication Date
ES2008631A6 true ES2008631A6 (en) 1989-07-16

Family

ID=8258374

Family Applications (1)

Application Number Title Priority Date Filing Date
ES8803045A Expired ES2008631A6 (en) 1988-10-06 1988-10-06 Thiophene carboxamide

Country Status (1)

Country Link
ES (1) ES2008631A6 (en)

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Legal Events

Date Code Title Description
SA6 Expiration date (snapshot 920101)

Free format text: 2008-10-06

FD1A Patent lapsed

Effective date: 20000201