ES158411A1 - PROCEDURE FOR OBTAINING SULPHANILAMIDOPYRIMIDINES - Google Patents

PROCEDURE FOR OBTAINING SULPHANILAMIDOPYRIMIDINES

Info

Publication number
ES158411A1
ES158411A1 ES0158411A ES158411A ES158411A1 ES 158411 A1 ES158411 A1 ES 158411A1 ES 0158411 A ES0158411 A ES 0158411A ES 158411 A ES158411 A ES 158411A ES 158411 A1 ES158411 A1 ES 158411A1
Authority
ES
Spain
Prior art keywords
amino group
group
procedure
obtaining
amino
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES0158411A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nordmark Werke GmbH
Original Assignee
Nordmark Werke GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nordmark Werke GmbH filed Critical Nordmark Werke GmbH
Publication of ES158411A1 publication Critical patent/ES158411A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/69—Benzenesulfonamido-pyrimidines

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Procedimiento para la obtención de sulfanilamidopirimidinas caracterizado porque derivados del ácido benzolsulfónico que en el grupo sulfo permiten introducir el grupo amino y en posición p respecto al grupo llevan un sustituyente transformable en el grupo amino se hacen reaccionar con 4-aminopiridinas que poseen por lo menos un átomo de hidrógeno ene l grupo amino y además contienen por lo menos un grupo alquilo aralquilo arilo aminialquilo o amino unido al anillo de la pirimidina pudiéndose en los dos últimos casos proteger por acilación los grupos amino con excepción del grupo amino situado en posición 4 en el anillo de la piridina y luego el grupo amino se produce en posición p respecto al grupo sulfonamido.Procedure for obtaining sulfanilamidopyrimidines characterized in that derivatives of benzolsulfonic acid that in the sulfo group allow to introduce the amino group and in position p with respect to the group carry a transformable substituent in the amino group are reacted with 4-aminopyridines that have at least one hydrogen atom in the amino group and also contain at least one alkyl aralkyl aryl aminyalkyl or amino group attached to the pyrimidine ring, in the last two cases the amino groups can be protected by acylation with the exception of the amino group located in position 4 in the pyridine ring and then the amino group occurs in position p relative to the sulfonamido group.

ES0158411A 1941-11-22 1942-08-27 PROCEDURE FOR OBTAINING SULPHANILAMIDOPYRIMIDINES Expired ES158411A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DEN601D DE967884C (en) 1941-11-22 1941-11-22 Process for the preparation of 4- (p-aminobenzenesulfoyl) -amino-2, 6-dimethyl-pyrimidine and 4- (p-aminobenzenesulfoyl) -amino-2,6-diaethyl-5-methylpyrimidine

Publications (1)

Publication Number Publication Date
ES158411A1 true ES158411A1 (en) 1943-03-01

Family

ID=6090543

Family Applications (1)

Application Number Title Priority Date Filing Date
ES0158411A Expired ES158411A1 (en) 1941-11-22 1942-08-27 PROCEDURE FOR OBTAINING SULPHANILAMIDOPYRIMIDINES

Country Status (4)

Country Link
CH (1) CH297013A (en)
DE (1) DE967884C (en)
ES (1) ES158411A1 (en)
FR (2) FR886009A (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE881345C (en) * 1949-06-15 1953-06-29 Nordmark Werke Gmbh Process for the preparation of bis (benzenesulfonyl) -4- (or 6) -aminopyrimidines from 4- (or 6) -aminopyrimidines
FR990389A (en) * 1949-06-15 1951-10-03 Nordmark Werke Gmbh Process for preparing sulfanilamidopyrimidines
US2751388A (en) * 1950-04-07 1956-06-19 Nopco Chem Co Process for preparing benzhydryl ethers
US2792391A (en) * 1954-06-15 1957-05-14 Ciba Pharm Prod Inc Process for the manufacture of sulfonamides
DE1173100B (en) * 1960-08-09 1964-07-02 Hoffmann La Roche Process for the preparation of new 4-sulfanilamido-dialkoxypyrimidines

Also Published As

Publication number Publication date
DE967884C (en) 1957-12-27
FR886009A (en) 1943-10-01
CH297013A (en) 1954-03-15
FR53825E (en) 1946-09-09

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