ES2001392A6 - Un procedimiento para la preparacion de polipeptidos analogos a superoxidos dismutasa humana. - Google Patents

Un procedimiento para la preparacion de polipeptidos analogos a superoxidos dismutasa humana.

Info

Publication number
ES2001392A6
ES2001392A6 ES8601311A ES8601311A ES2001392A6 ES 2001392 A6 ES2001392 A6 ES 2001392A6 ES 8601311 A ES8601311 A ES 8601311A ES 8601311 A ES8601311 A ES 8601311A ES 2001392 A6 ES2001392 A6 ES 2001392A6
Authority
ES
Spain
Prior art keywords
gly
val
lys
asp
ala
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES8601311A
Other languages
English (en)
Inventor
Hitoshi Sagai
Masayasu Takahara
Shigeo Katsuragi
Junboku Kajiwara
Harumi Masujima
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Asahi Kasei Corp
Original Assignee
Toyo Jozo KK
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Toyo Jozo KK filed Critical Toyo Jozo KK
Publication of ES2001392A6 publication Critical patent/ES2001392A6/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0089—Oxidoreductases (1.) acting on superoxide as acceptor (1.15)

Abstract

UN PROCEDIMIENTO PARA LA PREPARACION DE POLIPEPTIDOS ANALOGOS A SUPEROXIDO DISMUTASA HUMANA. LOS POLIP''EWPTIDOS DE FORMULA (I) (DONDE X1 REPRESENTA UN ATOMO DE HIDROGENO, UN GRUPO ACETILO O UN RESTO DE UN AMINOACIDO, X2 REPRESENTA UN RESTO DE AMINOACIDO Y X3 REPRESENTA UN RESTO DE UN AMINOACIDO DISTINTO DE CYS) SE OBTIENEN CULTIVANDO CELULAS, CADA UNA DE LAS CUALES CONTIENE UN ADN RECOMBINANTE DE UN ACIDO POLIDESOXIRRIBONUCLEICO QUE TIENE UNA SECUENCIA DE BASES POR LA QUE EL POLIPEPTIDO ESTA CODIFICADO Y UN VECTOR REPLICATIVO, EN UN MEDIO DE CULTIVO QUE REPLICA EL POLIPEPTIDO Y DESPUES RECOGER EL POLIPEPTIDO ASI PRODUCIDO.
ES8601311A 1985-08-23 1986-08-22 Un procedimiento para la preparacion de polipeptidos analogos a superoxidos dismutasa humana. Expired ES2001392A6 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP18524685 1985-08-23

Publications (1)

Publication Number Publication Date
ES2001392A6 true ES2001392A6 (es) 1988-05-16

Family

ID=16167445

Family Applications (1)

Application Number Title Priority Date Filing Date
ES8601311A Expired ES2001392A6 (es) 1985-08-23 1986-08-22 Un procedimiento para la preparacion de polipeptidos analogos a superoxidos dismutasa humana.

Country Status (6)

Country Link
US (1) US4818698A (es)
JP (1) JPH0755146B2 (es)
DE (1) DE3628508A1 (es)
ES (1) ES2001392A6 (es)
IT (1) IT1196591B (es)
SE (1) SE469692B (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5196335A (en) * 1983-04-29 1993-03-23 Yeda Research And Development Co., Ltd. Human superoxide dismutase cDNA
US5714362A (en) * 1983-04-29 1998-02-03 Yeda Research And Development Co. Ltd. Human superoxide dismutase cDNA
US5162217A (en) * 1984-08-27 1992-11-10 Bio-Technology General Corp. Plasmids for expression of human superoxide dismutase (SOD) analogs containing lambda PL promoter with engineered restriction site for substituting ribosomal binding sites and methods of use thereof
US6030611A (en) * 1984-08-27 2000-02-29 Bio-Technology General Corp. Therapeutic SOD compositions and uses thereof
EP0213628A3 (en) * 1985-09-03 1988-09-21 Yeda Research And Development Company, Ltd. Expression of superoxide dismutase in eukaryotic cells
CA1289092C (en) * 1987-01-15 1991-09-17 Robert A. Hallewell Thermostable human cu/zn superoxide dismutase muteins
EP0557417A4 (en) * 1990-11-14 1994-06-08 Uab Research Foundation Compositions for reducing oxidative injury
EP2440568B1 (en) * 2009-06-02 2015-02-25 Brandeis University Cross-linking of superoxide dismutase monomers
CN114480445B (zh) * 2022-01-26 2023-06-27 西南交通大学 一种人源超氧化物歧化酶hSOD1突变体的制备及其应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL90047A (en) * 1982-10-19 1992-12-01 Cetus Oncology Corp Cysteine-depleted biologically active muteins other than interferon - '
US4588585A (en) * 1982-10-19 1986-05-13 Cetus Corporation Human recombinant cysteine depleted interferon-β muteins
US4518584A (en) * 1983-04-15 1985-05-21 Cetus Corporation Human recombinant interleukin-2 muteins

Also Published As

Publication number Publication date
SE8603546L (sv) 1987-02-24
DE3628508A1 (de) 1987-03-12
SE8603546D0 (sv) 1986-08-22
US4818698A (en) 1989-04-04
JPS62130684A (ja) 1987-06-12
JPH0755146B2 (ja) 1995-06-14
SE469692B (sv) 1993-08-23
IT1196591B (it) 1988-11-16
IT8648395A0 (it) 1986-08-21

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Owner name: ASAHI KASEI KABUSHIKI KAISHA