ES1153708U - Preparation or loading device for syringes or vials with radioactive fluids (Machine-translation by Google Translate, not legally binding) - Google Patents
Preparation or loading device for syringes or vials with radioactive fluids (Machine-translation by Google Translate, not legally binding) Download PDFInfo
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- ES1153708U ES1153708U ES201600146U ES201600146U ES1153708U ES 1153708 U ES1153708 U ES 1153708U ES 201600146 U ES201600146 U ES 201600146U ES 201600146 U ES201600146 U ES 201600146U ES 1153708 U ES1153708 U ES 1153708U
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Abstract
Description
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DESCRIPCIONDESCRIPTION
Dispositivo de preparation o carga para jeringas o viales con llquidos radioactivos.Preparation or loading device for syringes or vials with radioactive liquids.
Sector de la tecnicaTechnology Sector
La presente invention se refiere a un nuevo dispositivo de preparation o carga para jeringas o viales con llquidos radiactivos que por su naturaleza requieren el uso de protection, para la sustancia en si misma y para el operador, esta especialmente disenado en forma de modulos independientes, dotado de un sistema principal actuador, que no entra en contacto con los llquidos y de un sistema fungible que consta de un conjunto de tubos y llaves de 3 vlas, de uso comun en entornos de tipo laboratorio.The present invention relates to a new preparation or loading device for syringes or vials with radioactive liquids that by their nature require the use of protection, for the substance itself and for the operator, is specially designed in the form of independent modules, equipped with a main actuator system, which does not come into contact with liquids and a fungible system consisting of a set of 3-tube tubes and wrenches, commonly used in laboratory-type environments.
El objeto de presente invention es un nuevo dispositivo especialmente disenado para llenar una jeringa o un vial con una combination de fluidos seleccionados mediante la actuation sobre las llaves de 3 vlas, e impulsando el movimiento de los fluidos por la actuation independiente sobre el embolo de la jeringa y el desplazamiento vertical de la jeringa segun la necesidades del operador, brindando la posibilidad del llenado de la jeringa con o sin protector de jeringa. Esto se complementa con un modulo de flujo laminar, motor impulsor con un filtro HEPA o ULPA. capaz de crear un entorno de aire controlado en la zona de conexion de la jeringa o vial, para el caso que la zona donde se instale el dispositivo no cuente con este. De esta forma se pueden preparar jeringas o viales segun se disponga o configure el conjunto de tubos.The object of the present invention is a new device specially designed to fill a syringe or a vial with a combination of fluids selected by actuation on the 3-speed wrenches, and driving the movement of the fluids by the independent actuation on the plunger of the syringe and vertical displacement of the syringe according to the needs of the operator, providing the possibility of filling the syringe with or without syringe protector. This is complemented by a laminar flow module, drive motor with a HEPA or ULPA filter. capable of creating a controlled air environment in the connection area of the syringe or vial, in case the area where the device is installed does not have it. In this way syringes or vials can be prepared as the tube set is arranged or configured.
El dispositivo se sirve de una aplicacion informatica de interfaz amigable, desarrollada particularmente para su control, proporcionando al operador una herramienta de trabajo que favorece no manipular directamente ni los fluidos ni la jeringas o viales una vez preparados con las mezclas de llquidos.The device uses a friendly interface computer application, developed especially for its control, providing the operator with a work tool that favors not directly manipulating the fluids or syringes or vials once prepared with the liquid mixtures.
El dispositivo en conjunto ha sido disenado con la intention de proveer al usuario ventajas especlficas y relevantes respecto a otros dispositivos existentes con prestaciones similares.The device as a whole has been designed with the intention of providing the user with specific and relevant advantages over other existing devices with similar features.
Antecedentes de la inventionBackground of the invention
El mercado actual ofrece escasa variedad en dispositivos para realizar la dispensation de jeringas y menos aun con capacidad para fraccionar en jeringas y en viales. De acuerdo al principio de funcionamientos se pueden referir tres dispositivos: el primero de ellos basa su diseno en bombas del tipo peristalticas, utilizando tubos de dispensacion que se instalan sobre una placa frontal y luego esta sobre las valvulas actuadoras. Este sistema, presenta la desventaja de que el montaje del conjunto de tubos de un solo uso es poco fiable, ya que por el tipo de valvulas usadas, que son muy sensibles a la position de los tubos y montandolos en una placa la probabilidad de fallo aumenta; ademas al no utilizan tarjeta para acoplar las senales de control de las valvulas, estas se recalientan y encasquillan. Este diseno no permite realizar operaciones de medida de la actividad total y presenta alta sensibilidad al error en la medida de actividad dispensada cuando se utiliza protector de jeringa. El segundo dispositivo es un sistema mecanico del tipo balancln, donde la carga de la jeringa es manual. Los dos dispositivos mencionados realizan la misma funcion, teniendo en comun como desventaja la manipulation del vial de origen por parte del usuario. Por ultimo, el tercer dispositivo consta de una bomba y valvulas, controlado mediante un programa de aplicacion, pero tiene la desventaja, debido al diseno de este dispositivo, de que la jeringa situada en el activlmetro permanece fija, no es posible la manipulation por parte del usuario que debe realizar laThe current market offers little variety in devices for dispensing syringes and even less with the capacity to fractionate in syringes and vials. According to the principle of operations, three devices can be referred to: the first of them bases its design on peristaltic pumps, using dispensing tubes that are installed on a faceplate and then on actuator valves. This system has the disadvantage that the assembly of the set of single-use tubes is unreliable, because of the type of valves used, which are very sensitive to the position of the tubes and mounting them on a plate the probability of failure increases; In addition to not using a card to attach the control signals of the valves, these are overheated and boxed. This design does not allow operations to measure total activity and has high sensitivity to error in the measure of activity dispensed when syringe protector is used. The second device is a mechanical system of the balance type, where the loading of the syringe is manual. The two mentioned devices perform the same function, having in common as a disadvantage the manipulation of the original vial by the user. Finally, the third device consists of a pump and valves, controlled by an application program, but has the disadvantage, due to the design of this device, that the syringe located in the activometer remains fixed, manipulation by the part is not possible of the user who must perform the
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lectura de actividad del volumen en esta jeringa, que no es la jeringa final; por lo cual es necesario posteriormente llevar ese volumen a la jeringa final a la que tiene acceso el usuario. Ademas cabe mencionar que al aumentar la cantidad de procedimientos aumenta el tiempo para obtener la jeringa final.volume activity reading in this syringe, which is not the final syringe; Therefore, it is necessary to take that volume to the final syringe to which the user has access. It should also be mentioned that increasing the amount of procedures increases the time to obtain the final syringe.
Explicacion de la invencionExplanation of the invention
El inventor de la presente solicitud ha desarrollado un nuevo dispositivo que comprende un sistema actuador: compuesto a su vez por el modulo de actuation sobre las llaves, escalable de 3 a 5 unidades, servomotores controlables individualmente y con el torque suficiente para accionar las llaves de 3 vlas. Segun la position de las llaves se direcciona el movimiento de los fluidos. El modulo de movimiento lineal: que consta de un eje lineal accionado por un motor de pasos que desplaza en sentido vertical una columna donde se soporta la jeringa entre la posicion superior e inferior. Dentro de la columna soporte se situa un tornillo sin fin accionado por un segundo motor de pasos, que cumple la funcion de actuar sobre el embolo de la jeringa, generando el movimiento de los fluidos.The inventor of the present application has developed a new device comprising an actuator system: in turn composed of the actuation module on the keys, scalable from 3 to 5 units, individually controllable servo motors and with sufficient torque to drive the keys of 3 vlas Depending on the position of the keys, the movement of the fluids is directed. The linear motion module: consisting of a linear axis driven by a stepper motor that vertically displaces a column where the syringe is supported between the upper and lower position. Inside the support column there is an endless screw driven by a second stepper motor, which fulfills the function of acting on the syringe plunger, generating the movement of the fluids.
El inventor de la presente solicitud ha conceptualizado el dispositivo mediante el diseno en una planta muy estrecha y modular de 150 mm de ancho y 150 mm de fondo, que permite disponer de los modules, ya sea, orientado de derecha a izquierda o de izquierda a derecha, lo que posibilita utilizar practicamente cualquier cabina de laboratorio.The inventor of the present application has conceptualized the device by means of the design in a very narrow and modular plant 150 mm wide and 150 mm deep, which allows to have the modules, either oriented from right to left or from left to right, which makes it possible to use virtually any laboratory cabinet.
Las senales de control de los modulos se generan en una tarjeta de microcontrolador de tipo comercial, programada a tal fin. Dicha tarjeta recibe las senales desde una interfaz grafica que se ejecuta en un ordenador tipo PC.The control signals of the modules are generated on a commercial microcontroller card, programmed for this purpose. This card receives the signals from a graphical interface that runs on a PC-type computer.
El sistema fungible se basa en racks o manifolds de 3 o 5 llaves de 3 vlas, y llneas de PVC de tipo estandar. Se han seleccionado componentes de uso estandar en entornos de laboratorio, lo que resulta en un bajo coste del sistema fungible, al evitarse el uso de componentes especlficos o especiales.The fungible system is based on racks or manifolds of 3 or 5 keys of 3 vlas, and PVC lines of standard type. Components of standard use in laboratory environments have been selected, resulting in a low cost of the fungible system, avoiding the use of specific or special components.
Los racks o manifolds de llaves de tres vlas accionadas remotamente mediante el modulo de servomotores independientes que permiten la selection del fluido a cargar, un conjunto de tubos de PVC esteriles, un sistema electromecanico, a traves del cual se realizan movimientos lineales ejecutados mediante dos motores de pasos; uno de estos movimientos desplaza verticalmente sobre un eje, que presenta un soporte fijo solidario para el protector de jeringa, la jeringa introduciendola dentro del sistema de detection y el segundo movimiento permite accionar el embolo de la jeringa, estos movimientos lineales descriptos son independientes el uno del otro. El movimiento lineal del embolo de la jeringa produce el desplazamiento del fluido seleccionado hacia el interior de la jeringa, la circulation de los fluidos se realiza a traves de llaves de tres vlas y tubos de PVC esteriles de un solo uso que, gracias a su configuration, permite la circulacion de los fluidos. sin riesgos de aportar contamination ni al fluido ni al entorno de trabajo (cabina).The racks or manifolds of keys of three vlas operated remotely by means of the module of independent servomotors that allow the selection of the fluid to be loaded, a set of sterile PVC pipes, an electromechanical system, through which linear movements are carried out executed by means of two motors of steps; one of these movements moves vertically on an axis, which has a fixed supportive support for the syringe protector, the syringe introducing it into the detection system and the second movement allows the syringe stroke to be operated, these described linear movements are independent of the one of the other. The linear movement of the plunger of the syringe produces the displacement of the selected fluid into the syringe, the circulation of the fluids is carried out through three-way wrenches and sterile single-use PVC pipes that, thanks to their configuration , allows the circulation of fluids. without risks of contamination to the fluid or the work environment (cabin).
La electronica asociada del dispositivo as! como la parte mecanica se encuentran montadas en un bastidor. Para el correcto funcionamiento del presente dispositivo se han disenado e implementado la pieza de sujecion del ala del embolo solidaria al eje de desplazamiento del embolo, y la pieza que soporta el protector de jeringa que se fija al eje del movimiento de la jeringa.The associated electronics of the device as! as the mechanical part are mounted on a frame. For the correct operation of the present device, the clamping part of the plunger wing integral to the axis of displacement of the plunger has been designed and implemented, and the part that supports the syringe protector that is fixed to the axis of the movement of the syringe.
El dispositivo ha sido disenado de forma que presente una mejora importante respecto de dispositivos comerciales, respecto al hecho de que la jeringa pueda ser llenada posicionada en el extremo superior o en el extremo inferior. En caso de que se encuentre posicionada en el extremo superior, aqul se ubica el protector de jeringas y por tanto seThe device has been designed so that it presents a significant improvement over commercial devices, with respect to the fact that the syringe can be filled positioned at the upper end or at the lower end. If it is positioned at the upper end, the syringe guard is located here and therefore
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permite el llenado de la jeringa con este elemento. En caso de que la jeringa se desplace a la zona inferior, queda introducida en el equipo de detection y por ende el llenado de la jeringa se realizara dentro del equipo de deteccion.It allows the filling of the syringe with this element. In case the syringe is moved to the lower zone, it is inserted in the detection equipment and therefore the filling of the syringe will be carried out within the detection equipment.
Al finalizar el llenado de la jeringa, de acuerdo con lo descrito en el parrafo anterior el operador puede leer la actividad que presente el fluido en la jeringa y manipular la misma con o sin el protector de jeringa blindado.At the end of the filling of the syringe, according to what is described in the previous paragraph, the operator can read the activity that the fluid presents in the syringe and manipulate it with or without the shielded syringe shield.
Ademas el inventor de la presente solicitud ha realizado el diserto de forma modular, esto permite una mejora opcional, que es aumentar el numero de fluidos a combinar, solo hay que agregar tantas llaves de tres vlas y sus respectivos servomotores como fluidos se necesiten utilizar, hasta 5.In addition, the inventor of the present application has made the dissertation in a modular way, this allows an optional improvement, which is to increase the number of fluids to be combined, just add as many keys of three vlas and their respective servomotors as fluids need to be used, up to 5.
Este sistema modular posibilita, dependiendo las caracterlsticas del espacio flsico de la instalacion, elegir la position del modulo de llave de tres vlas y servomotores en el lado izquierdo o derecho del sistema electromecanico de desplazamiento vertical de jeringas.This modular system makes it possible, depending on the characteristics of the physical space of the installation, to choose the position of the key module with three rods and servomotors on the left or right side of the electromechanical system of vertical displacement of syringes.
Una caracterlstica fundamental del diseno es que permite el vaciado de los tubos retornando el fluido al vial de origen quedando la via sin fluido. As! el usuario puede vaciar la jeringa, colocarla en el brazo principal y desplazarla al fondo del detector para leer la actividad residual en la jeringa.A fundamental characteristic of the design is that it allows the emptying of the tubes by returning the fluid to the original vial, leaving the route without fluid. Ace! The user can empty the syringe, place it on the main arm and move it to the bottom of the detector to read the residual activity in the syringe.
Cuando lo que se requiere es el fraccionamiento en viales, se utiliza la jeringa para extraer el llquido del vial principal, es decir como medio de bombeo, extrayendo el contenido del vial principal y fraccionandolo en diferentes viales. Determinandose la actividad contenida en los viales finales por sustraccion de la actividad inicial en la jeringa y las finales sucesivas.When what is required is the fractionation in vials, the syringe is used to extract the liquid from the main vial, that is, as a means of pumping, extracting the contents of the main vial and dividing it into different vials. Determining the activity contained in the final vials by subtracting the initial activity in the syringe and the subsequent ones.
El dispositivo para la manipulation de jeringas se controla mediante una aplicacion informatica desarrollada especlficamente para tal fin, brindando al usuario un entrono amigable de facil utilization. A traves del programa el operador puede seleccionar el fluido, fijar el volumen a desplazar, la direction del fluido, esto es cargar o vaciar la jeringa, subir la jeringa y colocarla en su protector correspondiente o bajar la jeringa para introducirla en el detector, Ademas podra imprimir datos en una etiqueta de identification de la jeringa.The syringe manipulation device is controlled by a computer application specifically developed for this purpose, providing the user with an easy-to-use friendly environment. Through the program the operator can select the fluid, set the volume to be displaced, the direction of the fluid, that is to load or empty the syringe, raise the syringe and place it in its corresponding protector or lower the syringe to introduce it into the detector. You can print data on an identification label on the syringe.
Adicionalmente, el inventor la presente solicitud incorpora una mejora que consiste en un modulo complementario de flujo laminar, el cual consta de un ventilador impulsor y un filtro HEPA o ULPA de 203 x 203 x 69 mm capaz de mantener un flujo de aire laminar a 0.45 m/s, este modulo es para cuando la ubicacion de la instalacion del dispositivo lo requiera.Additionally, the inventor of the present application incorporates an improvement consisting of a complementary module of laminar flow, which consists of a driving fan and a HEPA or ULPA filter of 203 x 203 x 69 mm capable of maintaining a flow of laminar air at 0.45 m / s, this module is for when the location of the device installation requires it.
Breve descripcion de los dibujosBrief description of the drawings
Para complementar la descripcion que se esta realizando y con objeto de ayudar a una mejor comprension de las caracterlsticas de la invention, se acompana como parte integrante de dicha descripcion, dibujos en donde con caracter ilustrativo y no limitativo, se ha representado lo siguiente:To complement the description that is being made and in order to help a better understanding of the characteristics of the invention, it is accompanied as an integral part of said description, drawings in which with an illustrative and non-limiting nature, the following has been represented:
Figura 1.- Muestra una vista frontal del dispositivo de acuerdo con la presente invencion.Figure 1.- Shows a front view of the device according to the present invention.
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Figura 2.- Muestra el diagrama de conexion del sistema fungible disenado de acuerdo con la presente invention, racks 5 llaves de 3 vias, y lmeas de PVC con jeringa y viales.Figure 2.- Shows the connection diagram of the fungible system designed in accordance with the present invention, racks 5 3-way keys, and PVC lines with syringe and vials.
Figuras 3a y 3b.- Muestran una vista frontal del dispositivo de la presente invencion con la jeringa dentro del protector en posicion superior e inferior sin protector dentro del detector, respectivamente.Figures 3a and 3b.- They show a front view of the device of the present invention with the syringe inside the protector in upper and lower position without protector inside the detector, respectively.
Figuras 4a y 4b.- Muestran una vista frontal del dispositivo con la disposition del modulo de llaves y servomotores de la presente invencion, orientados de derecha a izquierda o de izquierda a derecha, respectivamente.Figures 4a and 4b.- They show a front view of the device with the disposition of the module of keys and servo motors of the present invention, oriented from right to left or from left to right, respectively.
Figura 5.- Muestra una vista tridimensional de los accesorios disenados y desarrollados para la construction del dispositivo de la presente invencion.Figure 5.- Shows a three-dimensional view of the accessories designed and developed for the construction of the device of the present invention.
Figura 6.- Muestra la vista frontal el modulo complementario de flujo laminar (1).Figure 6.- The front view shows the complementary laminar flow module (1).
Realization preferente de la invencionPreferred realization of the invention
A continuation, se describe un ejemplo particular de dispositivo de preparation o carga para jeringas o viales con liquides de acuerdo con la presente invencion haciendo referencia a las figuras adjuntas. La figura 1 muestra la vista frontal del dispositivo, donde se aprecian las diferentes partes: (1) modulo de actuation sobre las llaves escalable de 3 a 5 unidades, (2) acople del servomotor a cada llave de 3 vias, (3) motor de pasos que acciona el embolo de la jeringa, (4) modulo de movimiento lineal, que consta de un eje lineal accionado por un motor de pasos que desplaza en sentido vertical la columna donde se soporta la jeringa entre la position superior e inferior, (5) pieza que soporta el protector de jeringa, (6) pieza de sujecion del cuerpo de la jeringa, modulo de movimiento lineal motor de pasos que acciona un tornillo sin fin que se encuentra dentro de la columna soporte, (7) pieza de sujecion del embolo de la jeringa embolo solidaria al tornillo sin fin interior a la columna accionada por motor de pasos (3), (8) sistema de detection para verificar la carga de la jeringa. Para dotar de simplicidad a la figura no se ha dibujado el sistema de fungibles (kit de tubos de PVC, jeringa y viales), que se describe con mas detalle a continuacion.Next, a particular example of a preparation or loading device for syringes or vials with liquids according to the present invention is described with reference to the attached figures. Figure 1 shows the front view of the device, where the different parts are appreciated: (1) module of actuation on the keys scalable from 3 to 5 units, (2) coupling of the servomotor to each key of 3 ways, (3) motor of steps that drives the syringe plunger, (4) linear motion module, consisting of a linear axis driven by a stepper motor that vertically displaces the column where the syringe is supported between the upper and lower position, ( 5) piece that supports the syringe protector, (6) syringe body clamping piece, stepper motor linear motion module that drives an endless screw that is inside the support column, (7) clamping piece from the plunger of the syringe plunger integral to the inner worm screw to the column driven by stepper motor (3), (8) detection system to verify the syringe load. To provide simplicity to the figure, the fungible system (kit of PVC tubes, syringe and vials) has not been drawn, which is described in more detail below.
En la figura 2 se observa el diagrama de conexion del sistema fungible, (1) lmeas de PVC de 30 cm de longitud, con conexion luer macho - macho que conduce los fluidos desde los viales al conjunto de llaves de 3 vias o manifolds, (2) manifolds o racks de 3 6 5 llaves de 3 vias, en esta representation se utiliza un manifold de 5 llaves de 3 vias, (3) filtro de venteo, (4) lmea de PVC de 60 cm de longitud con conexion luer macho - hembra que conduce el fluido seleccionado a la jeringa, (5) jeringa, (6) viales opcionales, como maximo tres y (7) viales principales de liquidos para obtener las alicuotas o diluciones.Figure 2 shows the connection diagram of the fungible system, (1) 30 cm long PVC lines, with male-male luer connection that conducts the fluids from the vials to the 3-way wrench set or manifolds, ( 2) 3 6 5 manifolds or 3-way racks, this representation uses a 5-way 3-way manifold, (3) vent filter, (4) 60 cm long PVC line with male luer connection - female that conducts the selected fluid to the syringe, (5) syringe, (6) optional vials, at most three and (7) main liquid vials to obtain the aliquots or dilutions.
Las figuras 3a y 3b muestran las vistas frontales del dispositivo con el modulo de movimiento lineal con la jeringa dentro del protector en posicion superior y en la posicion inferior dentro del detector, respectivamente. En estas figuras: (1) modulo de movimiento lineal, (2) protector de jeringa y (3) jeringa.Figures 3a and 3b show the front views of the device with the linear motion module with the syringe inside the protector in the upper position and in the lower position inside the detector, respectively. In these figures: (1) linear motion module, (2) syringe protector and (3) syringe.
En las figuras 4a y 4b se observan sendas vistas frontales del dispositivo con la disposicion del modulo de llaves y servomotores de la presente invencion, orientados de derecha a izquierda o de izquierda a derecha, lo que posibilita utilizar practicamente cualquier cabina de laboratorio.Figures 4a and 4b show the front views of the device with the arrangement of the module of keys and servo motors of the present invention, oriented from right to left or from left to right, which makes it possible to use practically any laboratory cabinet.
La figura 5 muestra una vista tridimensional de los componentes disenados y desarrollados para la construccion del dispositivo de la presente invencion. (1) SoporteFigure 5 shows a three-dimensional view of the components designed and developed for the construction of the device of the present invention. (1) Support
principal de desplazamiento lineal, aloja el motor de pasos que acciona el tornillo sinfln que actua sobre el embolo de la jeringa. (2) Soporte fijo para el protector de jeringa. (3) Sujecion del cuerpo de la jeringa. (4) Sujecion del extremo del embolo. (5) Acople del servomotor a la llave de 3 vlas. Estos componentes se fabricaron mediante impresion 3D. 5main linear displacement, houses the stepper motor that drives the screw screw acting on the syringe plunger. (2) Fixed support for the syringe guard. (3) Holding the syringe body. (4) Attachment of the end of the embolus. (5) Attach the servomotor to the 3-speed key. These components were manufactured using 3D printing. 5
En la figura 6 se puede observar (1) el modulo complementary de flujo laminar. Esta opcion permite crear una zona de calidad de aire controlada mediante el flujo laminar de aire filtrado a traves de un filtro HEPA o ULPA, a velocidades de o entorno a 0.45 m/s. Para cabinas que carezcan de esta posibilidad y si los fluidos a fraccionar lo requiriesen.Figure 6 shows (1) the complementary module of laminar flow. This option allows the creation of an air quality zone controlled by the laminar flow of filtered air through a HEPA or ULPA filter, at speeds of or around 0.45 m / s. For cabins that lack this possibility and if the fluids to be fractionated require it.
Claims (9)
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ES201600146U ES1153708Y (en) | 2016-03-03 | 2016-03-03 | Preparation or loading device for syringes or vials with radioactive liquids |
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ES201600146U ES1153708Y (en) | 2016-03-03 | 2016-03-03 | Preparation or loading device for syringes or vials with radioactive liquids |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG1K | Utility model granted |
Effective date: 20160704 |